Results 11 to 20 of about 2,936,789 (384)
Current Pharmaceutical Design, 2021 Background: Retinal imaging for Alzheimer’s disease (AD) pathological features is a potential biomarker for AD. Amyloid β -protein (A β ) containing plaques and abnormally phosphorylated tau (p-tau) pathology have been reported in retinas of AD cases ...
Jorge C. Manzanares +3 more
semanticscholar +3 more sources
Wiener Medizinische Wochenschrift, 2012 Biomarkers are characteristics objectively measured and evaluated as indicators of: normal biologic processes, pathogenic processes, or pharmacologic response(s) to a therapeutic intervention. In environmental research and risk assessment, biomarkers are frequently referred to as indicators of human or environmental hazards.
Harmony, Larson +3 more
+7 more sources
Haptoglobin as a Biomarker [PDF]
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2021 Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a number of regulatory functions. Haptoglobin is an acute phase protein, its concentration in plasma changes in pathology, and the test for its concentration is ...
Naryzny, S. N., Legina, O. K.
openaire +4 more sources
Biomarkers of Cholestasis [PDF]
Biomarkers in Medicine, 2021 Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Pieters, Alanah +5 more
openaire +4 more sources
bioRxiv, 2023 Personalized interventions are deemed vital given the intricate characteristics, advancement, inherent genetic composition, and diversity of cardiovascular diseases (CVDs). The appropriate utilization of artificial intelligence (AI) and machine learning (
William DeGroat +5 more
semanticscholar +1 more source
Small molecule metabolites: discovery of biomarkers and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite signatures that have close proximity to subject’s phenotypic informative dimension,
Shi Qiu +6 more
semanticscholar +1 more source
Scientific Reports, 2023 Over the past decade, automation of digital image analysis has become commonplace in both research and clinical settings. Spurred by recent advances in artificial intelligence and machine learning (AI/ML), tissue sub-compartments and cellular phenotypes ...
Edward D. Bonnevie +7 more
doaj +1 more source
Scientific Reports, 2023 Citrullinated vimentin has been linked to several chronic and autoimmune diseases, but how citrullinated vimentin is associated with disease prevalence and genetic variants in a clinical setting remains unknown.
Cecilie Liv Bager +8 more
doaj +1 more source
Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank
Nature Communications, 2023 The authors report a systematic analyses of blood biomarkers for metabolism against the whole spectrum of diseases in 100,000 individuals and reveals a prominent role of numerous metabolic biomarkers as risk markers beyond heart disease and diabetes ...
H. Julkunen +15 more
semanticscholar +1 more source
Journal of Experimental & Clinical Cancer Research, 2021 Despite the overall clinical success of immune checkpoint inhibitors (ICIs) for treating patients with solid tumors, a large number of patients do not benefit from this approach. Consequently, there is a need for predictive biomarkers. The most prevalent
Christina Jensen +4 more
doaj +1 more source