Results 11 to 20 of about 2,853,474 (383)
Current Opinion in Pulmonary Medicine, 2013 Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core +6 more sources
Current Pharmaceutical Design, 2021 Background: Retinal imaging for Alzheimer’s disease (AD) pathological features is a potential biomarker for AD. Amyloid β -protein (A β ) containing plaques and abnormally phosphorylated tau (p-tau) pathology have been reported in retinas of AD cases ...
Jorge C. Manzanares +3 more
semanticscholar +3 more sources
Haptoglobin as a Biomarker [PDF]
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2021 Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a number of regulatory functions. Haptoglobin is an acute phase protein, its concentration in plasma changes in pathology, and the test for its concentration is ...
O. K. Legina, S. N. Naryzny
openaire +4 more sources
Wiener Medizinische Wochenschrift, 2012 Biomarkers are characteristics objectively measured and evaluated as indicators of: normal biologic processes, pathogenic processes, or pharmacologic response(s) to a therapeutic intervention. In environmental research and risk assessment, biomarkers are frequently referred to as indicators of human or environmental hazards.
Harmony, Larson +3 more
+7 more sources
Biomarkers of Cholestasis [PDF]
Biomarkers in Medicine, 2021 Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Pieters, Alanah +5 more
openaire +4 more sources
Biomedicines, 2023 The focus of this Special Issue on Biomedicines is on the value of “Biomarkers in Pain” from a broad perspective [...]
Anders Larsson +2 more
openaire +5 more sources
Imaging Biomarkers or Biomarker Imaging? [PDF]
Pharmaceuticals, 2014 Since biomarker imaging is traditionally understood as imaging of molecular probes, we highly recommend to avoid any confusion with the previously defined term “imaging biomarkers” and, therefore, only use “molecular probe imaging (MPI)” in that context. Molecular probes (MPs) comprise all kinds of molecules administered to an organism which inherently
Markus Mitterhauser, Wolfgang Wadsak
openaire +4 more sources
Lot-to-Lot Variance in Immunoassays—Causes, Consequences, and Solutions
Diagnostics, 2023 Immunoassays, which have gained popularity in clinical practice and modern biomedical research, play an increasingly important role in quantifying various analytes in biological samples.
Yunyun Luo +5 more
doaj +1 more source
Small molecule metabolites: discovery of biomarkers and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite signatures that have close proximity to subject’s phenotypic informative dimension,
Shi Qiu +6 more
semanticscholar +1 more source
Scientific Reports, 2021 Osteoarthritis (OA) and rheumatoid arthritis (RA) are serious and painful diseases. Protease-activated receptor 2 (PAR2) is involved in the pathology of both OA and RA including roles in synovial hyperplasia, cartilage destruction, osteophyogenesis and ...
Stefania Kalogera +7 more
doaj +1 more source