Results 21 to 30 of about 1,859,513 (388)

Biomarkers in Autism [PDF]

open access: yesFrontiers in Psychiatry, 2014
Autism spectrum disorders (ASDs) are complex, heterogeneous disorders caused by an interaction between genetic vulnerability and environmental factors. In an effort to better target the underlying roots of ASD for diagnosis and treatment, efforts to identify reliable biomarkers in genetics, neuroimaging, gene expression, and measures of the body's ...
Goldani, Andre AS   +4 more
openaire   +5 more sources

MiR-151a: a robust endogenous control for normalizing small extracellular vesicle cargo in human cancer

open access: yesBiomarker Research, 2023
Small extracellular vesicles (sEVs) in the blood of cancer patients contain higher amounts of tumor markers than those identified as free-circulating.
Miranda Burdiel   +17 more
doaj   +1 more source

Molecular Biomarkers in Cancer

open access: yesBiomolecules, 2022
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer, occurrence of cancer, or patient outcome. They may include germline or somatic genetic variants, epigenetic signatures, transcriptional changes, and proteomic ...
V. Sarhadi, G. Armengol
semanticscholar   +1 more source

Biomarkers for Sepsis [PDF]

open access: yesBioMed Research International, 2014
Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful for monitoring the infectious process.
Henriquez-Camacho, Cesar, Losa, Juan
openaire   +4 more sources

NAFLD: Mechanisms, Treatments, and Biomarkers

open access: yesBiomolecules, 2022
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is growing in parallel with the obesity epidemic.
F. Nassir
semanticscholar   +1 more source

Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium

open access: yesNature Reviews Cardiology, 2022
Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and thromboembolic events, owing to excessive inflammation, endothelial cell activation and injury, platelet activation and hypercoagulability.
Diana A Gorog   +16 more
semanticscholar   +1 more source

The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile

open access: yesBMC Endocrine Disorders, 2021
Background Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise in this regard.
Anna Thorsø Larsen   +4 more
doaj   +1 more source

Systematic evaluation of multiple qPCR platforms, NanoString and miRNA-Seq for microRNA biomarker discovery in human biofluids

open access: yesScientific Reports, 2021
Aberrant miRNA expression has been associated with many diseases, and extracellular miRNAs that circulate in the bloodstream are remarkably stable. Recently, there has been growing interest in identifying cell-free circulating miRNAs that can serve as ...
Lewis Z. Hong   +6 more
doaj   +1 more source

Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors

open access: yesBiomarker Research, 2023
Background Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint ...
Dingwei Ye   +16 more
doaj   +1 more source

Integration of Proteomics, Bioinformatics and Systems biology in Brain Injury Biomarker Discovery

open access: yesFrontiers in Neurology, 2013
Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes.
Joy eGuingab-Cagmat   +3 more
doaj   +1 more source

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