Results 21 to 30 of about 2,058,753 (356)
The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting [PDF]
, 2019 The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed ...
Blair, Ian A. +8 more
core +1 more source
Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]
, 2020 Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
core +1 more source
Integration of Proteomics, Bioinformatics and Systems biology in Brain Injury Biomarker Discovery
Frontiers in Neurology, 2013 Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes.
Joy eGuingab-Cagmat +3 more
doaj +1 more source
Biomarker Research, 2023 Background Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint ...
Dingwei Ye +16 more
doaj +1 more source
Biomarkers predictive value for early diagnosis of Stroke- Associated Pneumonia. [PDF]
, 2019 To confirm the diagnostic accuracy of candidate biomarkers in stroke-associ- ated pneumonia (SAP), we prospectively enrolled ischemic stroke patients with NIHSS ≥ 10 on admission from March-2016 to August-2017. Blood samples were collected at baseline,
Mancha Molina, Fernando +6 more
core +1 more source
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 1988 Abstract This article presents a conceptual discussion of some aspects involved in biomarkers in aging. A biomarker of aging is a biological parameter of an organism that either alone or in some multivariate composite will, in the absence of disease, better predict functional capability at some late age than will chronological age.
Baker, George T., Sprott, Richard L.
openaire +8 more sources
The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. [PDF]
, 2014 The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu +4 more
core +2 more sources
Diagnostics, 2023 Sepsis is a highly complex disease caused by a deregulated host’s response to infection [...]
Luisa Agnello, Marcello Ciaccio
openaire +4 more sources
Antioxidants, 2021 Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics.
Pedro Ayuso +2 more
doaj +1 more source
Journal of Stroke, 2013 Major stroke clinical trials have failed during the past decades. The failures suggest the presence of heterogeneity among stroke patients. Biomarkers refer to indicators found in the blood, other body fluids or tissues that predicts physiologic or disease states, increased disease risk, or pharmacologic responses to a therapeutic intervention.
Suk Jae Kim +2 more
openaire +3 more sources