Results 21 to 30 of about 2,936,789 (384)

Biomarkers of aging

open access: yesScience China Life Sciences, 2023
Aging biomarkers are a combination of biological parameters to (i) assess age-related changes, (ii) track the physiological aging process, and (iii) predict the transition into a pathological status. Although a broad spectrum of aging biomarkers has been
H. Bảo   +124 more
semanticscholar   +1 more source

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

open access: yesIntensive Care Medicine, 2023
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or dysregulated host response or response to treatment and/or
P. Póvoa   +14 more
semanticscholar   +1 more source

Intermittent Dynamic Compression Confers Anabolic Effects in Articular Cartilage

open access: yesApplied Sciences, 2021
(1) Background: Mechanical loading is an essential part of the function and maintenance of the joint. Despite the importance of intermittent mechanical loading, this factor is rarely considered in preclinical models of cartilage, limiting their ...
Amalie Engstrøm   +6 more
doaj   +1 more source

Biomarkers in Cancer Detection, Diagnosis, and Prognosis

open access: yesItalian National Conference on Sensors, 2023
Biomarkers are vital in healthcare as they provide valuable insights into disease diagnosis, prognosis, treatment response, and personalized medicine.
Sreyashi Das   +3 more
semanticscholar   +1 more source

Lot-to-Lot Variance in Immunoassays—Causes, Consequences, and Solutions

open access: yesDiagnostics, 2023
Immunoassays, which have gained popularity in clinical practice and modern biomedical research, play an increasingly important role in quantifying various analytes in biological samples.
Yunyun Luo   +5 more
doaj   +1 more source

Biomarkers in long COVID-19: A systematic review

open access: yesFrontiers in Medicine, 2023
Purpose Long COVID, also known as post-acute sequelae of COVID-19, refers to the constellation of long-term symptoms experienced by people suffering persistent symptoms for one or more months after SARS-CoV-2 infection. Blood biomarkers can be altered in
Yun-Ju Lai   +5 more
semanticscholar   +1 more source

The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment

open access: yesScientific Reports, 2021
Osteoarthritis (OA) and rheumatoid arthritis (RA) are serious and painful diseases. Protease-activated receptor 2 (PAR2) is involved in the pathology of both OA and RA including roles in synovial hyperplasia, cartilage destruction, osteophyogenesis and ...
Stefania Kalogera   +7 more
doaj   +1 more source

Biomarkers as Biomedical Bioindicators: Approaches and Techniques for the Detection, Analysis, and Validation of Novel Biomarkers of Diseases

open access: yesPharmaceutics, 2023
A biomarker is any measurable biological moiety that can be assessed and measured as a potential index of either normal or abnormal pathophysiology or pharmacological responses to some treatment regimen.
Anas Ahmad, M. Imran, H. Ahsan
semanticscholar   +1 more source

oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data

open access: yesBriefings Bioinform., 2021
Cell line drug screening datasets can be utilized for a range of different drug discovery applications from drug biomarker discovery to building translational models of drug response.
D. Maeser, Robert F. Gruener, R. Huang
semanticscholar   +1 more source

NTSR1 glycosylation and MMP dependent cleavage generate three distinct forms of the protein

open access: yesScientific Reports, 2023
NTSR1 abnormal expression by cancer cells makes it a strategic target for antitumoral therapies, such as compounds that use NTSR1 binding probes to deliver cytotoxic agents to tumor cells.
Fotine Libanje   +6 more
doaj   +1 more source

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