Results 21 to 30 of about 2,640,873 (286)

Systematic evaluation of multiple qPCR platforms, NanoString and miRNA-Seq for microRNA biomarker discovery in human biofluids

open access: yesScientific Reports, 2021
Aberrant miRNA expression has been associated with many diseases, and extracellular miRNAs that circulate in the bloodstream are remarkably stable. Recently, there has been growing interest in identifying cell-free circulating miRNAs that can serve as ...
Lewis Z. Hong   +6 more
doaj   +1 more source

The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting [PDF]

open access: yes, 2019
The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed ...
Blair, Ian A.   +8 more
core   +1 more source

Biomarkers in emergency medicine [PDF]

open access: yes, 2018
Researchers navigate the ocean of biomarkers searching for proper targets and optimal utilization of them. Emergency medicine builds up the front line to maximize the utility of clinically validated biomarkers and is the cutting edge field to test the ...
Cardelli, P., Hur, M., Somma, S. D.
core   +2 more sources

Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors

open access: yesBiomarker Research, 2023
Background Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint ...
Dingwei Ye   +16 more
doaj   +1 more source

Biomarkers in sepsis. [PDF]

open access: yes, 2013
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core   +1 more source

Integration of Proteomics, Bioinformatics and Systems biology in Brain Injury Biomarker Discovery

open access: yesFrontiers in Neurology, 2013
Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes.
Joy eGuingab-Cagmat   +3 more
doaj   +1 more source

Biomarkers predictive value for early diagnosis of Stroke- Associated Pneumonia. [PDF]

open access: yes, 2019
To confirm the diagnostic accuracy of candidate biomarkers in stroke-associ- ated pneumonia (SAP), we prospectively enrolled ischemic stroke patients with NIHSS ≥ 10 on admission from March-2016 to August-2017. Blood samples were collected at baseline,
Mancha Molina, Fernando   +6 more
core   +1 more source

Biomarkers for the diagnosis and management of heart failure

open access: yesHeart Failure Reviews, 2021
Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating biomarkers reflecting pathophysiological pathways involved in HF development and progression may assist clinicians in early diagnosis and management of HF ...
V. Castiglione   +5 more
semanticscholar   +1 more source

Variability of the Genes Involved in the Cellular Redox Status and Their Implication in Drug Hypersensitivity Reactions

open access: yesAntioxidants, 2021
Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics.
Pedro Ayuso   +2 more
doaj   +1 more source

Precision medicine for suicidality: from universality to subtypes and personalization [PDF]

open access: yes, 2017
Suicide remains a clear, present and increasing public health problem, despite being a potentially preventable tragedy. Its incidence is particularly high in people with overt or un(der)diagnosed psychiatric disorders.
Ballew, A   +19 more
core   +1 more source

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