Results 31 to 40 of about 2,853,474 (383)

Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review

open access: yesCritical Care, 2022
A biomarker describes a measurable indicator of a patient's clinical condition that can be measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis, early disease recognition, risk stratification, appropriate treatment ...
T. Barichello   +3 more
semanticscholar   +1 more source

Molecular Biomarkers in Cancer

open access: yesBiomolecules, 2022
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer, occurrence of cancer, or patient outcome. They may include germline or somatic genetic variants, epigenetic signatures, transcriptional changes, and proteomic ...
V. Sarhadi, G. Armengol
semanticscholar   +1 more source

Biomarkers in emergency medicine [PDF]

open access: yes, 2018
Researchers navigate the ocean of biomarkers searching for proper targets and optimal utilization of them. Emergency medicine builds up the front line to maximize the utility of clinically validated biomarkers and is the cutting edge field to test the ...
Cardelli, P., Hur, M., Somma, S. D.
core   +2 more sources

Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors

open access: yesBiomarker Research, 2023
Background Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint ...
Dingwei Ye   +16 more
doaj   +1 more source

NAFLD: Mechanisms, Treatments, and Biomarkers

open access: yesBiomolecules, 2022
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is growing in parallel with the obesity epidemic.
F. Nassir
semanticscholar   +1 more source

Conditional Screening for Ultra-high Dimensional Covariates with Survival Outcomes [PDF]

open access: yes, 2016
Identifying important biomarkers that are predictive for cancer patients' prognosis is key in gaining better insights into the biological influences on the disease and has become a critical component of precision medicine.
Hong, Hyokyoung Grace   +2 more
core   +3 more sources

Integration of Proteomics, Bioinformatics and Systems biology in Brain Injury Biomarker Discovery

open access: yesFrontiers in Neurology, 2013
Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes.
Joy eGuingab-Cagmat   +3 more
doaj   +1 more source

Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium

open access: yesNature Reviews Cardiology, 2022
Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and thromboembolic events, owing to excessive inflammation, endothelial cell activation and injury, platelet activation and hypercoagulability.
Diana A Gorog   +16 more
semanticscholar   +1 more source

The potential of pathological protein fragmentation in blood-based biomarker development for dementia – with emphasis on Alzheimer’s disease

open access: yesFrontiers in Neurology, 2015
The diagnosis of dementia is challenging and early stages are rarely detected limiting the possibilities for early interven-tion. Another challenge is the overlap in the clinical features across the different dementia types leading to difficulties in the
Dilek eInekci   +4 more
doaj   +1 more source

ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]

open access: yes, 2015
Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md   +7 more
core   +1 more source

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