Results 41 to 50 of about 1,714,833 (331)
Biomarkers of browning of white adipose tissue and their regulation during exercise- and diet-induced weight loss [PDF]
, 2016 Background: A hypothesis exists whereby an exercise- or dietary-induced negative energy balance reduces human subcutaneous white adipose tissue (scWAT) mass through the formation of brown-like adipocyte (brite) cells.
Andrea R Josse +48 more
core +2 more sources
Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]
, 2012 Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
AA Elgamal +58 more
core +3 more sources
Identification of prognostic and predictive biomarkers in high-dimensional data with PPLasso [PDF]
arXiv, 2022 In clinical trials, identification of prognostic and predictive biomarkers is essential to precision medicine. Prognostic biomarkers can be useful for the prevention of the occurrence of the disease, and predictive biomarkers can be used to identify patients with potential benefit from the treatment.
arxiv
ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]
, 2015 Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md +7 more
core +1 more source
Arthritis Research & Therapy, 2019 Background Pain is a debilitating symptom of rheumatoid arthritis (RA), caused by joint inflammation and cartilage and bone destruction. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat pain and inflammation in RA, but are not disease ...
Anna Katri +7 more
doaj +1 more source
Nonparametric empirical Bayes biomarker imputation and estimation [PDF]
arXiv, 2023 Biomarkers are often measured in bulk to diagnose patients, monitor patient conditions, and research novel drug pathways. The measurement of these biomarkers often suffers from detection limits that result in missing and untrustworthy measurements. Frequently, missing biomarkers are imputed so that down-stream analysis can be conducted with modern ...
arxiv
Biomarkers: a strategic tool in the assessment of environmental quality of coastal waters [PDF]
, 2007 Ecosystems are under the pressure of complex mixtures of contaminants whose effects are not always simple to assess. Biomarkers, acting as early warning signals of the presence of potentially toxic xenobiotics, are useful tools for assessing either ...
Bebianno, Maria João +4 more
core +1 more source
Epilepsia, 2013 SummaryA biomarker is defined as an objectively measured characteristic of a normal or pathologic biologic process. Identification and proper validation of biomarkers of epileptogenesis (the development of epilepsy) and ictogenesis (the propensity to generate spontaneous seizures) might predict the development of an epilepsy condition; identify the ...
Pitkänen, Asla +11 more
openaire +6 more sources
Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway
Journal of Experimental & Clinical Cancer Research, 2022 Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li +14 more
doaj +1 more source
Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]
, 2017 Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger +25 more
core +1 more source