Results 251 to 260 of about 116,047 (273)

Mechanical Remodeling of Nuclear Biomolecular Condensates

Physiology
Organism health relies on cell proliferation, migration, and differentiation. These universal processes depend on cytoplasmic reorganization driven notably by the cytoskeleton and its force-generating motors. Their activity generates forces that mechanically agitate the cell nucleus and its interior.
Giulia Soggia, Yasmin ElMaghloob, Annie-Kermen Boromangnaeva, Adel Al Jord   +3 more
openaire   +3 more sources

Dual function of biomolecular condensates

Nature Reviews Neurology, 2023
openaire   +2 more sources

Ionic Effect on the Microenvironment of Biomolecular Condensates

Journal of the American Chemical Society
Biomolecules such as proteins and RNA could organize to form condensates with distinct microenvironments through liquid-liquid phase separation (LLPS). Recent works have demonstrated that the microenvironment of biomolecular condensates plays a crucial role in mediating biological activities, such as the partition of biomolecules, and the subphase ...
Longchen Zhu, Yifei Pan, Ziyi Hua, Yu Liu, Xin Zhang   +4 more
openaire   +2 more sources

The purification of biomolecular condensates: Bottlenecks and strategies

Journal of Cell Biology
Biomolecular condensates are large assemblies of proteins and nucleic acids that form distinct compartments inside the cell without being surrounded by a membrane. They form through multivalent interactions, are not stereospecifically defined, and can scale with component addition.
Sylvain Tartier, Jihane Basbous, Séverine Boulon, Céline Verheggen, Edouard Bertrand   +4 more
openaire   +2 more sources

Frontiers in biomolecular condensate research

Nature Cell Biology, 2023
Mayr, C., Mittag, T., Tang, T., Wen, W., Zhang, H., Zhang, H.   +5 more
openaire   +3 more sources

A Framework for Understanding the Functions of Biomolecular Condensates Across Scales

Nature Reviews Molecular Cell Biology, 2021
Andrew S Lyon, Michael K. Rosen
exaly  

Introduction: Biophysics of biomolecular condensates

Protein Science, 2021
openaire   +2 more sources

The Role of Ordered Cooperative Assembly in Biomolecular Condensates

Nature Reviews Molecular Cell Biology, 2021
Alexander Dunn, Peter Tompa, Elgin Korkmazhan   +2 more
exaly  

RNA Contributions to the Form and Function of Biomolecular Condensates

Nature Reviews Molecular Cell Biology, 2021
Amy S. Gladfelter
exaly  

Targeting of Biomolecular Condensates to the Autophagy Pathway

Trends in Cell Biology, 2023
Pilong LI, Liang Ge
exaly