Out-of-equilibrium collective oscillation as phonon condensation in a model protein [PDF]
, 2018 In the first part of the present paper (theoretical), the activation of out-of-equilibrium collective oscillations of a macromolecule is described as a classical phonon condensation phenomenon. If a macromolecule is modeled as an open system, that is, it
Donato, Irene +12 more
core +4 more sources
Crosstalk between Biomolecular Condensates and Proteostasis
Cells, 2022 Proper homeostasis of the proteome, referred to as proteostasis, is maintained by chaperone-dependent refolding of misfolded proteins and by protein degradation via the ubiquitin-proteasome system and the autophagic machinery.
Emmanuel Amzallag, Eran Hornstein
doaj +1 more source
In Vitro Transcription-Translation in an Artificial Biomolecular Condensate [PDF]
, 2023 Biomolecular condensates are a promising platform for synthetic cell formation and constitute a potential missing link between the chemical and cellular stage of the origins of life.
André , Alain A. M. +6 more
core +2 more sources
A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network. [PDF]
, 2019 Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic enzymes robustly form structures,
Begovich, Kyle +5 more
core +3 more sources
Dielectric Metamaterials with Toroidal Dipolar Response [PDF]
, 2014 Toroidal multipoles are the terms missing in the standard multipole expansion; they are usually overlooked due to their relatively weak coupling to the electromagnetic fields.
Basharin, Alexey A. +6 more
core +5 more sources
The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex. [PDF]
, 2019 The inner centromere is a region on every mitotic chromosome that enables specific biochemical reactions that underlie properties, such as the maintenance of cohesion, the regulation of kinetochores and the assembly of specialized chromatin, that can ...
A Chakraborty +57 more
core +2 more sources
Micellization: A new principle in the formation of biomolecular condensates
Frontiers in Molecular Biosciences, 2022 Phase separation is a fundamental mechanism for compartmentalization in cells and leads to the formation of biomolecular condensates, generally containing various RNA molecules.
Tomohiro Yamazaki +3 more
doaj +1 more source
Counting the ions surrounding nucleic acids. [PDF]
, 2016 Nucleic acids are strongly negatively charged, and thus electrostatic interactions-screened by ions in solution-play an important role in governing their ability to fold and participate in biomolecular interactions.
Jacobson, David R, Saleh, Omar A
core +1 more source
Dynamical control enables the formation of demixed biomolecular condensates
Nature Communications, 2023 Cellular matter can be organized into compositionally distinct biomolecular condensates. For example, in Ashbya gossypii, the RNA-binding protein Whi3 forms distinct condensates with different RNA molecules.
Andrew Z. Lin +10 more
doaj +1 more source
Generic features of modulational instability in nonlocal Kerr media [PDF]
, 2001 The modulational instability (MI) of plane waves in nonlocal Kerr media is studied for a general, localized, response function. It is shown that there always exists a finite number of well-separated MI gain bands, with each of them characterised by a ...
Bang, Ole +3 more
core +2 more sources