Results 151 to 160 of about 11,629 (239)

Nitrile-aminothiol bioorthogonal near-infrared fluorogenic probes for ultrasensitive in vivo imaging

open access: yesNature Communications
Bioorthogonal chemistry-mediated self-assembly holds great promise for dynamic molecular imaging in living organisms. However, existing approaches are limited to nanoaggregates with ‘always-on’ signals, suffering from high signal-to-background ratio (SBR)
Weiping Xu   +4 more
doaj   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang   +9 more
wiley   +1 more source

Nanostructured Lipid Carriers Overcome the Low Immunogenicity of M2e Peptide via Surface Click Chemistry Conjugation, Improving the Anti‐M2e Antibody Response

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
1) Nanostructured lipid carriers efficiently vectorize low‐immunogenic M2e peptide. 2) M2e peptide conjugation via click chemistry preserves the peptide key epitopes. 3) Forty M2e peptides per nanoparticle are sufficient to induce robust immune responses.
Louis Bourlon   +7 more
wiley   +1 more source

Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications. [PDF]

open access: yesNanoscale Adv, 2021
Idiago-López J   +3 more
europepmc   +1 more source

Bioorthogonal chemistry in living animals [PDF]

open access: yesNational Science Review, 2017
Xinyuan Fan, Jie Li, Peng R. Chen
openaire   +1 more source

One‐Pot Ruthenium‐Catalyzed Synthesis of Benzyl/Allyl‐Halide Substituted (dihydro)naphthalenes via Radical Benzannulation

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
A one‐pot protocol to synthesize reactive benzyl‐ and allyl‐halide‐substituted (dihydro)naphthalenes from 2,3‐aryl‐1,3‐butadiene substrates and halogenated alkanes has been developed, using [Cp*RuCl(PPh3)2] as the catalyst. Mechanistic studies revealed an atom transfer radical addition and radical benzannulation sequence, followed by HCl elimination ...
Nicole S. van Leeuwen   +9 more
wiley   +1 more source

Bioorthogonal Chemistry for Pretargeted PET Imaging

open access: yes, 2013
Positron Emission Tomography (PET) is emerging as a powerful method for imaging cancer through the design and development of new radiotracers. Antibodies have promising properties as ligands for targeting cancer, as they have the advantage of displaying high affinity for their respective receptors.
openaire   +3 more sources

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