Results 151 to 160 of about 2,778,442 (233)
Treponema pallidum (T. pallidum) causes syphilis, a sexually transmitted disease that leads to multi‐organ complications and even death. The lack of technology for tracing live T. pallidum greatly impedes understanding of the pathogenesis of T. pallidum.
Jialin Huang +9 more
doaj +1 more source
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry. [PDF]
Liu L, Zhang D, Johnson M, Devaraj NK.
europepmc +1 more source
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
A Special Virtual Issue Celebrating the 2022 Nobel Prize in Chemistry for the Development of Click Chemistry and Bioorthogonal Chemistry. [PDF]
Bertozzi C.
europepmc +1 more source
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
Toward Ideal Proximity‐Driven Reactions in Chemical Biology [PDF]
Building on established principles of molecular templation, this perspective explores how molecular recognition can control chemical reactivity in space and time and outlines the design principles of an ideal proximity‐driven reaction for chemical biology.
Schauenburg D.
europepmc +2 more sources
Controlled Peptide Capture and Release in 3D‐Printed Multimaterial Microstructures
Two‐photon laser printing of 3D microstructures using a peptide‐containing ink is shown. The microstructures allow for controlled capture and release of target peptides through coiled‐coil interaction with the printed peptide inside the material. Based on these properties, orthogonal capture and stimuli‐mediated release possibilities inside printed ...
Niklas Schwegler +4 more
wiley +1 more source
A bioorthogonal chemistry approach to detect the K1 polysialic acid capsule in Escherichia coli. [PDF]
Rigolot V, Rossez Y, Biot C, Lion C.
europepmc +1 more source
Bioorthogonal chemistry in living animals [PDF]
Xinyuan Fan, Jie Li, Peng R. Chen
openaire +1 more source
Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source

