Site-Specific Fluorescent Labeling of Nascent Proteins on the Translating Ribosome [PDF]
, 2011 As newly synthesized proteins emerge from the ribosome, they interact with a variety of cotranslational cellular machineries that facilitate their proper folding, maturation, and localization.
Chandrasekaran, Sandhya +3 more
core +1 more source
Manipulating complex chromatin folding via CRISPR-guided bioorthogonal chemistry. [PDF]
Proc Natl Acad Sci U S A, 2022 Qin G, Yang J, Zhao C, Ren J, Qu X.
europepmc +1 more source
Bioorthogonal Chemistries for Glycoprofiling and Beyond
The FASEB Journal, 2012 The glycome is dynamically regulated during development and disease progression. The ability to detect changes in protein glycosylation, in tissue and serum samples as well as in vivo, is of considerable interest for biomarker identification and disease monitoring.
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Commentary on the role of polyoxometalates in nature cybernetic loop
Natural SciencesThe interplay between extraterrestrial, atmospheric, aqueous, interfacial, and hydrothermal processes is crucial for Earth's prebiotic chemistry. Volcanic terrains contain polyoxometalates (POMs).
Kirill Yu. Monakhov
doaj +1 more source
Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be "Switched Off" via Bioorthogonal Chemistry Inside Live Cells. [PDF]
J Am Chem Soc, 2023 Tallon AM +4 more
europepmc +1 more source
Erratum to: Bioorthogonal Chemistry—Introduction and Overview [PDF]
Topics in Current Chemistry, 2016 Thomas, Carell, Milan, Vrabel
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AggregateTreponema pallidum (T. pallidum) causes syphilis, a sexually transmitted disease that leads to multi‐organ complications and even death. The lack of technology for tracing live T. pallidum greatly impedes understanding of the pathogenesis of T. pallidum.
Jialin Huang +9 more
doaj +1 more source
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry. [PDF]
Nat Chem, 2022 Liu L, Zhang D, Johnson M, Devaraj NK.
europepmc +1 more source
A Special Virtual Issue Celebrating the 2022 Nobel Prize in Chemistry for the Development of Click Chemistry and Bioorthogonal Chemistry. [PDF]
ACS Cent Sci, 2023 Bertozzi C.
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Advanced Science, Volume 13, Issue 21, 13 April 2026.We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang +14 more
wiley +1 more source