Results 131 to 140 of about 11,629 (239)
Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
wiley +1 more source
Small‐Molecule Activation of mRNA Translation by Click‐to‐Release Reaction in Cells
A new method to control mRNA activity using bioorthogonal click‐to‐release reactions is presented. The 5′ cap is modified with a trans‐cyclooctene (TCO) that quickly reacts with hydroxyaryl‐tetrazines and efficiently releases the native cap 0. TCO‐capped mRNAs are initially translationally inactive but can be activated with non‐toxic, cell‐permeable ...
Tess Vosman +5 more
wiley +2 more sources
The future of bioorthogonal-chemistry for targeting of exosomes in precision medicine. [PDF]
Ullah M.
europepmc +1 more source
Bioorthogonal Chemistry in Biology and Medicine
Bioorthogonal chemistry and reactions developed from innovations in chemistry, having their excellent biocompatibility can be applied in various biological reactions. As these reactions, does not interfere with other reactions in the biological system, they can be used as excellent tools for tracking and studying dynamics of various biological ...
openaire +1 more source
Dual Cluster‐Surface Click Chemistries on Silver Nanoclusters
In this report, two new structures of clickable anion templated silver nanoclusters (NCs) equipped with azide functional groups capable of cluster surface click reactions are described. It is demonstrated for the first time the Staudinger–Bertozzi ligation and dual click reactions Staudinger–Bertozzi ligation‐strain‐promoted azide–alkyne cycloadditions
Carolina Vega Verduga +5 more
wiley +1 more source
Exploring Lignification Complexity in Plant Cell Walls with Airyscan Super-resolution Microscopy and Bioorthogonal Chemistry. [PDF]
Simon C +8 more
europepmc +1 more source
Das Dimer der Pyrrolysyl‐tRNA‐Synthetase zeigt im katalytischen Zyklus einen alternierenden Wirkmodus seiner Monomere, der durch die Belegung sekundärer Bindungsstellen an den Intermonomer‐Grenzflächen außerhalb der katalytischen Bindungsstelle realisiert wird.
Jessica Dröden +6 more
wiley +1 more source
The 2022 Nobel Prize in Chemistry for the development of click chemistry and bioorthogonal chemistry. [PDF]
Zaia J.
europepmc +1 more source
Chemical approaches to sphingolipid research [PDF]
Podeu consultar el llibre complet a: http://hdl.handle.net/2445 ...
Abad Saiz, José Luis +3 more
core
We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Tommaso Braga +2 more
wiley +1 more source

