Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells. [PDF]
Serfling R, Seidel L, Böttke T, Coin I.
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Recent Advances in Inverse-Electron-Demand Hetero-Diels–Alder Reactions of 1-Oxa-1,3-Butadienes [PDF]
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A powerful bioorthogonal toolbox boosting the development of immune theranostics. [PDF]
Liu S, Hua C, Li X, Yuan P, Xing B.
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Spatiotemporally controlled drug release via a click-release system utilizing mono-alkyl-hydroxylamine and cyclooctyne chemistry. [PDF]
Xu X +11 more
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Selenium nanoparticles with bioorthogonal targeting to boost CAR-cell therapy for colorectal cancer. [PDF]
Zhou J +13 more
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A Noncovalent Click-to-Release Strategy to Control Bond Cleavage and Prodrug Activation. [PDF]
Fu X +9 more
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Controlled intra- and extracellular localization of bioorthogonal polymeric nanozymes. [PDF]
Hirschbiegel CM +8 more
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Development of Three Alternative Strategies for the Binding of Cells to Functionalized DeepTip<sup>TM</sup> AFM Probes. [PDF]
Tabraue-Rubio R +9 more
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Investigating the bioorthogonality of isocyanides.
Nakao R +7 more
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Orthogonal bioorthogonal chemistries
Current Opinion in Chemical Biology, 2015Bioorthogonal reactions have long been used to examine individual biomolecules in living systems. Studies of multi-component networks demand not only reliable bioorthogonal chemistries, but also combinations of reactions that can be used in tandem. Such 'orthogonal bioorthogonal' transformations have been reported in recent years, and these chemistries
David M, Patterson, Jennifer A, Prescher
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