Results 41 to 50 of about 444 (111)

Isolation, Identification and Characterization of Two Novel Peptide Inhibitors of Dipeptidyl Peptidase 4 From Mung Bean (Vigna radiata) Protein Hydrolysate: Gastric Stability and Mechanistic Insight

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
The growing global burden of diabetes warrants search for natural, food‐derived bioactive molecules, including peptides. In this paper, dipeptidyl peptidase 4 (DPP4), a type 2 diabetes drug target,inhibitory peptides from the seed protein hydrolysates of mung bean (Vigna radiata) were studied.
Gaurav Srivastava, Dharmendra K. Maurya, Sahayog N. Jamdar, Akhilesh K. Verma   +3 more
wiley   +1 more source

Debittering and Masking Soy Peptides for Oral Consumption and Immune‐Boosting Function

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Soy peptides (SPs) have been extensively studied with an emphasis on their immune‐boosting effects and production‐associated bitterness. This associated bitterness affects SPs’ oral consumption despite their bioactivities. In this review, the immune‐boosting functions, factors affecting bitterness, and consumers’ perceptions of SPs are explored ...
Wei Li, Chaoling Wen, Opeyemi Joshua Olatunji, Chi Ching Lee, Tolulope Joshua Ashaolu, Anupama Bose   +5 more
wiley   +1 more source

Chia Seed Peptides Drive Food Quality Innovation Through Optimized Extraction, Compositional Insights, and Techno‐Functional Utility: A Review

Journal of Food Quality, Volume 2026, Issue 1, 2026.
Chia seed peptides (CSPs), liberated from defatted flour via strategic enzymatic hydrolysis, emerge as multifunctional ingredients that fundamentally transform food quality. Specifically, Alcalase and Flavourzyme proteases generate low molecular weight fractions possessing potent angiotensin‐converting enzyme (ACE) inhibition and broad pH solubility ...
Joachim Dotto Matondo, Seyed Mohammad Taghi Gharibzahedi   +1 more
wiley   +1 more source

Characterization and Identification of Potential Antioxidant, Antidiabetic, and Antihypertensive Peptides From Hydrolysates of Tenebrio molitor Flour and Its Protein Concentrate

Journal of Food Science, Volume 90, Issue 10, October 2025.
ABSTRACT Insects are recognized as a potential alternative source of proteins and have been studied in recent years as a substrate for enzymatic hydrolysis to obtain bioactive peptides. This study aimed to evaluate the production of hydrolysates with antioxidant, antidiabetic, and antihypertensive properties from mealworm (Tenebrio molitor) flour and ...
Francielle Miranda de Matos, Ruann Janser Soares de Castro   +1 more
wiley   +1 more source

Bioinformatics for circular economy research decision-making: A case study in obtaining bioactive peptides from Citrus sinensis peels via limonene synthase analysis

Sustainable Chemistry for the Environment
In the era of technology-driven research, bioinformatics is crucial for informed decision-making. Extracting orange essential oil, a key source of Limonene, offers a valuable opportunity.
Anelize Felicio Ramos, Aniela Pinto Kempka   +1 more
doaj   +1 more source

Anti‐Thrombotic Effect of Hemp Seed Peptides in Zebrafish by Dual Regulation of vegfr1 Signaling and Caspase‐3‐Mediated Apoptosis

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Characterize the thrombin‐inhibitory capacity of hemp seed peptides. Evaluate antithrombotic efficacy through hemodynamic and vascular parameters. Elucidate mechanisms via vegfr1 and caspase‐3 gene expression analysis. ABSTRACT This study aimed to investigate the antithrombotic activity of hemp seed peptides derived from trypsin hydrolysates and ...
Jie Shi, Jingyi Ge, Zhenghai Zhang, Lianhui Wei, Yan Dong, Guowei Li, Qingli Yang, Jing Pan, Yanru Ji   +8 more
wiley   +1 more source

Functional and Bioactive Benefits of Selected Microalgal Hydrolysates Assessed In Silico and In Vitro

Marine Drugs
BIOPEP-UWM, a peptide database, contains 5128 peptides from a myriad of resources. Five listed peptides are Angiotensin-I-converting enzyme (ACE-1; EC3.4.15.1) inhibitory peptides derived from a red alga, while two from Chlorella vulgaris have anti ...
Elena Aurino, Leticia Mora, Antonio Marzocchella, Christina M. Kuchendorf, Bärbel Ackermann, Maria Hayes   +5 more
doaj   +1 more source

GRU4ACE: Enhancing ACE inhibitory peptide prediction by integrating gated recurrent unit with multi‐source feature embeddings

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Accurate identification of angiotensin‐I‐converting enzyme (ACE) inhibitory peptides is essential for understanding the primary factor regulating the renin‐angiotensin system and guiding the development of new drug candidates. Given the inherent challenges in experimental processes, computational methods for in silico peptide identification ...
Saeed Ahmed, Nalini Schaduangrat, Pramote Chumnanpuen, Watshara Shoombuatong   +3 more
wiley   +1 more source

Revitalising Brewers' Spent Grains and Enriching With Biogenic Compounds Through the Fermentation of Fructophilic Lactic Acid Bacteria and Yeasts

Microbial Biotechnology, Volume 18, Issue 6, June 2025.
Non‐conventional starters (F. fructosus PL22 and W. anomalus GY1) enrich brewer's spent grain (BSG) portfolio of bioactive compounds. Fermented BSG showed antioxidant and antifungal activities and boosted keratinocyte proliferation, FLG expression, and wound healing.
Alessandro Stringari, Ali Zein Alabiden Tlais, Stefano Tonini, Daniela Pinto, Giorgia Mondadori, Pasquale Filannino, Raffaella Di Cagno, Marco Gobbetti   +7 more
wiley   +1 more source

In Silico Evaluation of Human α‐S1‐Casein, β‐Casein, and κ‐Casein as a Source of Bioactive Peptides

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Human caseins (α‐S1, β, and κ‐casein) represent a potential source of bioactive peptides with possible therapeutic applications, particularly for neonates. Due to the relevance of obtaining bioactive peptides, an in silico simulation of enzymatic hydrolysis with pepsin (pH > 2) was performed on these proteins using the PeptideCutter tool from Expasy ...
Diego Arturo Zavala Trejo, Blanca Rosa Aguilar Uscanga, Ariana Rodríguez Arreola, Esperanza González Quezada, Josué Raymundo Solís Pacheco, Anupama Bose   +5 more
wiley   +1 more source