Results 21 to 30 of about 4,616,011 (148)

Evaluation of the multifunctional dipeptidyl-peptidase IV and angiotensin converting enzyme inhibitory properties of a casein hydrolysate using cell-free and cell-based assays

Frontiers in Nutrition, 2023
The objective of the study was the evaluation of the potential pleiotropic effect of a commercial casein hydrolysate (CH). After an analysis of the composition, the BIOPEP-UWM database suggested that these peptides contained numerous sequences with ...
Jianqiang Li, Carlotta Bollati, Gilda Aiello, Martina Bartolomei, Fabrizio Rivardo, Giovanna Boschin, Anna Arnoldi, Carmen Lammi   +7 more
doaj   +1 more source

Bovine Milk Protein-Derived Preparations and Their Hydrolysates as Sources of ACE-Inhibitory, DPP-IV-Inhibitory, and Antioxidative Peptides Analyzed Using in Silico and in Vitro Protocols [PDF]

International Journal of Molecular Sciences
Anna Iwaniak, Justyna Zulewska, Małgorzata Darewicz   +2 more
exaly   +2 more sources

Hybrid Approach in the Analysis of Bovine Milk Protein Hydrolysates as a Source of Peptides Containing Di- and Tripeptide Bitterness Indicators

Polish Journal of Food and Nutrition Sciences, 2020
The aim of this study was to employ a hybrid approach combined with a fragmentomic idea of research used to analyze bovine milk protein hydrolysates as a source of peptides with a potential bitter taste.
Anna Iwaniak, Piotr Minkiewicz, Monika Hrynkiewicz, Justyna Bucholska, Małgorzata Darewicz   +4 more
doaj   +1 more source

Soybean (Glycine max) Protein Hydrolysates as Sources of Peptide Bitter-Tasting Indicators: An Analysis Based on Hybrid and Fragmentomic Approaches

Applied Sciences, 2020
The aim of this study was to analyze soybean proteins as sources of peptides likely to be bitter using fragmentomic and hybrid approaches involving in silico and in vitro studies.
Anna Iwaniak, Monika Hrynkiewicz, Piotr Minkiewicz, Justyna Bucholska, Małgorzata Darewicz   +4 more
doaj   +1 more source

In Silico and In Vitro Analyses of Angiotensin-I Converting Enzyme Inhibitory and Antioxidant Activities of Enzymatic Protein Hydrolysates from Taiwan Mackerel (Scomber australasicus) Steaming Juice

Foods, 2022
Mackerel (Scomber australasicus) steaming juice (MSJ) can be a good source of proteins. However, it is often treated as food waste during the canning process.
Fenny Crista A. Panjaitan, Ting-Yi Chen, Hao-Hsiang Ku, Yu-Wei Chang   +3 more
doaj   +1 more source

Identification and molecular mechanism of angiotensin-converting enzyme inhibitory peptides from Larimichthys crocea titin

Food Science and Human Wellness, 2020
This study aimed to identify novel ACEI peptides from Larimichthys crocea titin using in silico approaches and to clarify the molecular interaction mechanism.
Yue Fan, Zhipeng Yu, Wenzhu Zhao, Long Ding, Fuping Zheng, Jianrong Li, Jingbo Liu   +6 more
doaj   +1 more source

Prediction of ACE-I Inhibitory Peptides Derived from Chickpea (Cicer arietinum L.): In Silico Assessments Using Simulated Enzymatic Hydrolysis, Molecular Docking and ADMET Evaluation

Foods, 2022
Chickpea (Cicer arietinum L.) peptides have shown in vitro potential to inhibit the angiotensin I-converting enzyme (ACE-I). However, the potential molecular interactions between chickpea peptides (CP) and ACE-I as well as their ADMET (absorption ...
Jesús Gilberto Arámburo-Gálvez, Aldo Alejandro Arvizu-Flores, Feliznando Isidro Cárdenas-Torres, Francisco Cabrera-Chávez, Giovanni I. Ramírez-Torres, Lilian Karem Flores-Mendoza, Pedro Erick Gastelum-Acosta, Oscar Gerardo Figueroa-Salcido, Noé Ontiveros   +8 more
doaj   +1 more source

Development of Functional Soybean-Enriched Cheese: Identification of Novel Angiotensin-Converting Enzyme-Inhibitory and Predicted Dipeptidyl Peptidase IV-Related Peptides. [PDF]

Food Sci Nutr
This graphical abstract summarizes the development of soybean‐enriched hybrid cheese, its fermentation with proteolytic starter cultures, peptidomic profiling by LC–MS/MS, and the identification of milk‐ and soybean‐derived peptides with angiotensin‐converting enzyme‐inhibitory activity and predicted dipeptidyl peptidase IV‐related bioactivity ...
Kemal ME, Kemal M, Temiz H.
europepmc   +2 more sources

An integrated approach to the analysis of antioxidative peptides derived from Gouda cheese with a modified β-casein content

Scientific Reports, 2022
This study is the first to present an integrated approach involving in silico and in vitro protocols that was pursued to analyse an antioxidative potency of Gouda cheese with modified content of β-casein.
Anna Iwaniak, Damir Mogut, Piotr Minkiewicz, Justyna Żulewska, Małgorzata Darewicz   +4 more
doaj   +1 more source

In Silico Analysis of Individual Fractions of Bovine Casein as Precursors of Bioactive Peptides—Influence of Post-Translational Modifications

Applied Sciences, 2023
Bovine casein is one of the most known precursors of bioactive peptides among food proteins. Thus far, in silico investigations addressing casein have taken no account of the impact of modifications of amino acid residues on the feasibility of bioactive ...
Piotr Minkiewicz, Małgorzata Darewicz, Anna Iwaniak   +2 more
doaj   +1 more source