Results 1 to 10 of about 420 (93)

BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified.
Piotr Minkiewicz   +2 more
exaly   +5 more sources

BIOPEP-UWM Virtual—A Novel Database of Food-Derived Peptides with In Silico-Predicted Biological Activity

open access: yesApplied Sciences, 2022
The novel BIOPEP-UWM Virtual database is designed as a repository of peptide sequences whose bioactivity or taste information was the result of in silico predictions.
Piotr Minkiewicz   +2 more
doaj   +5 more sources

Prediction of the Potential of Food Proteins as Sources of Biopeptides Using BIOPEP-UWM Database

open access: yesProceedings
Peptides derived from food proteins exhibit a variety of bioactivities, such as the inhibition of angiotensin converting enzyme (ACE; EC 3.4.15.1), dipeptidyl peptidase IV (DPP4; EC 3.4.14.5), α-glucosidase (EC 3.2.1.20), α-amylase (EC 3.2.1.1), etc., as
Anna Iwaniak   +2 more
doaj   +4 more sources

Hybrid Approach in the Analysis of Bovine Milk Protein Hydrolysates as a Source of Peptides Containing Di- and Tripeptide Bitterness Indicators

open access: yesPolish Journal of Food and Nutrition Sciences, 2020
The aim of this study was to employ a hybrid approach combined with a fragmentomic idea of research used to analyze bovine milk protein hydrolysates as a source of peptides with a potential bitter taste.
Anna Iwaniak   +4 more
doaj   +3 more sources

Analysis of Structure–Activity Relationships of Food-Derived DPP IV-Inhibitory Di- and Tripeptides Using Interpretable Descriptors

open access: yesApplied Sciences, 2023
This study aimed to analyze the structural requirements for di- and tripeptides exhibiting a DPP IV-inhibitory effect. The sequences of 46 di- and 33 tripeptides, including their bioactivity (IC50; μM), were implemented from the BIOPEP-UWM database ...
Monika Hrynkiewicz   +4 more
doaj   +3 more sources

Plant-Derived Proteins and Peptides as Potential Immunomodulators [PDF]

open access: yesMolecules, 2023
The immune response of humans may be modulated by certain biopeptides. The present study aimed to determine the immunomodulatory potential of plant-derived food proteins and hydrolysates obtained from these proteins via monocatalytic in silico hydrolysis
Iwona Szerszunowicz, Szymon Kozicki
doaj   +2 more sources

Characteristics of Potential Protein Nutraceuticals of Plant Origin with Antioxidant Activity

open access: yesMolecules, 2020
This study used selected plant proteins and the tools available in the BIOPEP-UWM database to profile proteins and release antioxidant nutraceuticals from their primary structures. The frequency of the occurrence of fragments with antioxidant activity in
Iwona Szerszunowicz, Jan Kłobukowski
doaj   +3 more sources

Characteristics of Biopeptides Released In Silico from Collagens Using Quantitative Parameters

open access: yesFoods, 2020
The potential of collagens to release biopeptides was evaluated using the BIOPEP-UWM-implemented quantitative criteria including the frequency of the release of fragments with a given activity by selected enzyme(s) (AE), relative frequency of release of ...
Anna Iwaniak   +4 more
doaj   +3 more sources

Influence of the Casein Genotype on Goat Milk Bioactivity: An In Silico Analysis of the Casein Peptidome [PDF]

open access: yesMolecules
Goat caseins are highly polymorphic proteins that affect milk functional properties. In this study, an in silico approach was employed to analyze the influence of goat casein allelic variants on the quantity and bioactivity potential of peptides released
Aram Y. Rubio-Reyes   +4 more
doaj   +2 more sources

Mining anticoagulant peptides from Poecilobdella manillensis by peptidomics analysis [PDF]

open access: yesNatural Products and Bioprospecting
Thrombosis triggers various severe diseases, while antithrombotic drugs carry bleeding risks, making the development of novel natural anticoagulants a subject of widespread attention.
Han-xue Zheng   +6 more
doaj   +2 more sources

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