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In Silico Analysis of Individual Fractions of Bovine Casein as Precursors of Bioactive Peptides—Influence of Post-Translational Modifications

Applied Sciences, 2023
Bovine casein is one of the most known precursors of bioactive peptides among food proteins. Thus far, in silico investigations addressing casein have taken no account of the impact of modifications of amino acid residues on the feasibility of bioactive ...
Piotr Minkiewicz, Małgorzata Darewicz, Anna Iwaniak +2 more
doaj +3 more sources

Mining anticoagulant peptides from Poecilobdella manillensis by peptidomics analysis [PDF]

Natural Products and Bioprospecting
Thrombosis triggers various severe diseases, while antithrombotic drugs carry bleeding risks, making the development of novel natural anticoagulants a subject of widespread attention.
Han-xue Zheng +6 more
doaj +2 more sources

Unraveling bitter peptides in wheat protein hydrolysates [PDF]

Food Chemistry: Molecular Sciences
Wheat protein hydrolysates (WPHs) hold promise for functional food applications, but papain (EC 3.4.22.2)-mediated hydrolysis often results in undesirable bitterness and low yields of small peptides.
Wenmeng He +4 more
doaj +2 more sources

Macroalgal Peptides with Predicted α-Glucosidase Inhibitory Activity: Preparation and Molecular Docking [PDF]

Marine Drugs
This study investigated the α-glucosidase inhibitory potential of enzymatic/alkaline treatments from Palmaria palmata using different proteases and pairwise combinations thereof.
Sakhi Ghelichi +4 more
doaj +2 more sources

BIOPEP-UWM database — present and future

Current Opinion in Food Science
Anna Iwaniak +2 more
exaly +2 more sources

Bovine Milk Protein-Derived Preparations and Their Hydrolysates as Sources of ACE-Inhibitory, DPP-IV-Inhibitory, and Antioxidative Peptides Analyzed Using in Silico and in Vitro Protocols [PDF]

International Journal of Molecular Sciences
Iwaniak A +5 more
exaly +2 more sources

Machine learning screening of bile acid-binding peptides in a peptide database derived from food proteins

Scientific Reports, 2021
Bioactive peptides (BPs) are protein fragments that exhibit a wide variety of physicochemical properties, such as basic, acidic, hydrophobic, and hydrophilic properties; thus, they have the potential to interact with a variety of biomolecules, whereas ...
Kento Imai, Kazunori Shimizu, Hiroyuki Honda +2 more
doaj +1 more source

Metabolic Syndrome-Preventive Peptides Derived from Milk Proteins and Their Presence in Cheeses: A Review

Applied Sciences, 2020
The metabolic syndrome (MetS) is defined as the occurrence of diet-related diseases such as abdominal obesity, atherogenic dyslipidemia, hyperglycemia (insulin resistance) and hypertension.
Anna Iwaniak, Damir Mogut
doaj +1 more source

Multi-Bioactivity of Protein Digests and Peptides from Oat (Avena sativa L.) Kernels in the Prevention of the Cardiometabolic Syndrome

Molecules, 2022
The aim of this study was to characterize the digests and peptides derived from oat kernel proteins in terms of their major enzyme inhibitory activities related to the prevention of cardiometabolic syndrome.
Małgorzata Darewicz +4 more
doaj +1 more source

Evaluation of the multifunctional dipeptidyl-peptidase IV and angiotensin converting enzyme inhibitory properties of a casein hydrolysate using cell-free and cell-based assays

Frontiers in Nutrition, 2023
The objective of the study was the evaluation of the potential pleiotropic effect of a commercial casein hydrolysate (CH). After an analysis of the composition, the BIOPEP-UWM database suggested that these peptides contained numerous sequences with ...
Jianqiang Li +7 more
doaj +1 more source

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