Results 111 to 120 of about 5,435 (148)
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Biosynthesis of Biopterin by Rat Brain
Journal of Neurochemistry, 1982Abstract: A method for the determination of [14C]biopterin biosynthesis from [14C]guanosine‐5′‐triphosphate by a desalted preparation from rat striatum, based on sequential reverse‐phase and cation‐exchange high performance liquid chromatography, is described.
Gregory Kapatos +2 more
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Journal of the Chemical Society C: Organic, 1969
An unambiguous synthesis of biopterin [2-amino-6-(L-erythro-1,2-dihydroxypropyl)pteridin-4-(3H)-one] is described; based on an improved synthesis of L-neopterin. The synthesis yields biopterin, a naturally occurring pteridine, in a pure, crystalline form without recourse to chromatography. D-Biopterin and D-neopterin are also described.
B. P. Tong +2 more
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An unambiguous synthesis of biopterin [2-amino-6-(L-erythro-1,2-dihydroxypropyl)pteridin-4-(3H)-one] is described; based on an improved synthesis of L-neopterin. The synthesis yields biopterin, a naturally occurring pteridine, in a pure, crystalline form without recourse to chromatography. D-Biopterin and D-neopterin are also described.
B. P. Tong +2 more
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Physiological and clinical chemistry of biopterin
Medicinal Research Reviews, 1989Chimie, dosage de la biopterine. Biosynthese de la tetrahydrobiopterine. Role physiologique de la tetrahydrobiopterine comme cofacteur des monooxygenases necessitant la pterine.
Toshiharu Nagatsu +2 more
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Biopterin and neopterin in human saliva
Life Sciences, 1989Presence of biopterin and neopterin in human saliva was investigated by HPLC after iodine oxidation in acidic medium. Concentrations of biopterin and neopterin (M +/- SEM) were 1.271 +/- 0.254 and 0.358 +/- 0.075 ng per ml, respectively, in saliva of apparently healthy young male adults, ages 20 to 22 years (n = 9).
Setsuko Katoh +3 more
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Pteridine diuretics as biopterin antagonists
Biochemical Pharmacology, 1974Abstract A series of pteridines having varying degrees of diuretic activity were tested for their effects on the growth of the pteridine-requiring flagellate, Crithidia fasciculata . Inhibition of growth was correlated with diuretic activity insofar as compounds devoid of diuretic effects were uninhibitory and active inhibitors were also good to ...
George W. Kidder, Virginia C. Dewey
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ChemInform Abstract: PTERIDINES, LXXV. SYNTHESIS AND PROPERTIES OF BIOPTERIN AND BIOPTERIN ANALOGS
Chemischer Informationsdienst, 1985AbstractAus dem Desoxy‐arabinose‐hydrazon (II) und den Diaminen ( l) werden Biopterin ( 111a), dessen Dimethyl‐Derivat (IIIc) und Biolumazin (IIIb) hergestellt.
M. Kappel +2 more
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Talanta, 2008
Abstract An off-line photoirradiation LC fluorimetric method to determine tetrahydrobiopterin (BH4), by photogeneration of biopterin (BIO), is described, as an alternative way to the chemical oxidation procedure. To minimize the uncontrolled BH4 oxidation, due to environmental oxygen, an antioxidant, dithiothreitol (DTT), was used. The acidity of the
A. Muñoz de la Peña +3 more
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Abstract An off-line photoirradiation LC fluorimetric method to determine tetrahydrobiopterin (BH4), by photogeneration of biopterin (BIO), is described, as an alternative way to the chemical oxidation procedure. To minimize the uncontrolled BH4 oxidation, due to environmental oxygen, an antioxidant, dithiothreitol (DTT), was used. The acidity of the
A. Muñoz de la Peña +3 more
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Quantitation of total biopterin and tetrahydrobiopterin in plasma
Clinical Biochemistry, 2007To develop a reliable method for the determination of tetrahydrobiopterin and total biopterin in plasma.Modifications include blood collection and handling procedures.Collection of blood in the presence of 0.1% (w/v) dithiothreitol and waiting for 2-3 h before centrifugation are optimal for adequate quantitation of both pterins.For a reliable ...
Ans Voskuilen-Kooijman, Durk Fekkes
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Pteridine, LXXV. Synthese und Eigenschaften von Biopterin und Biopterin‐Analogen
Liebigs Annalen der Chemie, 1984AbstractDie Synthese von Biopterin (6), seinem 2‐N,N‐Dimethyl‐ (8) und 4‐ Thioxo‐Derivat (19) sowie von Biolumazin (7) wird beschrieben. Durch Umsetzung von Biopterin mit α‐Acetoxyisobuttersäurechlorid läß sich die Seitenkette zu 6‐(L‐threo‐2‐Acetoxy‐1‐chlorpropyl)pterin (10) modifizieren, das als Ausgangsmaterial fär weitere Derivatisierungen dienen ...
Mathias Kappel +2 more
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The Origin of Red Blood Cell Biopterin
Molecular Genetics and Metabolism, 1998Data are presented to support the hypothesis that the biopterin content of red blood cells arises during erythropoiesis. Only when the plasma concentration rises above the erythrocyte concentration of biopterin is there likely to be diffusion into the cell.
R. J. Leeming, S.K. Hall, Anne Green
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