Results 131 to 140 of about 2,873 (175)
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ChemInform Abstract: PTERIDINES, LXXV. SYNTHESIS AND PROPERTIES OF BIOPTERIN AND BIOPTERIN ANALOGS
Chemischer Informationsdienst, 1985AbstractAus dem Desoxy‐arabinose‐hydrazon (II) und den Diaminen ( l) werden Biopterin ( 111a), dessen Dimethyl‐Derivat (IIIc) und Biolumazin (IIIb) hergestellt.
M. KAPPEL, R. MENGEL, W. PFLEIDERER
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Screening for Biopterin Disorders in PKU
Pediatrics, 1980It is now recognized (Pediatrics 65:806, 1980) that a small proportion of cases of phenylketonuria (PKU) may be due to abnormalities in the metabolism of biopterin. These cases do not respond to the restriction of dietary phenylalanine, but may be benefited by neurotransmitter replacement therapy. A specific diagnosis is therefore desirable.
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Journal of the Chemical Society C: Organic, 1969
An unambiguous synthesis of biopterin [2-amino-6-(L-erythro-1,2-dihydroxypropyl)pteridin-4-(3H)-one] is described; based on an improved synthesis of L-neopterin. The synthesis yields biopterin, a naturally occurring pteridine, in a pure, crystalline form without recourse to chromatography. D-Biopterin and D-neopterin are also described.
K. J. M. Andrews +2 more
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An unambiguous synthesis of biopterin [2-amino-6-(L-erythro-1,2-dihydroxypropyl)pteridin-4-(3H)-one] is described; based on an improved synthesis of L-neopterin. The synthesis yields biopterin, a naturally occurring pteridine, in a pure, crystalline form without recourse to chromatography. D-Biopterin and D-neopterin are also described.
K. J. M. Andrews +2 more
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A differential microdetermination for the various forms of biopterin
Analytical Biochemistry, 1978Abstract Conditions for the quantitative oxidation and destruction of tetrahydrobiopterin and quinoid dihydrobiopterin and the separation of biopterin from its reduced forms by ECTEOLA-Sephadex column chromatography are described. A procedure for the quantitation of tetrahydrobiopterin plus quinoid dihydrobiopterin, 7,8-dihydrobiopterin, and ...
T, Fukushima +3 more
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Biopterin cofactor and monoamine-synthesizing monooxygenases
Neurochemistry International, 1983The activities of three pterin-requiring monooxygenases, phenylalanine hydroxylase, tyrosine hydroxylase and tryptophan hydroxylase, are regulated by the level of the pterin cofactor, (6R)- l -erythro- tetrahydrobiopterin , which is synthesized from guanosine triphosphate (GTP).
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Biopterin metabolism in patients with malignant syndrome
Parkinsonism & Related Disorders, 2003We examined the autopsied brains of two parkinsonian patients who had malignant syndrome (MS). Neopterin and biopterin contents, and GTP cyclohydrolase I activity were measured in various region of the brain. We found relatively higher GTP cyclohydrolase I activities in the hypothalamus compared with other regions of the brain from patients with MS ...
H. Ichinose +7 more
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Synthesis of biopterin and related pterin glycosides
IUBMB Life, 2013AbstractCertain pterins having a hydroxyalkyl side chain at C‐6 have been found as glycosidic forms in certain prokaryotes, such as 2′‐O‐(α‐D‐glucopyranosyl)biopterin from various kinds of cyanobacteria, and limipterin from a green sulfur photosynthetic bacterium.
Tadashi, Hanaya, Hiroshi, Yamamoto
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Hyperphenylalaninaemia caused by defects in biopterin metabolism
Journal of Inherited Metabolic Disease, 1985AbstractThe hepatic phenylalanine hydroxylating system consists of three essential components, phenylalanine hydroxylase, dihydropteridine reductase and the non‐protein coenzyme, tetrahydrobiopterin. The reductase and the pterin coenzyme are also essential components of the tyrosine and tryptophan hydroxylating systems.
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Progress in Phenylketonuria: Defects in the Metabolism of Biopterin
Pediatrics, 1980Although progress in a major biological frontier, the neurosciences, has been both rapid and broadly based, it has offered little to the practical pediatrician. Some recent reports may forecast a change. Careful study of an old subject, phenylketonuria (PKU), has opened up a new area of research that has great potential significance ...
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Reindarstellung von Biopterin und 7-Biopterin
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1962H. Rembold, H. Metzger
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