Dystonia and Biopterin Deficiency
Five patients with childhood dystonia associated with reduced CSF biopterin, responsive to levodopa, and characterized by diurnal and exertional variation are reported from the Developmental and Metabolic Neurology Branch, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD.
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Abstract Aim We aimed to test the hypothesis that a high‐salt diet (HS) impairs NO signaling in kidney microvascular endothelial cells through a histone deacetylase 1 (HDAC1)‐dependent mechanism. Methods Male Sprague Dawley rats were fed normal salt diet (NS; 0.49% NaCl) or HS (4% NaCl) for 2 weeks. NO signaling was assessed by measuring L‐NAME induced
Luke S. Dunaway +11 more
wiley +1 more source
Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth. [PDF]
Chuaiphichai S +16 more
europepmc +1 more source
Radioimmunoassay for biopterin.
Toshiharu NAGATSU +9 more
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Associations of Biopterins and ADMA with Vascular Function in Peripheral Microcirculation from Patients with Chronic Kidney Disease. [PDF]
Arefin S +4 more
europepmc +1 more source
Metabolite diversity of Microcystis strains shows tight correspondence to genotype and may contribute to ecotype specificities. [PDF]
Huré A +9 more
europepmc +1 more source
Tetrahydrobiopterin in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Friend or Foe? [PDF]
Rahman AFMT +5 more
europepmc +1 more source
Transcriptional regulation of the GTP cyclohydrolase I gene via the NF-κB pathway by bacterial and viral immune stimulants. [PDF]
Ozawa M +6 more
europepmc +1 more source
Biopterin-Responsive Hyperphenylalaninemia
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