Results 171 to 180 of about 96,256 (296)

Compression bioreactor for cultured meat. [PDF]

Curr Res Food Sci
Chiu KH, Vogel S, Schillberg S, Ngwa CJ.
europepmc   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

High-solids ethanol production from waste paper through consolidated bioprocessing using advanced Saccharomyces cerevisiae strains. [PDF]

Bioprocess Biosyst Eng
Naudé JE, Rorke DCS, Görgens JF, van Rensburg E.   +3 more
europepmc   +1 more source

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

Biotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera, Ivan Gajic, Praveen Kusumanchi, Angela Andaluz, Gabrielle Dela Pena, Clifford A. Froelich, Elizabeth Higgins, Jennifer Johnston, Seyed Pouria Motevalian   +8 more
wiley   +1 more source

Characterisation of metabolic burden in Pseudomonas putida reveals precursor limitation in heterologous lycopene production. [PDF]

Microb Cell Fact
Meiners C, Hermann L, Stoja M, Kremling A, Pflüger-Grau K.   +4 more
europepmc   +1 more source

Regenerative perfusion bioreactor for biologics production with lower COGs

Biotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne, Dohyun Park, Hourieh Ahi, Jaeweon Lee, Seongkyu Yoon, Jongyoon Han   +5 more
wiley   +1 more source

Impact of single‐use bioreactor bag materials on Spodoptera frugiperda cell expansion for recombinant adeno‐associated virus manufacturing

Biotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus production for gene therapy applications commonly relies on the Spodoptera frugiperda 9 (Sf9) baculovirus infection platform. The process encompasses cell expansion from flasks through intermediate‐scale bioreactors to large‐scale production.
Min Tae Park, Seyed Pouria Motevalian
wiley   +1 more source

Valorization of Miscanthus × giganteus hydrolysates into heme-enriched yeast biomass and extract using xylose-fermenting Saccharomyces cerevisiae. [PDF]

Bioresour Bioprocess
Jung SC, Oh H, Kim S, Singh S, Singh V, Kim SR, Lu T, Koh HG, Jin YS.   +8 more
europepmc   +1 more source

Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy

Carbon Energy, EarlyView.
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie, Jia Ouyang, Manu Suvarna, Xiangzhou Yuan, Matthew R. Hill, Uwe Bornscheuer, Huiyan Zhang, Yong Sik Ok   +7 more
wiley   +1 more source

Cell-retention for lipid production in continuous Schizochytrium limacinum SR21 cultures fed with dark fermentation effluent. [PDF]

Bioresour Bioprocess
Täuber S, Ackermann L, Schittkowski H, Neubauer P, Junne S.   +4 more
europepmc   +1 more source