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Genotoxicity Integration into Bioprocess Optimization Reveals Progressive DNA Damage During Bioreactor Expansion of Adipose-Derived Stem Cells. [PDF]
Int J Mol SciSimão VA +7 more
europepmc +1 more source
Automated and scalable expansion of human liver organoids for translational applications. [PDF]
J Transl MedTen Dam MJM +8 more
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Current Opinion in Plant Biology, 2004
The production of recombinant proteins in moss bioreactors provides all of the benefits of molecular farming in plants but avoids many plant-specific disadvantages, such as the genetic instability of de-differentiated cells in suspension culture or the lack of containment during field production.
Decker, Eva L., Reski, Ralf
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The production of recombinant proteins in moss bioreactors provides all of the benefits of molecular farming in plants but avoids many plant-specific disadvantages, such as the genetic instability of de-differentiated cells in suspension culture or the lack of containment during field production.
Decker, Eva L., Reski, Ralf
openaire +3 more sources
International Journal of Biochemistry, 1994
1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne +6 more
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1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne +6 more
openaire +2 more sources
2013
Lab-scale stirred-tank bioreactors (0.2-20 l) are used for fundamental research on animal cells and in process development and troubleshooting for large-scale production. In this chapter, different configurations of bioreactor systems are shortly discussed and setting up these different configurations is described.
Martens, D.E. +2 more
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Lab-scale stirred-tank bioreactors (0.2-20 l) are used for fundamental research on animal cells and in process development and troubleshooting for large-scale production. In this chapter, different configurations of bioreactor systems are shortly discussed and setting up these different configurations is described.
Martens, D.E. +2 more
openaire +3 more sources
2018
In landfill, the control of degradable organics and related environmental impacts may be achieved by means of a series of options, including avoidance of putrescible fraction in landfilled waste (separate collection), prestabilization of waste prior to landfilling, in situ treatment to enhance biodegradation during landfilling and/or the aftercare ...
Raffaello Cossu, Valentina Grossule
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In landfill, the control of degradable organics and related environmental impacts may be achieved by means of a series of options, including avoidance of putrescible fraction in landfilled waste (separate collection), prestabilization of waste prior to landfilling, in situ treatment to enhance biodegradation during landfilling and/or the aftercare ...
Raffaello Cossu, Valentina Grossule
openaire +1 more source
Plant Cell Reports, 2005
Microalgae already serve as a major natural source of valuable macromolecules including carotenoids, long-chain polyunsaturated fatty acids and phycocolloids. As photoautotrophs, their simple growth requirements make these primitive plants potentially attractive bioreactor systems for the production of high-value heterologous proteins.
Walker, Tara L. +3 more
openaire +5 more sources
Microalgae already serve as a major natural source of valuable macromolecules including carotenoids, long-chain polyunsaturated fatty acids and phycocolloids. As photoautotrophs, their simple growth requirements make these primitive plants potentially attractive bioreactor systems for the production of high-value heterologous proteins.
Walker, Tara L. +3 more
openaire +5 more sources
2010
Along with the rapid development of life science, great attention has been increasingly given to the biotechnological products of cell cultivation technology. In the course of industrialization, bioreactor and bioproduct separation techniques are the two essential technical platforms.
Siliang, Zhang +4 more
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Along with the rapid development of life science, great attention has been increasingly given to the biotechnological products of cell cultivation technology. In the course of industrialization, bioreactor and bioproduct separation techniques are the two essential technical platforms.
Siliang, Zhang +4 more
openaire +2 more sources
Current Opinion in Biotechnology, 1997
Recent papers have described new bioreactor designs. Most innovations addressed either oxygen transfer, shear induced by stirring, control of water activity in organic phase systems or waste biotreatment. Innovations made during the past year were reported in mainly three areas: bioreactor designs for increases in oxygen transfer and decreases in shear
, Deshusses +3 more
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Recent papers have described new bioreactor designs. Most innovations addressed either oxygen transfer, shear induced by stirring, control of water activity in organic phase systems or waste biotreatment. Innovations made during the past year were reported in mainly three areas: bioreactor designs for increases in oxygen transfer and decreases in shear
, Deshusses +3 more
openaire +2 more sources