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Generation of Current Good Manufacturing Practices-Grade Mesenchymal Stromal Cell-Derived Extracellular Vesicles Using Automated Bioreactors [PDF]
BiologyInterest in Current Good Manufacturing Practices (cGMP)-grade extracellular vesicles (EVs) is expanding. Some obstacles in this new but rapidly growing field include a lack of standardization and scalability.
Elani F. Wiest, Abba C. Zubair
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Frontiers in Bioengineering and Biotechnology, 2021 Cell-based therapies involving the delivery of adipose-derived stromal cells (ASCs) on decellularized adipose tissue (DAT) scaffolds are a promising approach for soft tissue augmentation and reconstruction. Our lab has recently shown that culturing human
Tim Tian Y. Han +7 more
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Polish Achievements in Bioactive Compound Production From In Vitro Plant Cultures
Acta Societatis Botanicorum Poloniae, 2022 Plant cell and organ cultures are potential sources of valuable secondary metabolites that can be used as food additives, nutraceuticals, cosmeceuticals, and pharmaceuticals.
Agnieszka Pietrosiuk +18 more
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Bioreactor scalability: laboratory-scale bioreactor design influences performance, ecology, and community physiology in expanded granular sludge bed bioreactors [PDF]
, 2017 Studies investigating the feasibility of new, or improved, biotechnologies, such as wastewater treatment digesters, inevitably start with laboratory-scale trials.
Christopher Quince +7 more
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Frontiers in Cell and Developmental Biology, 2021 Bioreactor systems are built as controlled environments for biological processes and utilized in the field of tissue engineering to apply mechanical, spatial, and chemical cues to developing tissue grafts.
Sarah M. Somers +6 more
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Generation of an in vitro model of the outer annulus fibrosus‐cartilage interface
JOR Spine, 2020 Current treatments for degenerative disc disease do not restore full biological functionality of the intervertebral disc (IVD). As a result, regenerative medicine approaches are being developed to generate a biological replacement that when implanted ...
Jasmine E. Chong +2 more
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Frontiers in Bioengineering and Biotechnology, 2022 Since their first use in the 1930s, shake flasks have been a widely used bioreactor type for screening and process development due to a number of advantages.
Sven Hansen +5 more
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Bioreactors landfills: comparison and kinetics of the different systems [PDF]
, 2018 The need for more sustainable landfilling has increased interest in bioreactor landfills as a suitable tool for optimising degradation processes. Bioreactors can be categorised as follows: anaerobic, aerobic, semi aerobic and hybrid.
Cossu, Raffaello +3 more
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A Tissue Engineering product development pathway [PDF]
, 2012 Tissue engineering is a field of inquiry and research that uses engineering techniques and principles of biological sciences to develop functional substitutes for reconstruction of damaged organs.
Falvo D'Urso Labate, Giuseppe Vittorio Ugo
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Plants, 2023 At present, most precious compounds are still obtained by plant cultivation such as ginsenosides, glycyrrhizic acid, and paclitaxel, which cannot be easily obtained by artificial synthesis.
Baoyu Ji +7 more
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