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Generation of Current Good Manufacturing Practices-Grade Mesenchymal Stromal Cell-Derived Extracellular Vesicles Using Automated Bioreactors [PDF]
BiologyInterest in Current Good Manufacturing Practices (cGMP)-grade extracellular vesicles (EVs) is expanding. Some obstacles in this new but rapidly growing field include a lack of standardization and scalability.
Elani F. Wiest, Abba C. Zubair
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Transgenic animal bioreactors. [PDF]
Transgenic research, 2000 The production of recombinant proteins is one of the major successes of biotechnology. Animal cells are required to synthesize proteins with the appropriate post-translational modifications. Transgenic animals are being used for this purpose. Milk, egg white, blood, urine, seminal plasma and silk worm cocoon from transgenic animals are candidates to be
L. M. Houdebine
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Frontiers in Bioengineering and Biotechnology, 2021 Cell-based therapies involving the delivery of adipose-derived stromal cells (ASCs) on decellularized adipose tissue (DAT) scaffolds are a promising approach for soft tissue augmentation and reconstruction. Our lab has recently shown that culturing human
Tim Tian Y. Han +7 more
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Polish Achievements in Bioactive Compound Production From In Vitro Plant Cultures
Acta Societatis Botanicorum Poloniae, 2022 Plant cell and organ cultures are potential sources of valuable secondary metabolites that can be used as food additives, nutraceuticals, cosmeceuticals, and pharmaceuticals.
Agnieszka Pietrosiuk +18 more
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Frontiers in Cell and Developmental Biology, 2021 Bioreactor systems are built as controlled environments for biological processes and utilized in the field of tissue engineering to apply mechanical, spatial, and chemical cues to developing tissue grafts.
Sarah M. Somers +6 more
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Frontiers in Bioengineering and Biotechnology, 2022 Since their first use in the 1930s, shake flasks have been a widely used bioreactor type for screening and process development due to a number of advantages.
Sven Hansen +5 more
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Bioreactor scalability: laboratory-scale bioreactor design influences performance, ecology, and community physiology in expanded granular sludge bed bioreactors [PDF]
, 2017 Studies investigating the feasibility of new, or improved, biotechnologies, such as wastewater treatment digesters, inevitably start with laboratory-scale trials.
Christopher Quince +7 more
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Generation of an in vitro model of the outer annulus fibrosus‐cartilage interface
JOR Spine, 2020 Current treatments for degenerative disc disease do not restore full biological functionality of the intervertebral disc (IVD). As a result, regenerative medicine approaches are being developed to generate a biological replacement that when implanted ...
Jasmine E. Chong +2 more
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Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview
Metabolites, 2022 The Rubia genus includes major groups of medicinal plants such as Rubia cordifolia, Rubia tinctorum, and Rubia akane. They contain anthraquinones (AQs), particularly alizarin and purpurin, which have pharmacological effects that are anti-inflammatory ...
Hosakatte Niranjana Murthy +3 more
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Plants, 2022 Current breeding programs aim to increase the number of ink-tolerant chestnut trees using vegetative propagation of selected genotypes. However, the commercial vegetative propagation of chestnut species is still a bottleneck for the forest industry ...
Diego Gago +6 more
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