Results 101 to 110 of about 6,100 (218)
THE FEATURES OF THE PREDICTIVE DISSOLUTION TESTING (REVIEW)
Разработка и регистрация лекарственных средств, 2019 Dissolution test plays an important role at different levels of the development and manufacturing drugs as one of the major quality control tools and an integral part of In vitro tests in the study of drug release from the developed dosage forms. Article
R. I. Moustafine +2 more
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Mechanistic Studies of Drug Dissolution Testing : Implications of solid phase properties and in vivo prognostic media [PDF]
, 2010 Drug absorption after oral administration requires that the drug first dissolves into gastro-intestinal tract liquids. In vivo dissolution of a drug is affected by physiological and drug-related physicochemical factors.
Lehto, Paula
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Разработка и регистрация лекарственных средств, 2019 The results of Indomethacin release from the oral drug delivery systems based on interpolymer complexes with Eudragit® copolymers are presented.
A. V. Sitenkova (Bukhovets) +2 more
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Kaempferol-Phospholipid Complex: Formulation, and Evaluation of Improved Solubility, In Vivo Bioavailability, and Antioxidant Potential of Kaempferol [PDF]
, 2016 The current work describes the formulation and evaluation of a phospholipid complex of kaempferol toenhance the latter’s aqueous solubility, in vitro dissolution rate, in vivo antioxidant and hepatoprotectiveactivities, and oral bioavailability.
Anand, Sridhar +5 more
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Design of Biopolymer‐Coated Gold Nanorods as Biorelevant Photothermal Agents
Macromolecular Rapid CommunicationsAbstractGold nanorods (AuNRs) are emerging metallic nanoparticles utilized to generate heat for photothermal therapy (PTT) in cancer. The tunable plasmonic properties of AuNRs make them a remarkable candidate for hyperthermia. However, the cytotoxicity of AuNRs limits its biological applicability due to the existence of cetyltrimethylammonium bromide ...
Yağmur Zengin, Damla Kelle, Banu Iyisan
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Electrochemical C−H deuteration of pyridine derivatives with D2O
Nature CommunicationsHerein, we develop a straightforward, metal-free, and acid-/base-free electrochemical C4-selective C − H deuteration of pyridine derivatives with economic and convenient D2O at room temperature.
Zhiwei Zhao +5 more
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A REVIEW ON DEVELOPMENT OF BIORELEVANT DISSOLUTION MEDIUM
Journal of Drug Delivery and Therapeutics, 2014 Dissolution testing is a valuable tool that provides key information about bioavailability or bioequivalency as well as batch to batch consistency of drug. Since the number of poorly soluble drug is increasing, the selection of adequate dissolution test for these becomes more and more important. Biorelevant is a term, used to describe a medium that has
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Разработка и регистрация лекарственных средствThe use of biorelevant dissolution media makes it possible to reproduce conditions as in the human gastrointestinal tract. This expands the capabilities of laboratories involved in the analysis of solid dosage forms and allows obtaining physiologically ...
article Editorial
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DISSOLUTION MEDIA USED IN DEVELOPMENT AND QUALITY CONTROL OF DRUGS
Разработка и регистрация лекарственных средств, 2019 The main dissolution media recommended for the Dissolution test in Russia and abroad are represented in the review. Possible applications of biorelevant media and media with surfactants are also shown.
O. V. Druzhininskaya, I. E. Smekhova
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The Astrophysical JournalOxygen-containing complex organic molecules are key precursors to biorelevant compounds fundamental for the origins of life. However, the untangling of their interstellar formation mechanisms has just scratched the surface, especially for oxygen ...
Jia Wang +3 more
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