Results 71 to 80 of about 17,248,582 (189)
ChemElectroChem, Volume 13, Issue 13, 2 July 2026.The efficient electrochemical synthesis of iodinated carbonyl compounds, valuable building blocks, is reported. The method relies on the controlled generation of electrophilic iodine species from simple and inexpensive iodide salts under mild electrochemical conditions, enabling excellent compatibility with aldehydes bearing sensitive functional groups.
Biswadeep Manna +6 more
wiley +1 more source
Pharmaceutics, 2020 The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine.
Alexandra Teleki +2 more
doaj +1 more source
Dissolution Behavior of Flufenamic Acid in Heated Mixtures with Nanocellulose
Molecules, 2020 Flufenamic acid (FFA) is a problem drug that has up to eight different polymorphs and shows poor solubility. Variability in bioavailability has been reported in the past resulting in limited use of FFA in the oral solid dosage form.
Athanasios Mantas, Albert Mihranyan
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Advanced Science, Volume 13, Issue 36, 29 June 2026.The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko +11 more
wiley +1 more source
Evaluating the fed state impact on drug solubility and absorption : a biorelevant in vitro approach [PDF]
Biopharmaceutics, which studies the relationship between a drug's physical, chemical, biological, and pharmacological properties and its dosage form, is essential for studying and optimising oral formulations.
Silva, Maria Inês
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DISSOLUTION MEDIA USED IN DEVELOPMENT AND QUALITY CONTROL OF DRUGS
Разработка и регистрация лекарственных средств, 2019 The main dissolution media recommended for the Dissolution test in Russia and abroad are represented in the review. Possible applications of biorelevant media and media with surfactants are also shown.
O. V. Druzhininskaya, I. E. Smekhova
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ADMET and DMPKBackground and purpose: The evaluation of micellization parameters of surfactants that aggregate gradually, such as bile salts, is not trivial. In this work, different probes and data treatment models are tested to set up an analytical method based on ...
Susana Amézqueta +3 more
doaj +1 more source
Applications of USP apparatus 3 in assessing the in vitro release of solid oral dosage forms
Brazilian Journal of Pharmaceutical Sciences, 2015 USP Apparatus 3 (reciprocating cylinder) is a very versatile device for the in vitro assessment of release characteristics of solid oral dosage forms, because it enables the product to be subjected to different dissolution media and agitation speeds in a
Bianca Ramos Pezzini +3 more
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ChemMedChem, Volume 21, Issue 9, 14 May 2026.From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk +1 more
wiley +1 more source
THE FEATURES OF THE PREDICTIVE DISSOLUTION TESTING (REVIEW)
Разработка и регистрация лекарственных средств, 2019 Dissolution test plays an important role at different levels of the development and manufacturing drugs as one of the major quality control tools and an integral part of In vitro tests in the study of drug release from the developed dosage forms. Article
R. I. Moustafine +2 more
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