Results 61 to 70 of about 4,013 (240)
Разработка и регистрация лекарственных средств, 2021 Introduction. The presence of biologically active substances in the extract from the roots of turmeric extract (Curcuma longa L.) makes it reasonable and makes it possible to predict their effectiveness in pathological conditions caused by oxidative ...
O. A. Gizinger, A. A. Khisamova
doaj +1 more source
Variable-focus microscopy and UV surface dissolution imaging as complementary techniques in intrinsic dissolution rate determination [PDF]
, 2017 This work reports a novel approach to the assessment of the surface properties of compacts used in Surface Dissolution Imaging (SDI). SDI is useful for determining intrinsic dissolution rate (IDR), an important parameter in early stage drug development ...
Asare-Addo, Kofi +6 more
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Pharmaceutics, 2023 A strategy followed to integrate in vitro solubility and permeability data into a PBBM model to predict the food effect of a BCS IV zwitterionic drug (GSK3640254) observed in clinical studies is described.
Konstantinos Stamatopoulos +6 more
doaj +1 more source
Modelling the impact of atherosclerosis on drug release and distribution from coronary stents [PDF]
, 2015 Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart disease, there remains considerable scope for the development of enhanced designs which address some of the limitations of existing devices.
A Neubert +80 more
core +2 more sources
Study of the impact of different salts on the intrinsic dissolution rate of pharmaceutical compounds [PDF]
, 2017 The intrinsic dissolution rate (IDR) of a free base and its four salts were investigated with the aim of selecting the salt with the best dissolution performance.
Box, Karl +3 more
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Can biorelevant media be simplified by using SLS and tween 80 to replace bile compounds? [PDF]
, 2013 In the scientific literature, the use of a surfactant is recommended for both designing quality control tests for water insoluble or sparingly water soluble drugs and for predicting the bioavailability of drugs from various types of formulations.
Klein, Sandra, Taupitz, Thomas
core
Pharmaceutical Science without borders: The 8th APS International PharmSci 2017 [PDF]
, 2017 The Academy of Pharmaceutical Sciences (APSGB) is delighted to partner with the British Journal of Pharmacy to publish key abstracts of posters presented at this year’s APS PharmSci Conference held at the University of Hertfordshire 5th to 7th September ...
Wahlich, John
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Advanced Science, EarlyView.The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko +11 more
wiley +1 more source
Site selective reading of epigenetic markers by a dual-mode synthetic receptor array. [PDF]
, 2017 Variably functionalized self-folding deep cavitands form an arrayed, fluorescent indicator displacement assay system for the detection of post-translationally modified (PTM) histone peptides.
Bardeen, Christopher J +8 more
core +2 more sources
Advanced NanoBiomed Research, EarlyView.Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro +3 more
wiley +1 more source