Results 61 to 70 of about 17,248,582 (189)
Enhanced Dissolution of Naproxen by Combining Cocrystallization and Eutectic Formation
Improving dissolution properties of active pharmaceutical ingredients (APIs) is a critical step in drug development with the increasing occurrence of sparingly soluble APIs.
Hakyeong Kim, Soeun Jang, Il Won Kim
doaj +1 more source
The dissolution test in biorelevant media as a prognostic tool for modeling of drug behavior in vivo [PDF]
The review deals with the modern tool for modeling of drug behavior in vivo, - the dissolution test in biorelevant media, imitating gastrointestinal fluids. The formulations and preparation methods of fasted state simulation intestinal fluid, FaSSIF and fed state simulation intestinal fluid, FeSSIF, are defined.
G V, Ramenskaia +3 more
openaire +2 more sources
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu +5 more
wiley +1 more source
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro +3 more
wiley +1 more source
Feedback on the proposal for a regulation establishing a common framework for media services in the internal market (European Media Freedom Act) and amending Directive 2010/13/EU [PDF]
With this contribution, the Centre for Media Pluralism and Media Freedom (CMPF) at the European University Institute offers a feedback to some aspects of the Proposal for a Regulation of the European Parliament and the Council establishing a common ...
Centre for Media Pluralism and Media Freedom
core +1 more source
BIORELEVANT DISSOLUTION MEDIA: ITS CURRENT STATUS AND FUTUTRE PERSPECTIVES [PDF]
The landscape of dissolution media has been dynamically evolving with newer drugs entering the market among which most of them are either BCS class II or BCS class IV drugs exhibiting poor solubility.
Mehta, Tejal +2 more
core +1 more source
A water‐soluble and ‐stable 2,5‐bis(arylethynyl)rhodacyclopentadiene fluoresces, with no observable phosphorescence. However, competitive ISC to T1 leads to potent 1O2 sensitization. It binds strongly to DNA, RNA, and protein (BSA); efficiently enters living human cells accumulating preferentially in mitochondrial membranes; and is nontoxic even at ...
Shishir Ghosh +14 more
wiley +1 more source
CMPF’s contribution to the call for evidence on the European Media Freedom Act (EMFA) [PDF]
The European Commission announced in 2021 its will to draft a European Media Freedom Act (EMFA); in January 2022, it opened a public consultation in this regard.
Centre for Media Pluralism and Media Freedom
core +1 more source
Drug absorption across viable porcine intestines was investigated using an Ussing chamber system. The apparent permeability coefficients, Papp,pig, were compared to the permeability coefficients determined in humans in vivo, Peff,human. Eleven drugs from
Yvonne E. Arnold +3 more
doaj +1 more source
Biphasic dissolution systems achieved good predictability for the in vivo performance of several formulations of poorly water-soluble drugs by characterizing dissolution, precipitation, re-dissolution, and absorption.
Alexander Denninger +3 more
doaj +1 more source

