Results 141 to 150 of about 373,234 (333)

Molecular genetical analysis of the nitrate gene cluster of Aspergillus nidulans

, 2015
Putative DNA clones harbouring the nitrate gene cluster of Aspergillus nidulans was used in a number of transformation experiments to positively identify the clones.
Greaves, Philip Andrew
core  

Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin

, 2020
From our in-house microbial genome database of secondary metabolite producers, we identified a candidate biosynthetic gene cluster for desertomycin from Streptomyces nobilis JCM4274.
Junko Hashimoto, Noriyuki Satoh, Takuya Hashimoto, Hashimoto, Takuya, Suenaga, Hikaru, Fujie, Manabu, Satoh, Noriyuki, Ikeda, Haruo, Hashimoto, Junko, Kazuo Shin-ya, Kozone, Ikuko, Manabu Fujie, Shin-ya, Kazuo, Ikuko Kozone, Haruo Ikeda, Hikaru Suenaga   +15 more
core   +1 more source

Annotation of the cristazarin biosynthetic gene cluster in Cladonia metacorallifera.

, 2023
Annotation of the cristazarin biosynthetic gene cluster in Cladonia metacorallifera.
Jae-Seoun Hur (503549), Jung A. Kim (6669038), Wonyong Kim (331039), Jaycee Augusto Gumiran Paguirigan (16436565)   +3 more
core   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Correlation of Guaiacol Production With Presence and Expression of the Guaiacol Biosynthetic Gene Cluster in Alicyclobacillus Spp

eFood
The whole genome sequences of A. dauci DSM 28700, A. fastidiosus KKP 3000 (guaiacol producers), and A. fastidiosus DSM 17978 (non‐guaiacol producer) were firstly determined. Then, the presence of the guaiacol biosynthetic gene cluster in genome sequences
Rui Cai, Yanhui Li, Qi Wang, Hong Guo, Yuxiang Zhang, Yahong Yuan, Qinglin Sheng, Zhouli Wang, Tianli Yue   +8 more
doaj   +1 more source

Minimal lactazole scaffold for in vitro thiopeptide bioengineering

Nature Communications, 2020
Lactazole A is a thiopeptide from Streptomyces lactacystinaeus, encoded by a compact 9.8 kb biosynthetic gene cluster. Here, the authors show a platform for in vitro biosynthesis of lactazole A via a combination of a flexible in vitro translation system ...
Alexander A. Vinogradov, Morito Shimomura, Yuki Goto, Taro Ozaki, Shumpei Asamizu, Yoshinori Sugai, Hiroaki Suga, Hiroyasu Onaka   +7 more
doaj   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Overview of the turnerbactin biosynthetic gene cluster.

, 2013
A. Organization of genes involved in turnerbactin biosynthesis. The locations of putative Fur boxes are indicated by asterisks (*). The black triangle indicates the location of NRPS disruption. B. Domain organization of the NRPS modules of TnbF.
Brian Fishman (469711), Amaro E. Trindade-Silva (153934), Andrew W. Han (134007), Margo G. Haygood (134018), Carlos A. G. Soares (262422), Daniel L. Distel (134016), Alison Butler (469712), Moriah Sandy (469710)   +7 more
core   +1 more source

Identification and heterologous expression of the kocurin biosynthetic gene cluster

Microbiology, 2017
The antibiotically bioactive thiopeptide compound kocurin was identified in extracts from a newly isolated Kocuria rosea strain. The axenic strain was retrieved from a soil sample of the intertidal area at the Paracas National Park, Peru. The genetic basis of this promising natural product with activity against methicillin-resistant Staphylococcus ...
Luis, Linares-Otoya, Virginia, Linares-Otoya, Lizbeth, Armas-Mantilla, Cyntia, Blanco-Olano, Max, Crüsemann, Mayar L, Ganoza-Yupanqui, Julio, Campos-Florian, Gabriele M, König, Till F, Schäberle   +8 more
openaire   +2 more sources

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source