Results 41 to 50 of about 99,198 (289)
Heterologous expression of the diazaquinomycin biosynthetic gene cluster [PDF]
Journal of Industrial Microbiology and Biotechnology, 2019 Abstract Members of the diazaquinomycin class of natural products have shown potent and selective activity against Mycobacterium tuberculosis. However, poor aqueous solubility has prevented extensive studies in animal models thus far. Our long-term goal is to harness knowledge regarding diazaquinomycin biosynthesis towards the generation
Jana, Braesel +2 more
openaire +2 more sources
Permanent Draft Genome Sequences of Three Frankia sp. Strains That Are Atypical, Noninfective, Ineffective Isolates [PDF]
, 2017 Here, we present draft genome sequences for three atypical Frankia strains (lineage 4) that were isolated from root nodules but are unable to reinfect actinorhizal plants. The genome sizes of Frankia sp. strains EUN1h, BMG5.36, and NRRL B16386 were 9.91,
Ghodhbane-Gtari, Faten +11 more
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Digging for biosynthetic dark matter. [PDF]
, 2015 An analysis of bacterial communities in soil samples from around the world reveals unexplored diversity in biosynthetic ...
Moore, Bradley S, Zhang, Jia Jia
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Marine Drugs, 2015 The incorporation pattern of biosynthetic precursors into two structurally unique polyketides, akaeolide and lorneic acid A, was elucidated by feeding experiments with 13C-labeled precursors.
Tao Zhou +5 more
doaj +1 more source
Journal of Fungi, 2023 Genomic analysis has demonstrated that many fungi possess essential gene clusters for the production of previously unobserved secondary metabolites; however, these genes are normally reduced or silenced under most conditions.
Mengyao Xue +8 more
doaj +1 more source
Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetes [PDF]
, 2016 We are indebted with Marnix Medema, Paul Straight and Sean Rovito, for useful discussions and critical reading of the manuscript, as well as with Alicia Chagolla and Yolanda Rodriguez of the MS Service of Unidad Irapuato, Cinvestav, and Araceli Fernandez
Barona-Gomez, Francisco +7 more
core +1 more source
mSphere of Influence: Systematically Decoding Microbial Chemical Communication
mSphere, 2019 Laura A. Mike works in the field of bacterial pathogenesis. In this mSphere of Influence article, she reflects on how “Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters” by P. Cimermancic et al. (Cell 158:
Laura A. Mike
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Biosynthesis of thiocarboxylic acid-containing natural products. [PDF]
, 2018 Thiocarboxylic acid-containing natural products are rare and their biosynthesis and biological significance remain unknown. Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products ...
Deng, Youchao +9 more
core +1 more source
BMC Genomics, 2023 Exploring Brevibacterium strains from various ecosystems may lead to the discovery of new antibiotic-producing strains. Brevibacterium sp. H-BE7, a strain isolated from marine sediments from Northern Patagonia, Chile, had its genome sequenced to study ...
Andrés Cumsille +8 more
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Microbial Biotechnology, 2021 Summary Butenyl‐spinosyn, a promising biopesticide produced by Saccharopolyspora pogona, exhibits stronger insecticidal activity and a broader pesticidal spectrum. However, its titre in the wild‐type S.
Jie Rang +14 more
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