Butirosin-biosynthetic Gene Cluster from Bacillus circulans.
The Journal of Antibiotics, 2000 Butirosin is an interesting 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotic produced by non-actinomycete Bacilli. Recently we were successful in purification of 2-deoxy-scyllo-inosose synthase from butirosin-producer Bacillus circulans as the key enzyme for the biosynthesis of DOS, in cloning of the responsible gene (btrC), and in its ...
Yasumasa Ota +6 more
openaire +3 more sources
Identification and analysis of the paulomycin biosynthetic gene cluster and titer improvement of the paulomycins in Streptomyces paulus NRRL 8115. [PDF]
PLoS ONE, 2015 The paulomycins are a group of glycosylated compounds featuring a unique paulic acid moiety. To locate their biosynthetic gene clusters, the genomes of two paulomycin producers, Streptomyces paulus NRRL 8115 and Streptomyces sp. YN86, were sequenced. The
Jine Li +4 more
doaj +1 more source
An interpreted atlas of biosynthetic gene clusters from 1,000 fungal genomes
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Fungi represent an underexploited resource for new compounds with applications in the pharmaceutical and agriscience industries. Despite the availability of >1,000 fungal genomes, our knowledge of the biosynthetic space encoded by these ...
Matthew T. Robey +4 more
semanticscholar +1 more source
The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus [PDF]
Microbiology, 2006 The biosynthetic gene cluster for the 17 aa peptide antibiotic enduracidin has been cloned and sequenced from Streptomyces fungicidicus ATCC 21013. The 84 kb gene cluster contains 25 ORFs and is located within a 116 kb genetic locus that was fully sequenced.
Xihou, Yin, T Mark, Zabriskie
openaire +2 more sources
Genome Sequences of Serratia Strains Revealed Common Genes in Both Serratomolides Gene Clusters
Biology, 2020 Serratia strains are ubiquitous microorganisms with the ability to produce serratomolides, such as serrawettins. These extracellular lipopeptides are described as biocides against many bacteria and fungi and may have a nematicidal activity against ...
Catarina Marques-Pereira +2 more
doaj +1 more source
BioCAT: Search for biosynthetic gene clusters producing nonribosomal peptides with known structure
Computational and Structural Biotechnology Journal, 2022 Nonribosomal peptides are a class of secondary metabolites synthesized by multimodular enzymes named nonribosomal peptide synthetases and mainly produced by bacteria and fungi.
Dmitry N. Konanov +3 more
doaj +1 more source
Digging for biosynthetic dark matter. [PDF]
, 2015 An analysis of bacterial communities in soil samples from around the world reveals unexplored diversity in biosynthetic ...
Moore, Bradley S, Zhang, Jia Jia
core +2 more sources
Biosynthetic gene clusters and the evolution of fungal chemodiversity.
Natural product reports (Print), 2020 Covering: up to 2019Fungi produce a remarkable diversity of secondary metabolites: small, bioactive molecules not required for growth but which are essential to their ecological interactions with other organisms.
A. Rokas +4 more
semanticscholar +1 more source
Transcriptional regulation of the novobiocin biosynthetic gene cluster [PDF]
Microbiology, 2009 The aminocoumarin antibiotic novobiocin is a gyrase inhibitor formed by a Streptomyces strain. The biosynthetic gene cluster of novobiocin spans 23.4 kb and contains 20 coding sequences, among them the two regulatory genes novE and novG. We investigated the location of transcriptional promoters within this cluster by insertion of transcriptional ...
Dangel, Volker +6 more
openaire +3 more sources
Permanent Draft Genome Sequences of Three Frankia sp. Strains That Are Atypical, Noninfective, Ineffective Isolates [PDF]
, 2017 Here, we present draft genome sequences for three atypical Frankia strains (lineage 4) that were isolated from root nodules but are unable to reinfect actinorhizal plants. The genome sizes of Frankia sp. strains EUN1h, BMG5.36, and NRRL B16386 were 9.91,
Ghodhbane-Gtari, Faten +11 more
core +2 more sources