Results 121 to 130 of about 1,441,063 (301)

A review of glycosylation diversity and biosynthetic advances of steroidal saponins in Paris polyphylla var. yunnanensis

Frontiers in Plant Science
Steroidal saponins are the principal bioactive constituents of Paris polyphylla var. yunnanensis (P. polyphylla) and are widely used in traditional medicine and the pharmaceutical industry.
Yueyan Luo, Ran Guo, Xinyan He, Anzhong Peng, Longxing Li, Haifeng Li   +5 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in  Artemisia annua

Scientific Reports
Cold stress, a major abiotic factor, positively modulates the synthesis of artemisinin in Artemisia annua and influences the biosynthesis of other secondary metabolites.
Yunxiao He, Wenjing Zhang, Xianghua Zuo, Jiangnan Li, Ming Xing, Yujiao Zhang, Jian You, Wei Zhao, Xia Chen   +8 more
doaj   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

Advanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà, Giulia Cazzador, Roberta Fabbri, Matteo Calosi, Alessandro Silvestri, Andrea Candini, Fabiola Liscio, Franco Corticelli, Aikaterini Konstantoulaki, Andrea D'Iorio, Marco Caprini, Vincenzo Palermo, Monica Bertoldo, Valentina Benfenati, Chiara Zanardi, Emanuele Treossi   +15 more
wiley   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Evolutionary Spread of Distinct O‐methyltransferases Guides the Discovery of Unique Isoaspartate‐Containing Peptides, Pamtides

Advanced Science
Ribosomally synthesized and post‐translationally modified peptides (RiPPs) are a structurally diverse class of natural products with a distinct biosynthetic logic, the enzymatic modification of genetically encoded precursor peptides.
Hyunbin Lee, Sho Hee Park, Jiyoon Kim, Jaehak Lee, Min Sun Koh, Jung Ho Lee, Seokhee Kim   +6 more
doaj   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

In silico metabolic profiling of non-baumannii Acinetobacter species uncovers conserved functions and provides first evidence of siderophore biosynthetic genes in Acinetobacter junii

Scientific Reports
The genus Acinetobacter is recognized for its metabolic versatility, which contributes to environmental persistence, virulence, and antimicrobial resistance.
Samuel O. Ajoseh, Ahmed F. Hikal, Hanka Brangsch, Abdul-Azeez A. Anjorin, Mohamed I. A. Hassan, Gamal Wareth, Kabiru O. Akinyemi   +6 more
doaj   +1 more source

Aflatoxin Biosynthetic Pathway and Pathway Genes

, 2011
Among the over 185 known species within the genus Aspergillus, Aspergillus flavus is the most economically important because it produces the toxic and carcinogenic aflatoxins. Its non-aflatoxigenic relative A. oryzae is used extensively for food fermentations (Jelinek et al., 1989). It is one of the most abundant soil-borne molds on earth. A.
Jiujiang Yu, Kenneth C.
openaire   +2 more sources

Simplified hormone biosynthetic pathways.

, 2013
The hormone biosynthetic pathways of Arabidopsis for gibberellins A., ABA B., and, brassinolide C.. The biosynthesis mutants used in this study and sites of their lesions are shown.
Ferenc Nagy (22523), Elzbieta Sarnowska (359598), Seth J. Davis (359599), Malgorzata A. Domagalska (359597)   +3 more
core   +1 more source