Results 161 to 170 of about 1,441,063 (301)

tRNA-deacylase-directed discovery of biosynthetic pathways. [PDF]

Nat Chem
Millar DC, Zhou Y, Marchand JA, Roberts-Mataric H, Chen T, Hu CX, Fang J, Millar S, Stone EA, Pelton JG, Sosa MB, Chang MCY.   +11 more
europepmc   +1 more source

Molecular plant cell bioprocessing: Manipulation and characterisation of post-biosynthetic pathway towards hyperproduction of secondary metabolites

, 2008
Plant cell-based bioprocessing—is to use the biosynthetic pathways of plant cells/tissues for the production of useful metabolites (large and small molecules) and biotransformation.
张卫
core  

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

Advanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu, Yuwei Hu, Xukun Lu, Yuling Cai, Tongtong Li, Ming Gao, Jinlong Ma, Yuan Gao, Shangming Liu, Zi‐Jiang Chen, Jing Meng, Hongbin Liu, Xiaohua Jiang   +12 more
wiley   +1 more source

Bacterial-Derived Signals Selectively Remodel Glycosaminoglycan Biosynthetic Pathways in Reconstructed Human Corneal Epithelium. [PDF]

Int J Mol Sci
Blanco-Agudín N, Vázquez N, Ye S, Sánchez-Fernández C, Fernández-Vega I, Meana Á, Merayo-Lloves J, Quirós LM.   +7 more
europepmc   +1 more source

Photosynthesis and biosynthetic pathways to chemicals [PDF]

, 1980
openaire   +2 more sources

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

Advanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian, Shihang Pu, Zhipeng Xu, Yiheng Ding, Ling Jin, Baochao Li, Qi Li, Xiaohai Xi, Zengjun Wang, Jiajun Xing, Aiming Xu   +10 more
wiley   +1 more source

Squalene in <i>Camellia oleifera</i>: Biosynthetic Pathways, Regulatory Networks, and Functional Perspectives. [PDF]

Plants (Basel)
Wang A, Wang J, Deng S, Chen B, Zhang J, Ma L.   +5 more
europepmc   +1 more source

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

Protein Structure, Evolution and Regulation of CER3, a Core Enzyme Partitioning Carbon into Two Specific Wax Biosynthetic Pathways. [PDF]

Biology (Basel)
Niu Q, Liu L, Liu C, Lü S, Zhang H.
europepmc   +1 more source