Results 11 to 20 of about 1,377,424 (162)
Batch Culture Formulation of Live Biotherapeutic Products
Advanced Therapeutics, 2020 Live biotherapeutic products (LBPs) are an emerging therapeutic modality that have been clinically investigated for treating pathogenic infections and inflammatory diseases.
Kunyu Qiu, A. Anselmo
semanticscholar +4 more sources
The cost of convenience: Evaluating economic differences in SQ and IV biotherapeutic formulations.
Journal of Clinical Oncologye23163 Background: Subcutaneous (SQ) formulations of anti-neoplastic biotherapeutics provide an alternative to intravenous (IV) administration, offering shorter administration times and ...
Puneeth Indurlal +4 more
semanticscholar +2 more sources
Hydrogen/deuterium exchange-mass spectrometry analysis of high concentration biotherapeutics: application to phase-separated antibody formulations [PDF]
mAbs, 2019 High concentration biotherapeutic formulations are often required to deliver large doses of drugs to achieve a desired degree of efficacy and less frequent dose.
Yuwei Tian +3 more
semanticscholar +3 more sources
Pharmaceutics, 2022 Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been the most widely used excipients for the stabilization of protein therapeutics for years.
Angel J. Castañeda Ruiz +6 more
doaj +1 more source
Oxidation of polysorbates – An underestimated degradation pathway?
International Journal of Pharmaceutics: X, 2023 To ensure the stability of biologicals over their entire shelf-life, non-ionic surface-active compounds (surfactants) are added to protect biologics from denaturation and particle formation.
Johanna Weber +4 more
doaj +1 more source
Pharmaceutics, 2022 Faecalibacterium duncaniae is an intestinal commensal bacterium proposed as a next-generation probiotic due to its promising outcomes in the treatment and prevention of several human diseases, which demonstrate its multiple contributions to the host’s ...
Daniela Machado +6 more
doaj +1 more source
Formulation and delivery solutions for the next generation biotherapeutics
Journal of Controlled Release, 2021 In 2018 I was appointed full professor of Pharmaceutical Biotechnology & Delivery at the Pharmaceutics division of the department of Pharmaceutical Sciences at Utrecht University, The Netherlands. In this contribution to the Orations - New Horizons of the Journal of Controlled Release I will introduce my research group (see also www.uu.nl/pharmaceutics)
openaire +5 more sources
Indian Journal of Pharmaceutical Education and Research, 2023 This review gives an insight on the anticariogenic role of each of the individual strains of Lactobacillus probiotics on Streptococcus mutans bacterium associated with dental caries and also attempts to emphasize the commercially approved oral probiotic ...
V. Vedam +3 more
semanticscholar +1 more source
Optimizing Excipient Properties to Prevent Aggregation in Biopharmaceutical Formulations
Journal of Chemical Information and Modeling, 2023 Excipients are included within protein biotherapeutic solution formulations to improve colloidal and conformational stability but are generally not designed for the specific purpose of preventing aggregation and improving cryoprotection in solution.
T. King +4 more
semanticscholar +1 more source