Adipose derived mesenchymal stem cell secretome formulation as a biotherapeutic to inhibit growth of drug resistant triple negative breast cancer [PDF]
Scientific Reports, 2021 Abstract In the present study, a protocol was developed for processing of human adipose derived mesenchymal stem cell secretome formulation of varying concentration. Its molecular composition was evaluated, and its effectiveness in vitro using breast cancer cell lines, and in vivo in a nude mice breast cancer ...
Ragima Nadesh +7 more
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Microbial Biotechnology, 2023 Respiratory viruses such as influenza viruses, respiratory syncytial virus (RSV), and coronaviruses initiate infection at the mucosal surfaces of the upper respiratory tract (URT), where the resident respiratory microbiome has an important gatekeeper ...
Irina Spacova +15 more
doaj +1 more source
Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa. A proof-of-concept study [PDF]
, 2018 AIM To investigate the adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG (LGG) in the colonic mucosa of healthy and ulcerative colitis (UC) patients, both in vivo and ex vivo in an organ culture model.
Corleto, Vito Domenico +6 more
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Оценка некоторых показателей биохимического анализа крови больных раком молочной железы при применении таксанов [PDF]
, 2016 Изучены некоторые показатели биохимического анализа периферической крови у женщин на ранних стадиях рака молочной железы при приеме таксанов (паклитаксела, доцетаксела и абраксана).
Кривчикова, Ю. М.
core +3 more sources
Formulation and characterization of vaginal capsules and tablets providing fast release of live Lactobacillus spp. [PDF]
Arhiv za farmacijuLive biotherapeutic products (LBPs) are gaining significant medical importance as a new approach in the prevention and treatment of various conditions in the female population.
Aleksovski Aleksandar +5 more
doaj +1 more source
The role of the gut microbiome in colonization resistance and recurrent infection
Therapeutic Advances in Gastroenterology, 2022 The species composition of the human gut microbiota is related to overall health, and a healthy gut microbiome is crucial in maintaining colonization resistance against pathogens.
Anna Maria Seekatz +2 more
doaj +1 more source
Snake fang-inspired stamping patch for transdermal delivery of liquid formulations [PDF]
, 2019 A flexible microneedle patch that can transdermally deliver liquid-phase therapeutics would enable direct use of existing, approved drugs and vaccines, which are mostly in liquid form, without the need for additional drug solidification, efficacy ...
Ahn, Yujin +16 more
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Delivering natural products and biotherapeutics to improve drug efficacy [PDF]
, 2017 Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery ...
Al Qaraghuli, Mohammed M. +5 more
core +1 more source
Journal of Pharmaceutical Sciences, 2021 Formulation of protein-based therapeutics employ advanced formulation and analytical technologies for screening various parameters such as buffer, pH, and excipients. At a molecular level, physico-chemical properties of a protein formulation depend on self-interaction between protein molecules, protein-solvent and protein-excipient interactions.
Sandeep, Somani +7 more
openaire +3 more sources
siRNA Delivery to the Glomerular Mesangium Using Polycationic Cyclodextrin Nanoparticles Containing siRNA [PDF]
, 2015 There is an urgent need for new therapies that can halt or reverse the course of chronic kidney disease with minimal side-effect burden on the patient. Small interfering RNA (siRNA) nanoparticles are new therapeutic entities in clinical development that ...
Davis, Mark E. +4 more
core +3 more sources