Results 1 to 10 of about 452,561 (294)

Biotin methyl ester enhances cargo release in RUSH system and enables rapid biotinylation with TurboID [PDF]

Communications Biology
Biotin-streptavidin technology is a key tool in biotechnology. The engineering of streptavidin or streptavidin-like molecules and organic synthesis of biotin derivatives offer a variety of applications to meet the needs of researchers.
Taisei Uehara, Arata Takiguchi, Takuro Tojima, Akihiko Nakano, Shion Kagawa, Tatsuo Nehira, Takunori Satoh, Akiko K. Satoh   +7 more
doaj   +2 more sources

Biotin [PDF]

BioFactors, 2009
AbstractBiotin is a water‐soluble vitamin and serves as a coenzyme for five carboxylases in humans. Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation. This review describes mammalian biotin metabolism, biotin analysis, markers of biotin status, and biological ...
Janos, Zempleni, Subhashinee S K, Wijeratne, Yousef I, Hassan   +2 more
openaire   +4 more sources

The growth responses and antioxidant capabilities of melinjo (Gnetum gnemon L.) in different durations of drought stress

Annals of Agricultural Sciences, 2021
Melinjo (Gnetum gnemon L.) is a beneficial agroforestry plant that contains antioxidant compounds broadly studied as a natural source in pharmaceutical and nutraceutical uses.
Tri Agus Siswoyo, Laras Sekar Arum, Bella Rhea Lavifa Sanjaya, Zahela Siti Aisyah   +3 more
doaj   +1 more source

Chlorin e6-Biotin Conjugates for Tumor-Targeting Photodynamic Therapy

Molecules, 2021
To improve the tumor-targeting efficacy of photodynamic therapy, biotin was conjugated with chlorin e6 to develop a new tumor-targeting photosensitizer, Ce6-biotin. The Ce6-biotin had good water solubility and low aggregation.
Wei Liu, Xingqun Ma, Yingying Jin, Jie Zhang, Yang Li, Yuxia Tang, Yong Song, Shouju Wang   +7 more
doaj   +1 more source

Biotin conjugates in targeted drug delivery: is it mediated by a biotin transporter, a yet to be identified receptor, or (an)other unknown mechanism(s)?

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Conjugation of drugs with biotin is a widely studied strategy for targeted drug delivery. The structure–activity relationship (SAR) studies through H3-biotin competition experiments conclude with the presence of a free carboxylic acid being essential for
Ravi Tripathi, Anchala Guglani, Rujuta Ghorpade, Binghe Wang   +3 more
doaj   +1 more source

Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis. [PDF]

PLoS ONE, 2008
BACKGROUND: Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis.
Sudha Purushothaman, Garima Gupta, Richa Srivastava, Vasanthakumar Ganga Ramu, Avadhesha Surolia   +4 more
doaj   +1 more source

Biotinylated Quinone as a Chemiluminescence Sensor for Biotin-Avidin Interaction and Biotin Detection Application

Sensors, 2023
Biotin, or vitamin B7, is essential for metabolic reactions. It must be obtained from external sources such as food and biotin/vitamin supplements because it is not biosynthesized by mammals.
Fatema Kaladari, Mahmoud El-Maghrabey, Megumi Kawazato, Naoya Kishikawa, Naotaka Kuroda   +4 more
doaj   +1 more source

Competitive impedimetric aptasensors for detection of small molecule pollutants by the signal amplification of self-assembled biotin-phenylalanine nanoparticle networks

Electrochemistry Communications, 2020
Impedimetric aptasensors without signal amplification exhibit poor sensitivity for the detection of small molecule contaminants. In this work, biotinylated nanoparticles of biotin-FNPs were readily prepared by the self-assembly of biotin-phenylalanine ...
Ming La, Daohong Wu, Yanping Gao, Ning Xia, Yifan Niu, Lin Liu, Xinyao Yi   +6 more
doaj   +1 more source

Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum

BMC Microbiology, 2012
Background The amino acid-producing Gram-positive Corynebacterium glutamicum is auxotrophic for biotin although biotin ring assembly starting from the precursor pimeloyl-CoA is still functional.
Schneider Jens, Peters-Wendisch Petra, Stansen K Corinna, Götker Susanne, Maximow Stanislav, Krämer Reinhard, Wendisch Volker F   +6 more
doaj   +1 more source

Effect of supplementation of biotin in total mixed ration of dairy cows on rumen fermentation characteristics by in vitro gas production technique [PDF]

Journal of Veterinary and Animal Sciences, 2022
An experiment was conducted to assess the effect of supplementation of biotin on rumen fermentation parameters and microbial biomass production by in vitro gas production technique. Biotin was supplemented to the substrate - total mixed ration (TMR) at
K. Jasmine Rani, V. Dildeep, K. Ally, K. M. Syam Mohan, T. V. Aravindakshan, K. S. Anil   +5 more
doaj   +1 more source