Results 1 to 10 of about 149 (143)
BioFactors, 2009 AbstractBiotin is a water‐soluble vitamin and serves as a coenzyme for five carboxylases in humans. Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation. This review describes mammalian biotin metabolism, biotin analysis, markers of biotin status, and biological ...
Janos, Zempleni +2 more
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Biotin dependency due to a defect in biotin transport [PDF]
Journal of Clinical Investigation, 2002 We describe a 3-year-old boy with biotin dependency not caused by biotinidase, holocarboxylase synthetase, or nutritional biotin deficiency. We sought to define the mechanism of his biotin dependency. The child became acutely encephalopathic at age 18 months. Urinary organic acids indicated deficiency of several biotin-dependent carboxylases.
Stephen D. Cederbaum +10 more
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Studies on the biosynthesis of biotin. Production of biotin and biotin-like compounds by a pseudomonad [PDF]
Biochemical Journal, 1965 1. Filtrates from cultures of a strain of Pseudomonas aeruginosa, grown in a basal glucose-ammonium chloride-vitamins-salts medium, possessed biotin activity as detected by microbiological assays. Exponential-phase culture filtrates contained biotin and desthiobiotin in the approximate ratio 1:3, with smaller amounts of biotin sulphoxide and three ...
Mahboob Ilahi +2 more
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Relationship of Biotin Deposition in Turkey Eggs to Dietary Biotin and Biotin-Binding Proteins [PDF]
Poultry Science, 1987 The biotin and biotin-binding protein contents of egg yolk, egg albumen, and hen plasma were determined on eight groups of four turkey hens each that had been fed diets ranging from less than 10 to 3,475 micrograms available biotin per kilogram. Biotin deposition in the yolk was strongly dependent upon available dietary biotin below 100 micrograms/kg ...
Harold B. White +2 more
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Biological Precursors of Biotin and/or Biotin L-Sulfoxide
Experimental Biology and Medicine, 1955 SummaryPimelic and azelaic acids were found to be precursors of biotin L-sulfoxide in the growth of Aspergillus niger. Shorter chain dicarboxylic acids as well as suberic and se-bacic acids are inactive. A number of other miscellaneous compounds including oleic acid, Tween 80, and certain “traumatic acids, v with structural or functional relationships ...
Lemuel D. Wright +2 more
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Grow Biotin | Grow Biotin Hair | Grow Biotin Nails
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Chemistry & Biology, 2005 Biotin synthase catalyzes formation of a thiophane ring through a radical mechanism that is difficult to reconstitute in vitro. Choi-Rhee and Cronan measure a turnover of 20-60 equivalents of biotin in vivo, but also find that turnover renders the protein susceptible to proteolytic destruction.
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Biotin-vitamers Produced by a Biotin-requiring Mutant
Agricultural and Biological Chemistry, 1977 Biotin requirements for the growth of a mutant (KY–21–1–25–43–101) of a biotin-producing bacterium (Bacillus sp. KY–21–1–25) was examined and the characteristics of the biotinvitamers produced by the mutant was also examined. Either biotin or dethiobiotin supported the growth of the mutant, but pimelic acid, 7-keto-8-aminopeIargonic acid and 7, 8 ...
Mariko Shin +3 more
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Journal of Bacteriology, 1963 Eisenberg , M. A. (Columbia University, New York, N.Y.). Biotin biosynthesis. I. Biotin yields and biotin vitamers in cultures of Phycomyces blakesleeanus . J. Bacteriol. 86: 673–680. 1963.—The addition of pimelic acid to a well-aerated medium resulted in a 10- to 12-fold increase
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