Results 1 to 10 of about 277,237 (293)

Biotin interference in routine clinical immunoassays [PDF]

open access: yesPractical Laboratory Medicine
Background: Laboratory examinations play a crucial role in medical diagnostics and treatment, necessitating the identification of interference factors to ensure accurate results.
Kuo-Chun Chiu   +11 more
doaj   +2 more sources

Chlorin e6-Biotin Conjugates for Tumor-Targeting Photodynamic Therapy

open access: yesMolecules, 2021
To improve the tumor-targeting efficacy of photodynamic therapy, biotin was conjugated with chlorin e6 to develop a new tumor-targeting photosensitizer, Ce6-biotin. The Ce6-biotin had good water solubility and low aggregation.
Wei Liu   +7 more
doaj   +1 more source

Effect of supplementation of biotin in total mixed ration of dairy cows on rumen fermentation characteristics by in vitro gas production technique [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2022
An experiment was conducted to assess the effect of supplementation of biotin on rumen fermentation parameters and microbial biomass production by in vitro gas production technique. Biotin was supplemented to the substrate - total mixed ration (TMR) at
K. Jasmine Rani   +5 more
doaj   +1 more source

Biotin conjugates in targeted drug delivery: is it mediated by a biotin transporter, a yet to be identified receptor, or (an)other unknown mechanism(s)?

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Conjugation of drugs with biotin is a widely studied strategy for targeted drug delivery. The structure–activity relationship (SAR) studies through H3-biotin competition experiments conclude with the presence of a free carboxylic acid being essential for
Ravi Tripathi   +3 more
doaj   +1 more source

Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis. [PDF]

open access: yesPLoS ONE, 2008
BACKGROUND: Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis.
Sudha Purushothaman   +4 more
doaj   +1 more source

Self-Assembly System Based on Cyclodextrin for Targeted Delivery of Cannabidiol

open access: yesFrontiers in Chemistry, 2021
Cannabidiol (CBD) is one specific kind of the cannabinoid in Cannabis sativa L with a wide range of pharmacological activities. However, the poor water solubility and specificity of CBD limits its application in pharmaceutical field.
Panyong Zhu   +12 more
doaj   +1 more source

Production of mutant streptavidin protein and investigation of its effect on the performance of streptavidin [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): Streptavidin is a versatile protein in cell science. The tetramer structure of streptavidin plays a key role in this binding, but this form interferes with some assays.
Elham Didevara   +3 more
doaj   +1 more source

Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum

open access: yesBMC Microbiology, 2012
Background The amino acid-producing Gram-positive Corynebacterium glutamicum is auxotrophic for biotin although biotin ring assembly starting from the precursor pimeloyl-CoA is still functional.
Schneider Jens   +6 more
doaj   +1 more source

Mechanisms of biotin-regulated gene expression in microbes

open access: yesSynthetic and Systems Biotechnology, 2016
Biotin is an essential micronutrient that acts as a co-factor for biotin-dependent metabolic enzymes. In bacteria, the supply of biotin can be achieved by de novo synthesis or import from exogenous sources.
J. Satiaputra   +3 more
doaj   +1 more source

Water-mediated green synthesis of PbS quantum dot and its glutathione and biotin conjugates for non-invasive live cell imaging [PDF]

open access: yesRoyal Society Open Science, 2018
This study addresses the cellular uptake of nanomaterials in the field of bio-applications. In the present study, we have synthesized water-soluble lead sulfide quantum dot (PbS QD) with glutathione and 3-MPA (mercaptopropionic acid) as the stabilizing ...
M. Vijaya Bharathi   +4 more
doaj   +1 more source

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