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Biotin [PDF]

open access: yesBioFactors, 2009
AbstractBiotin is a water‐soluble vitamin and serves as a coenzyme for five carboxylases in humans. Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation. This review describes mammalian biotin metabolism, biotin analysis, markers of biotin status, and biological ...
Janos, Zempleni   +2 more
openaire   +4 more sources

Studies on the biosynthesis of biotin. Production of biotin and biotin-like compounds by a pseudomonad [PDF]

open access: greenBiochemical Journal, 1965
1. Filtrates from cultures of a strain of Pseudomonas aeruginosa, grown in a basal glucose-ammonium chloride-vitamins-salts medium, possessed biotin activity as detected by microbiological assays. Exponential-phase culture filtrates contained biotin and desthiobiotin in the approximate ratio 1:3, with smaller amounts of biotin sulphoxide and three ...
AH Rose   +2 more
openalex   +4 more sources

Effects of Biotin-Avidin Interactions on Hydrogel Swelling

open access: yesFrontiers in Chemistry, 2020
Affinity interactions between the small molecule biotin and the protein avidin have been used extensively to functionalize biomaterials. More recently, researchers have leveraged the changes in biotin-avidin affinity that occur upon biotin conjugation to
Talaial B. Alina   +3 more
doaj   +1 more source

The growth responses and antioxidant capabilities of melinjo (Gnetum gnemon L.) in different durations of drought stress

open access: yesAnnals of Agricultural Sciences, 2021
Melinjo (Gnetum gnemon L.) is a beneficial agroforestry plant that contains antioxidant compounds broadly studied as a natural source in pharmaceutical and nutraceutical uses.
Tri Agus Siswoyo   +3 more
doaj  

Biotin Auxotrophy and Biotin Enhanced Germ Tube Formation in Candida albicans

open access: yesMicroorganisms, 2016
Due to the increased number of immunocompromised patients, infections with the pathogen Candida albicans have significantly increased in recent years. C. albicans transition from yeast to germ tubes is one of the essential factors for virulence.
Nur Ahmad Hussin   +5 more
doaj   +1 more source

Biotin interference with laboratory test results [PDF]

open access: yesHospital Pharmacology
Introduction: Biotin interference in laboratory tests is a growing concern, particularly due to the widespread use of biotin not only as a therapeutic agent but also as a supplement in the cosmetic industry.
Strilić David Z.   +2 more
doaj   +1 more source

Biotin dependency due to a defect in biotin transport [PDF]

open access: yesJournal of Clinical Investigation, 2002
We describe a 3-year-old boy with biotin dependency not caused by biotinidase, holocarboxylase synthetase, or nutritional biotin deficiency. We sought to define the mechanism of his biotin dependency. The child became acutely encephalopathic at age 18 months. Urinary organic acids indicated deficiency of several biotin-dependent carboxylases.
Stephen D. Cederbaum   +10 more
openaire   +3 more sources

Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE

open access: yesChemistryOpen, 2020
The synthetic function‐spacer‐lipid (FSL) amphiphile biotin‐CMG‐DOPE is widely used for delicate ligation of living cells with biotin residues under physiological conditions.
Anton Zalygin   +14 more
doaj   +1 more source

Overexpression of biotin synthase and biotin ligase is required for efficient generation of sulfur-35 labeled biotin in E. coli

open access: yesBMC Biotechnology, 2010
Background Biotin is an essential enzyme cofactor that acts as a CO2 carrier in carboxylation and decarboxylation reactions. The E. coli genome encodes a biosynthetic pathway that produces biotin from pimeloyl-CoA in four enzymatic steps. The final step,
Prigge Sean T   +2 more
doaj   +1 more source

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