Results 41 to 50 of about 467,470 (351)

Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates

Molecules, 2023
Despite the strong anticancer activity of SN38 (7-ethyl-10-hydroxy-camptothecin), the severe side effects and loss of anticancer activity caused by the lack of selectivity to cancer cells and hydrolysis of ring E prevent its clinical application.
Yi Dai, Yang Zhang, Tianxiang Ye, Yue Chen   +3 more
doaj   +1 more source

SENSING IMMOBILIZED MOLECULES OF STREPTAVIDIN ON A SILICON SURFACE BY MALDI-TOF MASS SPECTROMETRY AND FLUORESCENCE MICROSCOPY [PDF]

, 2014
Indexación: Web of Science; Scielo.A hydrogen-terminated Si (111) surface was modified to form an aminoterminated monolayer for immobilization of streptavidin.
ARAYA, EYLEEN, ESCOBAR, CARLOS A., GUELL, ALEIX G., KOGAN, MARCELO J., SANZ, FAUSTO   +4 more
core   +2 more sources

Antioxidant responses of black glutinous rice to drought and salinity stresses at different growth stages

Open Agriculture
Black glutinous rice is a local pigmented rice that attracts the interest of many people due to its high nutritional value. While cultivating, black glutinous rice may experience abiotic stresses, such as drought and salinity threat. Drought and salinity
Rudiyanto Yosefine Fetik, Alfiana Okta Hadina, Putri Anandita Linggar, Rizkiantoro Ridho, Siswoyo Tri Agus   +4 more
doaj   +1 more source

Transungual Delivery, Anti-Inflammatory Activity, and In Vivo Assessment of a Cyclodextrin Polypseudorotaxanes Nail Lacquer

Pharmaceutics, 2020
A new cyclodextrin polypseudorotaxanes nail lacquer (Regenail®) containing biotin, methyl sulphonyl methane (MSM), and dimethylsilanediol salicylate was developed and evaluated in vitro and in vivo.
Francisco Fernández-Campos, Francesc Navarro, Adrian Corrales, Jordi Picas, Eloy Pena, Jordi González, Francisco J. Otero-Espinar   +6 more
doaj   +1 more source

Controlling ligand surface density on streptavidin-magnetic particles by a simple, rapid, and reliable chemiluminescent test [PDF]

, 2018
International ...
Bouzas Ramos, Diego, Costa Fernández, José Manuel, Gagey Eilstein, Nathalie, Pons, Kelly, Ruiz Encinar, Jorge, Trapiella Alfonso, Laura, Tsatsaris, Vassilis   +6 more
core   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Biotin interference in routine clinical immunoassays

Practical Laboratory Medicine
Background: Laboratory examinations play a crucial role in medical diagnostics and treatment, necessitating the identification of interference factors to ensure accurate results.
Kuo-Chun Chiu, Jia-Rong Jhan, Hsiao-Ni Yan, Yu-Chen Liao, Wen-Hui Lu, Kuan-Yi Lee, Li-Yuan Cheng, Chung-Kang Yeh, Ya-Fen Lee, Chiung-Hui Kuo, Kuei-Pin Chung, Tzu-I Chien   +11 more
doaj   +1 more source

Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles [PDF]

, 2008
Short interfering RNA (siRNA) attracts much attention for the treatment of various diseases. However, its delivery, especially via systemic routes, remains a challenge. Indeed, naked siRNAs are rapidly degraded, while complexed siRNAs massively aggregate
De Smedt, Stefaan, Demeester, Jo, Lentacker, Ine, Sanders, Niek, Vandenbroucke, Roosmarijn   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Silver Azide Nanoparticles Embedded into Silica as Energetic Nano-materials

Medžiagotyra, 2015
Silver azide is a primary high explosive that can be initiated by different means. In this work, silver azide nanoparticles were obtained, embedded into silica, and further derivatized with biotin.
Petre Ionita, Corneliu Ghica, Raluca Damian, Daniela Culita, Ioana Turcu   +4 more
doaj   +1 more source