Results 41 to 50 of about 488,335 (365)
Sensors, 2023 Biotin, or vitamin B7, is essential for metabolic reactions. It must be obtained from external sources such as food and biotin/vitamin supplements because it is not biosynthesized by mammals.
Fatema Kaladari +4 more
doaj +1 more source
Multiple barriers in forced rupture of protein complexes [PDF]
J. Chem. Phys. (2012) vol. 137, 055103, 2012 Curvatures in the most probable rupture force ($f^*$) versus log-loading rate ($\log{r_f}$) observed in dynamic force spectroscopy (DFS) on biomolecular complexes are interpreted using a one-dimensional free energy profile with multiple barriers or a single barrier with force-dependent transition state.
arxiv +1 more source
Multiple Sclerosis, 2016 Background: Treatment with MD1003 (high-dose biotin) showed promising results in progressive multiple sclerosis (MS) in a pilot open-label study. Objective: To confirm the efficacy and safety of MD1003 in progressive MS in a double-blind, placebo ...
A. Tourbah +16 more
semanticscholar +1 more source
Singular-phase nanooptics: towards label-free single molecule detection [PDF]
NATURE MATERIALS Volume: 12 Issue: 4 Pages: 304-309 Published: APR
2013, 2014 Non-trivial topology of phase is crucial for many important physics phenomena such as, for example, the Aharonov-Bohm effect 1 and the Berry phase 2. Light phase allows one to create "twisted" photons 3, 4 , vortex knots 5, dislocations 6 which has led to an emerging field of singular optics relying on abrupt phase changes 7.
arxiv +1 more source
ACS Omega, 2019 Overconsumption of biotin (5–100 mg daily) as a supplement by the general population poses a significant problem for clinical immunoassays (IAs) based on biotin–streptavidin (SA) interactions. This affinity pair has been exploited in immunoassays because
J. Luong, S. K. Vashist
semanticscholar +1 more source
Molecules, 2016 Avidin is a tetrameric protein that belongs to the calycin superfamily. It has been studied mainly because of its extraordinary affinity to biotin, which led to a wide range of applications based on the avidin-biotin system.
Paweł Strzelczyk +3 more
doaj +1 more source
Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE
ChemistryOpen, 2020 The synthetic function‐spacer‐lipid (FSL) amphiphile biotin‐CMG‐DOPE is widely used for delicate ligation of living cells with biotin residues under physiological conditions.
Anton Zalygin +14 more
doaj +1 more source
Hydrodynamics of quartz crystal microbalance experiments with liposome-DNA complexes [PDF]
Phys. Rev. Applied 13, 064059 (2020), 2020 The quartz crystal microbalance (QCM) is widely used to study surface adsorbed molecules, often of biological significance. However, the relation between raw acoustic response (frequency shift $\Delta f$ and dissipation factor $\Delta D$) and mechanical properties of the macromolecules still needs to be deciphered, particularly in the case of suspended
arxiv +1 more source
Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. [PDF]
, 2020 Background & aimsBiotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis.
Cahalan, Michael D +5 more
core
Electrophoretic behavior of streptavidin complexed to a biotinylated probe : A functional screening assay for biotin-binding proteins [PDF]
, 2005 The biotin-binding protein streptavidin exhibits a high stability against thermal denaturation, especially when complexed to biotin. Herein we show that, in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), streptavidin is stabilized ...
Humbert, Nicolas +2 more
core +1 more source