Results 51 to 60 of about 277,237 (293)

Biotin-Decorated PAMAM G4.5 Dendrimer Nanoparticles to Enhance the Delivery, Anti-Proliferative, and Apoptotic Effects of Chemotherapeutic Drug in Cancer Cells

open access: yesPharmaceutics, 2020
Biotin receptors are overexpressed by various types of solid cancer cells and play a significant role in tumor metabolism, growth, and metastasis. Thus, targeting the biotin receptors on tumor cells may enhance the efficiency and reduce the side-effects ...
Endiries Yibru Hanurry   +9 more
doaj   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Silver Azide Nanoparticles Embedded into Silica as Energetic Nano-materials

open access: yesMedžiagotyra, 2015
Silver azide is a primary high explosive that can be initiated by different means. In this work, silver azide nanoparticles were obtained, embedded into silica, and further derivatized with biotin.
Petre Ionita   +4 more
doaj   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

open access: yesAdvanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou   +5 more
wiley   +1 more source

Advances and prospects in microbial production of biotin

open access: yesMicrobial Cell Factories
Biotin, serving as a coenzyme in carboxylation reactions, is a vital nutrient crucial for the natural growth, development, and overall well-being of both humans and animals.
Donghan Ma   +4 more
doaj   +1 more source

Biotin and contribution to normal energy‐yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006

open access: yesEFSA Journal, 2015
Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

open access: yesMolecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen   +10 more
doaj   +1 more source

Biological Precursors of Biotin and/or Biotin L-Sulfoxide

open access: yesExperimental Biology and Medicine, 1955
SummaryPimelic and azelaic acids were found to be precursors of biotin L-sulfoxide in the growth of Aspergillus niger. Shorter chain dicarboxylic acids as well as suberic and se-bacic acids are inactive. A number of other miscellaneous compounds including oleic acid, Tween 80, and certain “traumatic acids, v with structural or functional relationships ...
Lemuel D. Wright   +2 more
openaire   +3 more sources

Wafer‐Scale Integration of α‐quartz Thin Films toward Super High Frequency Piezoelectric bioNEMS for Chikungunya Virus Detection

open access: yesAdvanced Functional Materials, EarlyView.
Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar   +12 more
wiley   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa   +5 more
wiley   +1 more source

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