FAIR and Effective Communication of Data on Chemical Contaminant Biotransformation in the Environment. [PDF]
Rich SL +9 more
europepmc +1 more source
Abstract The regio‐ and stereoselective hydroxylation of unactivated C(sp3)‐H bonds is an important reaction in organic synthesis. While bacterial alkane monooxygenase AlkB catalyzes the terminal hydroxylation of aliphatic esters with excellent regioselectivity, the molecular principles of substrate recognition and selectivity of this integral membrane
Jelena Spasic +8 more
wiley +1 more source
Engineering Pseudomonas taiwanensis VLB120 for regio- and stereospecific hydroxylation of L-lysine fueled by the Weimberg pathway. [PDF]
Nerke P, Handke J, Hubmann G, Lütz S.
europepmc +1 more source
Synthesis of Niraparib via Chemoenzymatic Dearomatization of Substituted Pyridines
The synthesis of the PARP inhibitor Niraparib has been achieved via a chemoenzymatic dearomatization strategy. Chemical reduction combined with a one‐pot enzymatic cascade comprising an amine oxidase (AmOx) and an ene imine reductase (EneIRED) allowed for asymmetric reduction with high enantioselectivity.
Tabea Gerlach +3 more
wiley +1 more source
Development of Metabolite-Responsive Transcription Factor Systems as Modular Platforms for Gene Expression Control. [PDF]
Ji H +5 more
europepmc +1 more source
Selenium biofortification: integrating one health and sustainability
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro +3 more
wiley +1 more source
Dynamic Enantioconvergent Desaturation of 4,5-Disubstituted γ-Lactones in Whole Cells of <i>Rhodococcus erythropolis</i>. [PDF]
Cancellieri MC +4 more
europepmc +1 more source
Integrated biosynthesis of the lignan (-)-pluviatolide in resting and growing <i>E. coli</i> cells. [PDF]
Knöfel R +5 more
europepmc +1 more source

