Results 211 to 220 of about 57,036 (277)

The Role of Dissolved Organic Carbon and Preadaptation in the Biotransformation of Trace Organic Chemicals during Aquifer Recharge and Recovery

, 2012
Mohamed Ouf
openalex   +2 more sources

Physiologically Based Pharmacokinetic Virtual Twin Approach for Fludarabine Dosing in Pediatric Hematopoietic Stem Cell Transplantation

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Fludarabine (Flu), administered as a prodrug Flu monophosphate, is a lymphodepleting agent used prior to hematopoietic stem cell transplantation (HSCT) which exhibits substantial pharmacokinetics (PK) variability, contributing to suboptimal outcomes.
Mourad Mseddi, Christa Nath, Khalil Ben Hassine, Vid Mlakar, Yvonne Gloor, Fanny Gonzales, Chakradhara Rao S. Uppugunduri, Youssef Daali, Steven Keogh, Marc Ansari   +9 more
wiley   +1 more source

On the Utilization and Characterization of External Biotransformation Systems in <i>In Vitro</i> Toxicology: A Critical Review of the Scientific Literature with Guidance Recommendations. [PDF]

ACS Environ Au
Lungu-Mitea S, Stein Åslund M, Reichstein I, Pinto-Vidal FA, Schiwy A, Hollert H, Jacobs MN, Hilscherová K.   +7 more
europepmc   +1 more source

Biotransformation of germacrane epoxides by Cichorium intybus

, 1995
Dennis P. Piet, Robert Schrijvers, Maurice C. R. Franssen, C.P.G.M. de Groot   +3 more
openalex   +2 more sources

Evaluation of Laboratory‐Scale Composting Reactors to Simulate Compost Barn Bedding Dynamics

Environmental Quality Management, Volume 35, Issue 3, Spring 2026.
ABSTRACT Efficient management of compost bedding is essential for sustainability and animal welfare in Compost Barns (CBs). This study evaluated laboratory‐scale bioreactors as tools to simulate CB composting dynamics, focusing on temperature control, aeration, and wood shaving supplementation. Three sequential experiments were conducted. Test 1 used a
Gabriela Maria Fernandes Fiães, Marcelo Henrique Otenio, Luana de Araújo Coimbra, Caio de Teves Inácio, Leonardo de Souza Ramos   +4 more
wiley   +1 more source

Metagenomic analysis of bile acid biotransformation by gut microbiota in wild birds. [PDF]

Poult Sci
Yang MT, Xie LH, Wang L, Gao YQ, Liu R, Ma H, Lei CC, Jiang J, Su JW, Zhang XX, Ni HB, Nan FL.   +11 more
europepmc   +1 more source

Impact of CYP2D6 Metabolizer Status on Ondansetron Efficacy in Early Pregnancy Induced Nausea and Vomiting: A Case Control Study

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Real‐world data investigating CYP2D6 on the efficacy of ondansetron for nausea and vomiting in pregnancy (NVP) is lacking. Evidence shows CYP2D6 ultrarapid metabolizers are at risk of ondansetron nonresponse due to increased metabolism. We conducted a retrospective cohort study of early pregnant patients on ondansetron for NVP.
Michelle Liu, Megan M. Shuey, Sabrina E. Holley, Darlene F. Fountain, James Jaworski, Carol Griffin, Jeewoo Kim, Melissa Stec, Sudeep D. Sunthankar, Henry H. Ong, Srushti Gangireddy, Wei‐Qi Wei, Andrea Gaedigk, Digna R. Velez Edwards, Vivian K. Kawai   +14 more
wiley   +1 more source

Zearalenone Biotransformation by Tibetan Plateau-Derived Yeast Hannaella zeae: Biological Pattern Elucidation, Metabolite Safety, and Environmental Tolerance. [PDF]

Toxins (Basel)
Yang C, Hu J, Jiang D, Ni G, Wu C, Chu Q, Eremin SA, Mukhametova LI, Guo X, De J, Liu X, Hu H.   +11 more
europepmc   +1 more source

The mercapturic acid biotransformation pathway of hexachlorobenzene is not involved in the induction of splenomegaly, or skin and lung lesions in the Brown Norway rat

, 2000
Carola P.P.C. Michielsen, Sjef Boeren, Ivonne M.C.M. Rietjens, F. van Mil, Joseph G. Vos, Nanne Bloksma   +5 more
openalex   +2 more sources

Comparison of Two Artificial Liver Treatments for Acute Liver Failure: A Retrospective Observational Study

Nursing in Critical Care, Volume 31, Issue 2, March 2026.
ABSTRACT Background Liver failure can lead to severe disorders in the body's metabolism, detoxification, synthesis and other functions, with a high mortality rate of 60%–90%. The dual plasma molecular adsorption system (DPMAS) is a new artificial liver technology that has received much attention in recent years.
Xiulian Wu, Dongxia Wu, Xiaoqing Sun, Wenhui Wang, Jiayuan Wei, Xin Liu, Yanmei Gu   +6 more
wiley   +1 more source