Results 1 to 10 of about 19,479 (186)

Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria

Metabolites, 2022
Metabolomic analyses in alkaptonuria (AKU) have recently revealed alternative pathways in phenylalanine-tyrosine (phe-tyr) metabolism from biotransformation of homogentisic acid (HGA), the active molecule in this disease.
Brendan P. Norman, Andrew S. Davison, Bryony Hickton, Gordon A. Ross, Anna M. Milan, Andrew T. Hughes, Peter J. M. Wilson, Hazel Sutherland, Juliette H. Hughes, Norman B. Roberts, George Bou-Gharios, James A. Gallagher, Lakshminarayan R. Ranganath   +12 more
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Biotransformation

Clinical Pharmacology & Therapeutics, 2014
The field of clinical pharmacology and therapeutics spans a wide spectrum of research areas involving human subjects at both individual and population levels. One of the key concepts relevant to all of these research areas is biotransformation of drug molecules, which can be defined as the chemical modification of drugs within an organism.
openaire   +3 more sources

Transformações biológicas: contribuições e perspectivas Biological transformations: contributions and perspectives

Química Nova, 2009
In a moment that amazingly advances are being reached on the development of technologies to obtain high value chemical compounds as polymers, fine chemicals, pharmaceutical industry intermediates and chemical entities, we cannot refuse that a meaningful ...
Luciana Gonzaga de Oliveira, Simone Moraes Mantovani   +1 more
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Crystal structure of 1-tosyl-1,2,3,4-tetrahydroquinoline

Acta Crystallographica Section E, 2014
In the title compound, C16H17NO2S, the heterocyclic ring adopts a half-chair conformation and the bond-angle sum at the N atom is 350.2°. The dihedral angle between the planes of the aromatic rings is 47.74 (10)°.
S. Jeyaseelan, K.V. Asha, G. Venkateshappa, P. Raghavendrakumar, B.S. Palakshamurthy   +4 more
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Dip Hopping Technique and Yeast Biotransformations in Craft Beer Productions

Fermentation, 2023
This paper evaluates the effects of an alternative hopping technique, called dip hopping, on beer. This technique involves infusing hops in hot water (or in a portion of wort) and subsequently combining the infusion with the wort (after wort cooling ...
Paolo Passaghe, Lara Tat, Alba Goi, Luca Vit, Stefano Buiatti   +4 more
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Glucosidase Inhibitors Screening in Microalgae and Cyanobacteria Isolated from the Amazon and Proteomic Analysis of Inhibitor Producing Synechococcus sp. GFB01

Microorganisms, 2021
Microalgae and cyanobacteria are good sources for prospecting metabolites of biotechnological interest, including glucosidase inhibitors. These inhibitors act on enzymes related to various biochemical processes; they are involved in metabolic diseases ...
Diana Gomes Gradíssimo, Vivian Cássia Oliveira da Silva, Luciana Pereira Xavier, Sidney Vasconcelos do Nascimento, Rafael Borges da Silva Valadares, Silvia Maria Mathes Faustino, Maria Paula Cruz Schneider, Agenor Valadares Santos   +7 more
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Physicochemical and Biological Properties of Menthol and Thymol-Based Natural Deep Eutectic Solvents

Molecules
Seven hydrophobic deep eutectic solvents (hDESs) were characterised to evaluate their potential applicability in different industries and their environmental impact.
Martina Bagović Kolić, Martina Železnjak, Ksenija Markov, Višnja Gaurina Srček, Marina Cvjetko Bubalo, Kristina Radošević, Ivana Radojčić Redovniković   +6 more
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Stemodane Diterpenes and Diterpenoids: Isolation, Structure Elucidation, Biogenesis, Biosynthesis, Biological Activity, Biotransformations, Metabolites and Derivatives Biological Activity, Rearrangements

Molecules, 2021
The scientific activity carried out over forty-five years on stemodane diterpenes and diterpenoids structure elucidation, biogenesis, biosynthesis, biological activity and biotransformations was reviewed.
Francesca Leonelli, Luisa Maria Migneco, Alessio Valletta, Rinaldo Marini Bettolo   +3 more
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Evolutionary Relationships Between the Laccase Genes of Polyporales: Orthology-Based Classification of Laccase Isozymes and Functional Insight From Trametes hirsuta

Frontiers in Microbiology, 2019
Laccase is one of the oldest known and intensively studied fungal enzymes capable of oxidizing recalcitrant lignin-resembling phenolic compounds. It is currently well established that fungal genomes almost always contain several non-allelic copies of ...
Olga S. Savinova, Konstantin V. Moiseenko, Ekaterina A. Vavilova, Andrey M. Chulkin, Tatiana V. Fedorova, Tatiana V. Tyazhelova, Daria V. Vasina   +6 more
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Biocatalysis and Flow Chemistry: Artificial Cell Factories

CHIMIA, 2020
Our research focusses on highly sustainable enzymatic methods for the preparation of valuable molecules, spanning from pharmaceuticals, to small chiral intermediates, to flavours and perfumes.
Francesca Paradisi
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