Results 31 to 40 of about 19,479 (186)

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen
22‐Hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) are useful precursors for the synthesis of steroidal active pharmaceutical ingredients.
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
doaj   +1 more source

Asymmetric synthesis of a high added value chiral amine using immobilized ω-transaminases

Beilstein Journal of Organic Chemistry, 2019
Chiral N-heterocyclic molecules and in particular compounds with an amino functional group such as 3-aminopiperidine are valuable intermediates for the production of a large number of bioactive compounds with pharmacological properties.
Antonella Petri, Valeria Colonna, Oreste Piccolo   +2 more
doaj   +1 more source

Lactones with Methylcyclohexane Systems Obtained by Chemical and Microbiological Methods and Their Antimicrobial Activity

Molecules, 2015
Eight new lactones (δ-chloro-, δ-bromo- and δ-iodo-γ-lactones), each with a methylcyclohexane ring, were obtained by chemical means from (4-methylcyclohex-2-en-1-yl) acetic acid or (6-methylcyclohex-2-en-1-yl) acetic acid.
Małgorzata Grabarczyk, Katarzyna Wińska, Wanda Mączka, Anna K. Żołnierczyk, Barbara Żarowska, Mirosław Anioł   +5 more
doaj   +1 more source

Glycosylation of Methoxylated Flavonoids in the Cultures of Isaria fumosorosea KCH J2

Molecules, 2018
Flavonoids are widely described plant secondary metabolites with high and diverse pro-health properties. In nature, they occur mostly in the form of glycosides.
Monika Dymarska, Tomasz Janeczko, Edyta Kostrzewa-Susłow   +2 more
doaj   +1 more source

Whole cells of recombinant CYP153A6-E. coli as biocatalyst for regioselective hydroxylation of monoterpenes

AMB Express, 2022
Keypoints Different monoterpenes can be regioselectively hydroxylated by CYP153A6 monooxygenase The biotransformation with whole cells is complementary to chemical oxyfunctionalization Fed-batch biotransformations have been applied for preparative ...
Pietro Cannazza, Marco Rabuffetti, Silvia Donzella, Valerio De Vitis, Martina L. Contente, Maria da Conceição Ferreira de Oliveira, Marcos C. de Mattos, Francisco G. Barbosa, Ricardo Pinheiro de Souza Oliveira, Andrea Pinto, Francesco Molinari, Diego Romano   +11 more
doaj   +1 more source

The Incubation of 13a,17-Dihydroxystemodane with Cephalosporium aphidicola

Molecules, 2012
The biotransformation of 13a,17-dihydroxystemodane (3) with the fungus Cephalosporium aphidicola afforded 13a,17,18-trihydroxystemodane (4), 3b,13a,17-tri-hydroxystemodane (5), 13a,17-dihydroxy-stemodan-18-oic acid (6), 3b,11β,13a,17-tetra ...
Juan A. Garbarino, María C. Chamy, Melchor G. Hernández, Ricardo Guillermo, Braulio M. Fraga   +4 more
doaj   +1 more source

Supercritical Carbon Dioxide and Its Potential as a Life-Sustaining Solvent in a Planetary Environment

Life, 2014
Supercritical fluids have different properties compared to regular fluids and could play a role as life-sustaining solvents on other worlds. Even on Earth, some bacterial species have been shown to be tolerant to supercritical fluids.
Nediljko Budisa, Dirk Schulze-Makuch
doaj   +1 more source

Optimization of Polyhydroxybutyrate Production by Amazonian Microalga Stigeoclonium sp. B23

Biomolecules, 2020
The present work established the optimization and production of biodegradable thermoplastic polyhydroxybutyrate (PHB) from Amazonian microalga Stigeoclonium sp. B23.
Murilo Moraes Mourão, Diana Gomes Gradíssimo, Agenor Valadares Santos, Maria Paula Cruz Schneider, Silvia Maria Mathes Faustino, Vitor Vasconcelos, Luciana Pereira Xavier   +6 more
doaj   +1 more source

Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria

Food Technology and Biotechnology, 2008
Whole cells of hydrocarbon-degrading bacteria, isolated from polluted sediments in the Santos Estuary (Baixada Santista, São Paulo, Brazil), were able to catalyse oxidoreduction reactions with various substituted phenylethanols and acetophenones as ...
Edna Kagohara, Vivian Helena Pellizari, João Valdir Comasseto, Leandro Helgueira Andrade, André Luiz Meleiro Porto   +4 more
doaj  

Enhancing stress-resistance for efficient microbial biotransformations by synthetic biology

Frontiers in Bioengineering and Biotechnology, 2014
Chemical conversions mediated by microorganisms, otherwise known as microbial biotransformations, are playing an increasingly important role within the biotechnology industry.
Haiyang eJia, Yanshuang eFan, Xudong eFeng, Chun eLi   +3 more
doaj   +1 more source