Results 231 to 240 of about 8,870 (277)

H–bonded mesogenic unsymmetric bis-heterocycles

Journal of Molecular Liquids, 2018
Abstract Five new series of bis−heterocycles containing isoxazole and pyrazole were reported, and their mesomorphic properties were investigated. A polar phenolic−OH group incorporated in compounds 1b–c and 1e is to probe the possible H−bonds induced.
Gou-Wei Luo, Chien-Yu Hu, Zih-Yang Lei, Gene-Hsiang Lee, Chung K. Lai   +4 more
openaire   +1 more source

Parallel Synthesis of Bis-heterocyclic Isoxazolylmethyl- and Isoxazolinylmethylpyrazoles

Journal of Combinatorial Chemistry, 2009
The solution-phase parallel synthesis of a 136-member library of isoxazol(in)e-CH(2)-pyrazoles is described. X-ray crystallographic structure determination verified the regioselectivities of the N-alkylation and nitrile oxide 1,3-dipolar cycloaddition steps.
Liping, Meng, Beth A, Lorsbach, Thomas C, Sparks, James C, Fettinger, Mark J, Kurth   +4 more
openaire   +2 more sources

Combinatorial Synthesis of Oxazol-Thiazole Bis-Heterocyclic Compounds

ACS Combinatorial Science, 2013
A combinatorial library of novel oxazol-thiazole bis-heterocycles was synthesized in good to excellent overall yields with high purity using a solution and solid-phase parallel synthesis approach. Oxazole amino acids, prepared from serine methyl ester and amino acids via coupling and cyclodehydration, were treated with Fmoc-NCS and α-haloketones for ...
Siva, Murru, Adel, Nefzi
openaire   +2 more sources

Machine learning applied to bi-heterocyclic drugs recognition

2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), 2017
The application of various statistical machine learning methods for the identification of bi-heterocyclic drugs that are based on the THz spectra is presented. A comparison of classification efficiency with six algorithms (LDA, QDA, SVM, Naive Bayes, KNN with Euclidean metrics and the cosine similarity) is shown and a complete THz system allowing for ...
Nowak, M.R., Nowak, K., Grzelczak, M., Szlachetko, B., Sterczewski, L., Pliński, E.F., Malinka, Wiesław   +6 more
openaire   +2 more sources

ChemInform Abstract: BIS HETEROCYCLES AS POSSIBLE FUNGICIDES

Chemischer Informationsdienst, 1984
AbstractAus den Dicarbonsäuredihydraziden (I) werden durch Cyclisierung mit Schwefelkohlenstoff die Bis‐(mercaptooxadiazolynalkane (II), durch Umsetzung mit Arylisothiocyanaten (III) die Thiosemicarbazide (IV) und durch deren Cyclisierung die Bis‐(mercaptotriazolyh‐ und Bis‐(arylaminothiadiazolyD‐alkane (V) und (VI) synthetisiert.
V. K. MISHRA, S. C. BAHEL
openaire   +1 more source

Synthesis of Some New Pyridine-2,6-bis-heterocycles

HETEROCYCLES, 2012
Disubstituted pyridines with functionalized azole and azine moieties are synthesized by reaction of the multifunctional, hitherto unknown pyridine derivative (III) with 1,2- or 1,3-binucleophiles including amino-substituted heterocycles.
Ahmad M. Farag, Mohamed A. Elsayed, Korany A. Ali   +2 more
openaire   +1 more source

Mesogenic bis-heterocycles incorporating both pyrazole and isoxazole

Tetrahedron, 2015
Abstract Two new series of mesogenic bis-heterocyclic derivatives containing pyrazoles and isoxazoles 1a–b were reported. One single crystallographic structure of mesogenic 2a (n=8) was determined by X-ray analysis, and it crystallizes in a triclinic space group P-1, with a=7.0511(2), b=7.6303(2) and c=21.2143(5) A, and Z=2.
Yu-Lun Li, Gene-Hsiang Lee, Chung K. Lai
openaire   +1 more source

Visualized fabric discoloration of bi-heterocyclic hydrazone dyes

Dyes and Pigments, 2017
Abstract A series of bi-heterocyclic hydrazone dyes have been synthesized by classic diazotization reactions between 2-amino-3-cyano-4-chloro-5-formylthiophene and five pyridine-2,6-dione based coupling components, including two acetal products undergoing dimethylacetalization of aldehyde group in the presence of methanol and glacial acetic acid.
Hui-Fen Qian, Xiao-Lei Zhao, Yuan Dai, Wei Huang   +3 more
openaire   +1 more source

Synthesis, antimicrobial and cytotoxic activities of sulfone linked bis heterocycles

European Journal of Medicinal Chemistry, 2012
A new class of sulfone linked bis heterocycles viz., pyrrolyl/pyrazolyl arylaminosulfonylmethyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles, and 1,2,4-triazoles were prepared and tested for antimicrobial activity and cytotoxicity. The chloro-substituted compounds 5c, 8c and 14c showed comparable antibacterial activity to chloramphenicol against ...
A, Muralikrishna, B C, Venkatesh, V, Padmavathi, A, Padmaja, P, Kondaiah, N Siva, Krishna   +5 more
openaire   +2 more sources

Synthesis of a New Class of Keto‐Linked Bis Heterocycles.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
V. Padmavathi, B. Jagan Mohan Reddy, B. Chandra Obula Reddy, A. Padmaja   +3 more
openaire   +1 more source