Results 81 to 90 of about 1,494 (196)

Cyclopropanation of Some Alkaloids [PDF]

, 2015
New derivatives of natural compounds, galanthamine using in treatment of  Alzheimer’s disease and antitumor dimer alkaloids vinblastine and vincristine were synthesized.
Hazai, László, Kalaus, György, Keglevich, Péter, Szántay, Csaba   +3 more
core   +2 more sources

Synthesis of Alkaloids and Compounds Containing the 3,4‐Benzomorphan Scaffold

European Journal of Organic Chemistry, Volume 27, Issue 1, January 2, 2024.
This review summarizes the biosynthesis and the synthesis of several biologically active natural compounds (i. e., alkaloids) and other related compounds containing the hexahydro‐2,6‐methano‐1‐benzazocine structure (i. e., 3,4‐benzomorphan scaffold). Abstract Several natural products, bearing an embedded hexahydro‐2,6‐methano‐1‐benzazocine framework (3,
Laura G. Rodríguez, Josep Bonjoch, Ben Bradshaw   +2 more
wiley   +1 more source

Globospiramine Exhibits Inhibitory and Fungicidal Effects against Candida albicans via Apoptotic Mechanisms

Biomolecules
Candidiasis is considered an emerging public health concern because of the occurrence of drug-resistant Candida strains and the lack of an available structurally diverse antifungal drug armamentarium.
Joe Anthony H. Manzano, Simone Brogi, Vincenzo Calderone, Allan Patrick G. Macabeo, Nicanor Austriaco   +4 more
doaj   +1 more source

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 1, January 2024.
Abstract Breast cancer is the most prevalent cancer worldwide and its incidence increases with age, posing a significant threat to women's health globally. Due to the clinical heterogeneity of breast cancer, the majority of patients develop drug resistance and metastasis following treatment.
Anqi Ge, Qi He, Da Zhao, Yuwei Li, Junpeng Chen, Ying Deng, Wang Xiang, Hongqiao Fan, Shiting Wu, Yan Li, Lifang Liu, Yue Wang   +11 more
wiley   +1 more source

Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of Cyphostemma adenocaule: A Combined In Vitro and In Silico Study

Journal of Tropical Medicine, Volume 2024, Issue 1, 2024.
Cyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant.
Hadush Gebrehiwot, Yadessa Melaku, Muhdin Aliye, Urgessa Ensermu, Aman Dekebo, Milkyas Endale, Daniel Rentsch, Mo Hunsen, Zhengwei Huang   +8 more
wiley   +1 more source

First De Novo Synthesis of the Bisindole Alkaloid Vinblastine.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +4 more sources

Circular dichroism studies of bisindole Vinca alkaloids

Tetrahedron, 1998
Abstract The analysis of a series of seventeen vinblastine analogs by circular dichroism is described. Exciton coupling of the indole and indoline chromophores of these compounds provides a general, non-empirical method for the assignment of the C16′ configuration with the bioactive C16′-S and the inactive C16′-R analogs giving rise, respectively, to
Craig A. Parish, Jian-Guo Dong, William G. Bornmann, Joan Chang, Koji Nakanishi, Nina Berova   +5 more
openaire   +1 more source

Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Indole Alkaloids Isolated from Catharanthus roseus (L.) G. Don Cultivated Conventionally and Derived from In vitro Cultures [PDF]

, 2016
Catharanthus roseus (periwinkle) is a medicinal plant commonly known for its wide biological activity. In many countries different parts of this plant are used for the treatment of diabetes, hypertension and for menstrual regulation.
GRZESZCZUK, Monika, KULPA, Danuta, WESOŁOWSKA, Aneta, WILAS, Janusz   +3 more
core   +2 more sources

Asymmetric Ion-Pairing Catalysis [PDF]

, 2014
Chemistry and Chemical ...
Brak, Katrien, Jacobsen, Eric N.
core   +1 more source

Rare Bisindole Alkaloids from the Amazonian Tree Raputia simulans

Chemistry & Biodiversity, 2014
AbstractThe stem bark of Raputia simulans (Rutaceae) has been reported to contain simple and dimeric indole alkaloids. Further phytochemical investigation of R. simulans stem bark resulted in the isolation of three new alkaloids. These compounds represent a relatively new category of dimeric indole alkaloids with a cyclohexene moiety in their core ...
Vougogiannopoulou, K., Travasarou, A., Fokialakis, N., Skaltsounis, A.L.   +3 more
openaire   +3 more sources