Results 51 to 60 of about 695 (146)

Circular dichroism studies of bisindole Vinca alkaloids

Tetrahedron, 1998
Abstract The analysis of a series of seventeen vinblastine analogs by circular dichroism is described. Exciton coupling of the indole and indoline chromophores of these compounds provides a general, non-empirical method for the assignment of the C16′ configuration with the bioactive C16′-S and the inactive C16′-R analogs giving rise, respectively, to
Craig A. Parish, Jian-Guo Dong, William G. Bornmann, Joan Chang, Koji Nakanishi, Nina Berova   +5 more
openaire   +1 more source

Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

European Journal of Histochemistry, 2018
Marine organisms such as corals, sponges and tunicates produce active molecules which could represent a valid starting point for new drug development processes. Among the various structural classes, the attention has been focused on 2,2-bis(6-bromo-3-indolyl) ethylamine, a marine alkaloid which showed a good anticancer activity against several tumor ...
S. Salucci, S. Burattini, F. Buontempo, E. Orsini, L. Furiassi, M. Mari, S. Lucarini, A. M. Martelli, E. Falcieri.   +8 more
openaire   +4 more sources

Synthesis of Topsentin‐A, A Bisindole Alkaloid of the Marine Sponge Topsentia genitrix

Bulletin des Sociétés Chimiques Belges, 1987
AbstractThe synthesis of topsentin‐A, a bisindole alkaloid isolated from the maring sponge Topsentia genitrix, has been achieved starting from 3‐acetylindole.
Braekman, Jean Claude, Daloze, Désiré, Stoller, Catherine   +2 more
openaire   +3 more sources

Cathagines A–D, new bisindole alkaloids from Catharanthus roseus

Journal of Natural Medicines
Four new bisindole alkaloids, cathagines A (1)-D (4) consisting of an aspidosperma and the fused tetracyclic 3-spirooxindole derived from an iboga type skeleton were isolated from the whole plant of Catharanthus roseus. The structures including absolute stereochemistry were elucidated on the basis of 2D NMR data and CD spectra.
Yusuke, Hirasawa, Chiaki, Kasagi, Erika, Koyama, Hitomi, Myojin, Takahiro, Tougan, Toshihiro, Horii, Nahoko, Uchiyama, Toshio, Kaneda, Hiroshi, Morita   +8 more
openaire   +2 more sources

Bisindole Alkaloids from a New Zealand Deep-Sea Marine Sponge Lamellomorpha strongylata. [PDF]

Mar Drugs, 2019
Ragini K, Piggott AM, Karuso P.
europepmc   +1 more source

Taburnaemines A-I, Cytotoxic Vobasinyl-Iboga-Type Bisindole Alkaloids from Tabernaemontana corymbosa. [PDF]

J Nat Prod, 2018
Zhang Y, Yuan YX, Goto M, Guo LL, Li XN, Morris-Natschke SL, Lee KH, Hao XJ.   +7 more
europepmc   +1 more source

Tabercorymines A and B, Two Vobasinyl-Ibogan-Type Bisindole Alkaloids from Tabernaemontana corymbosa. [PDF]

Org Lett, 2017
Yuan YX, Zhang Y, Guo LL, Wang YH, Goto M, Morris-Natschke SL, Lee KH, Hao XJ.   +7 more
europepmc   +1 more source

Stereochemical Analysis of Natural Products: Bisindole Alkaloids of the <i>Strychnos-Strychnos</i> Type. [PDF]

Int J Mol Sci
Grigoriev DA, Semenov VA, Angenot L, Krivdin LB.   +3 more
europepmc   +1 more source

Total Synthesis of Strempeliopidine and Non-Natural Stereoisomers through a Convergent Petasis Borono-Mannich Reaction. [PDF]

J Am Chem Soc, 2023
Rand AW, Gonzalez KJ, Reimann CE, Virgil SC, Stoltz BM.   +4 more
europepmc   +1 more source

K⁺/Cu²⁺ Co-chelated diastereoselective Friedel-Crafts reaction with chiral <i>N</i>-sulfinyl ketimines for the facile synthesis of chiral bisindoles and their cytotoxicity. [PDF]

RSC Adv
Yan S, Xu M, Liu Y, Du Z, Zhang G, Liu Z, Xiao J, Guo X, Liao G, Min Q, Xie B, Qin S.   +11 more
europepmc   +1 more source