Results 51 to 60 of about 70,439 (171)

Mechanochemistry in Organic Synthesis: An Italian Journey through Innovations

European Journal of Organic Chemistry, Volume 27, Issue 30, August 12, 2024.
The contribution of Italy to the development of mechanochemistry dates back to 1988 with the first studies on metal alloys. With the progress of time, it has flourished not only in the field of organic chemistry, but also in other scientific fields due to the enormous interest of Italian researchers in the various advantages brought by this technique ...
Francesco Basoccu, Lidia De Luca, Andrea Porcheddu   +2 more
wiley   +1 more source

Molecular Networking‐Guided Discovery of Kyonggic Acids in Massilia spp.

European Journal of Organic Chemistry, Volume 27, Issue 17, May 3, 2024.
The metabolomes of six Massilia strains were analyzed using a molecular‐networking guided approach, revealing interconnections among metabolites. A closer inspection of the most promising strains led to the discovery of novel N‐acylated amino acids, termed kyonggic acids.
Till Steinmetz, Anton Lindig, Stephan Lütz, Markus Nett   +3 more
wiley   +1 more source

The Raputindoles: Novel Cyclopentyl Bisindole Alkaloids from Raputia simulans

Organic Letters, 2010
A novel class of bisindole alkaloids is established by the isolation and structural determination of raputindoles A-D (1-4) from the Amazonian plant Raputia simulans Kallunki (Rutaceae). Complete spectroscopic characterization was accomplished by means of NMR spectroscopy and APCI (+) HRMS.
Vougogiannopoulou, K., Fokialakis, N., Aligiannis, N., Cantrell, C., Skaltsounis, A.-L.   +4 more
openaire   +3 more sources

Genomic‐wide identification and expression analysis of AP2/ERF transcription factors in Zanthoxylum armatum reveals the candidate genes for the biosynthesis of terpenoids

The Plant Genome, Volume 17, Issue 1, March 2024.
Abstract Terpenoids are the main active components in the Zanthoxylum armatum leaves, which have extensive medicinal value. The Z. armatum leaf is the main by‐product in the Z. armatum industry. However, the transcription factors involved in the biosynthesis of terpenoids are rarely reported.
Xiaomeng Liu, Weiwei Zhang, Ning Tang, Zexiong Chen, Shen Rao, Hua Cheng, Chengrong Luo, Jiabao Ye, Shuiyuan Cheng, Feng Xu   +9 more
wiley   +1 more source

The Chemistry of Grandifoline, a Bisindole Alkaloid

, 1979
Department of Pure Chemistry, University College of Science, 92, Acharya P. C.
openaire   +2 more sources

Synthesis of Alkaloids and Compounds Containing the 3,4‐Benzomorphan Scaffold

European Journal of Organic Chemistry, Volume 27, Issue 1, January 2, 2024.
This review summarizes the biosynthesis and the synthesis of several biologically active natural compounds (i. e., alkaloids) and other related compounds containing the hexahydro‐2,6‐methano‐1‐benzazocine structure (i. e., 3,4‐benzomorphan scaffold). Abstract Several natural products, bearing an embedded hexahydro‐2,6‐methano‐1‐benzazocine framework (3,
Laura G. Rodríguez, Josep Bonjoch, Ben Bradshaw   +2 more
wiley   +1 more source

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 1, January 2024.
Abstract Breast cancer is the most prevalent cancer worldwide and its incidence increases with age, posing a significant threat to women's health globally. Due to the clinical heterogeneity of breast cancer, the majority of patients develop drug resistance and metastasis following treatment.
Anqi Ge, Qi He, Da Zhao, Yuwei Li, Junpeng Chen, Ying Deng, Wang Xiang, Hongqiao Fan, Shiting Wu, Yan Li, Lifang Liu, Yue Wang   +11 more
wiley   +1 more source

Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of Cyphostemma adenocaule: A Combined In Vitro and In Silico Study

Journal of Tropical Medicine, Volume 2024, Issue 1, 2024.
Cyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant.
Hadush Gebrehiwot, Yadessa Melaku, Muhdin Aliye, Urgessa Ensermu, Aman Dekebo, Milkyas Endale, Daniel Rentsch, Mo Hunsen, Zhengwei Huang   +8 more
wiley   +1 more source

Circular dichroism studies of bisindole Vinca alkaloids

Tetrahedron, 1998
Abstract The analysis of a series of seventeen vinblastine analogs by circular dichroism is described. Exciton coupling of the indole and indoline chromophores of these compounds provides a general, non-empirical method for the assignment of the C16′ configuration with the bioactive C16′-S and the inactive C16′-R analogs giving rise, respectively, to
Craig A. Parish, Jian-Guo Dong, William G. Bornmann, Joan Chang, Koji Nakanishi, Nina Berova   +5 more
openaire   +1 more source

Macroline–Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana

, 2019
A methanol extract of the stem bark of the Malayan Alstonia penangiana provided seven new bisindole alkaloids, comprising six macroline–sarpagine alkaloids (angustilongines E–K, 1–6) and one macroline–pleiocarpamine bisindole alkaloid (angustilongine L ...
Yun-Yee Low, Toh-Seok Kam, Joanne Soon-Yee Yeap (5205269), Kae-Shin Sim, Chun-Hoe Tan, Siew-Huah Lim (1426534), Hazwani Mat Saad (7533452), Hazwani Mat Saad, Siew-Huah Lim, Joanne Soon-Yee Yeap, Yun-Yee Low (1426531), Chun-Hoe Tan (7533455), Kae-Shin Sim (666138), Toh-Seok Kam (1426537)   +13 more
core   +1 more source