Results 71 to 80 of about 1,599 (196)

Mechanochemistry in Organic Synthesis: An Italian Journey through Innovations

European Journal of Organic Chemistry, Volume 27, Issue 30, August 12, 2024.
The contribution of Italy to the development of mechanochemistry dates back to 1988 with the first studies on metal alloys. With the progress of time, it has flourished not only in the field of organic chemistry, but also in other scientific fields due to the enormous interest of Italian researchers in the various advantages brought by this technique ...
Francesco Basoccu, Lidia De Luca, Andrea Porcheddu   +2 more
wiley   +1 more source

Molecular Networking‐Guided Discovery of Kyonggic Acids in Massilia spp.

European Journal of Organic Chemistry, Volume 27, Issue 17, May 3, 2024.
The metabolomes of six Massilia strains were analyzed using a molecular‐networking guided approach, revealing interconnections among metabolites. A closer inspection of the most promising strains led to the discovery of novel N‐acylated amino acids, termed kyonggic acids.
Till Steinmetz, Anton Lindig, Stephan Lütz, Markus Nett   +3 more
wiley   +1 more source

Indole alkaloids from marine sources as ootential leads againstinfectious diseases [PDF]

, 2014
Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious
Araújo Júnior, João Xavier de, Barbosa Filho, José Maria, Barbosa, Daniel P., Barreto, Rosana de Souza Siqueira, França, Paulo Henrique Barcellos, Quintans Júnior, Lucindo José, Quintans, Jullyana de Souza Siqueira, Ribeiro, Êurica Adélia Nogueira, Santana, Antônio Euzébio Goulart, Santos, Bárbara Viviana de Oliveira, Silva, Daniel Lira da   +10 more
core   +1 more source

Genomic‐wide identification and expression analysis of AP2/ERF transcription factors in Zanthoxylum armatum reveals the candidate genes for the biosynthesis of terpenoids

The Plant Genome, Volume 17, Issue 1, March 2024.
Abstract Terpenoids are the main active components in the Zanthoxylum armatum leaves, which have extensive medicinal value. The Z. armatum leaf is the main by‐product in the Z. armatum industry. However, the transcription factors involved in the biosynthesis of terpenoids are rarely reported.
Xiaomeng Liu, Weiwei Zhang, Ning Tang, Zexiong Chen, Shen Rao, Hua Cheng, Chengrong Luo, Jiabao Ye, Shuiyuan Cheng, Feng Xu   +9 more
wiley   +1 more source

Synthesis of Alkaloids and Compounds Containing the 3,4‐Benzomorphan Scaffold

European Journal of Organic Chemistry, Volume 27, Issue 1, January 2, 2024.
This review summarizes the biosynthesis and the synthesis of several biologically active natural compounds (i. e., alkaloids) and other related compounds containing the hexahydro‐2,6‐methano‐1‐benzazocine structure (i. e., 3,4‐benzomorphan scaffold). Abstract Several natural products, bearing an embedded hexahydro‐2,6‐methano‐1‐benzazocine framework (3,
Laura G. Rodríguez, Josep Bonjoch, Ben Bradshaw   +2 more
wiley   +1 more source

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest [PDF]

, 2018
Although the chemical warfare between invasive and native species has become a central problem in invasion biology, the molecular mechanisms by which bioactive metabolites from invasive pests influence local communities remain poorly characterized.
Amodeo, Pietro, Calignano, Antonio, Carbone, Marianna, Cutignano, Adele, D'Aniello, Biagio, D'Aniello, Enrico, Defranoux, Fanny, Di Marzo, Vincenzo, Felline, Serena, Fellous, Tariq, Gentile, Alessandra, Giuliani, Maria Elisa, Gorbi, Stefania, Grauso, Laura, Magliozzi, Laura, Martella, Andrea, Mollo, Ernesto, Polese, Gianluca, Regoli, Francesco, Silvestri, Cristoforo, Terlizzi, Antonio, Vitale, Rosa Maria   +21 more
core   +1 more source

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 1, January 2024.
Abstract Breast cancer is the most prevalent cancer worldwide and its incidence increases with age, posing a significant threat to women's health globally. Due to the clinical heterogeneity of breast cancer, the majority of patients develop drug resistance and metastasis following treatment.
Anqi Ge, Qi He, Da Zhao, Yuwei Li, Junpeng Chen, Ying Deng, Wang Xiang, Hongqiao Fan, Shiting Wu, Yan Li, Lifang Liu, Yue Wang   +11 more
wiley   +1 more source

Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities. [PDF]

, 2014
With reports of pandrug-resistant bacteria causing untreatable infections, the need for new antibacterial therapies is more pressing than ever. Alkaloids are a large and structurally diverse group of compounds that have served as scaffolds for important ...
Cushnie, Benjamart, Cushnie, T.P. Tim, Lamb, Andrew J.   +2 more
core   +1 more source

First De Novo Synthesis of the Bisindole Alkaloid Vinblastine.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +4 more sources

Circular dichroism studies of bisindole Vinca alkaloids

Tetrahedron, 1998
Abstract The analysis of a series of seventeen vinblastine analogs by circular dichroism is described. Exciton coupling of the indole and indoline chromophores of these compounds provides a general, non-empirical method for the assignment of the C16′ configuration with the bioactive C16′-S and the inactive C16′-R analogs giving rise, respectively, to
Craig A. Parish, Jian-Guo Dong, William G. Bornmann, Joan Chang, Koji Nakanishi, Nina Berova   +5 more
openaire   +1 more source