Cyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant.
Hadush Gebrehiwot +8 more
wiley +1 more source
Iridium-catalyzed aza-spirocyclization of indole-tethered amides: an interrupted Pictet–Spengler reaction [PDF]
A mild, reductive spirocyclization of indole-linked amides and lactams for the efficient and selective synthesis of aza-spirocyclic indoline products is described.
Dixon, Darren, Gabriel, P, Gregory, AW
core +2 more sources
Asymmetric organocatalytic synthesis of 4,6-bis-(1H-indole-3-yl)-piperidine-2 carboxylates [PDF]
Peer ...
Bihlmeier, Angela +4 more
core +2 more sources
A Review on Tabernaemontana spp.: Multipotential Medicinal Plant [PDF]
Tabernaemontana is one of the genera that is used in Chinese, Ayurvedic and Thai traditional medicine for the treatment several diseases. From a chemical point of view, the great majority of Tabernaemontana species have already been subjected to ...
Athipornchai, Anan
core +1 more source
Immunological exploration based studies on Strychnos nux-vomica regarding antigen specific immune response [PDF]
In an effort to determine its cytotoxicity as well as antigen specific immune activity of aqueous leaves extract of Strychnos nux-vomica using hepatitis B vaccine containing surface antigen (HBsAg; 20 µg/ml) pertaining to antibody production and ...
Gupta, Amit Joginder
core +2 more sources
Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Indole Alkaloids Isolated from Catharanthus roseus (L.) G. Don Cultivated Conventionally and Derived from In vitro Cultures [PDF]
Catharanthus roseus (periwinkle) is a medicinal plant commonly known for its wide biological activity. In many countries different parts of this plant are used for the treatment of diabetes, hypertension and for menstrual regulation.
GRZESZCZUK, Monika +3 more
core +2 more sources
Rare Bisindole Alkaloids from the Amazonian Tree Raputia simulans
AbstractThe stem bark of Raputia simulans (Rutaceae) has been reported to contain simple and dimeric indole alkaloids. Further phytochemical investigation of R. simulans stem bark resulted in the isolation of three new alkaloids. These compounds represent a relatively new category of dimeric indole alkaloids with a cyclohexene moiety in their core ...
Vougogiannopoulou, K. +3 more
openaire +3 more sources
Radical mediated heterocycle functionalization: methodology development and natural product synthesis [PDF]
Substituted heterocycles are common building-blocks for biologically relevant molecules and represent challenging synthetic targets. Due to limited methods available for their preparation and derivatization, direct C-H functionalization protocols offer ...
Furst, Laura
core +1 more source
Exploring the production of high-value compounds in plant Catharanthus roseus hairy roots and yeast Yarrowia lipolytica [PDF]
This dissertation focuses on studying the production of two categories of high-value compounds in bio organisms. The first group is terpenoid indole alkaloids (TIAs) in plant Catharanthus roseus, and the second group is wax esters, one of fatty acid ...
Zhao, Le
core +3 more sources
Synthesis of 3,6-Bis(5’-bromo-3’-indolyl)-1,4-dimethypiperazine-2,5-dione [PDF]
The one-pot synthesis of 3,6-bis(5’-bromo-3’-indolyl)-1,4-dimethylpiperazine- 2,5-dione is reported. Sarcosine anhydride is brominated and immediately reacted with 5-bromoindole to produce the product, which is characterized by 1H NMR, MS and ...
Crooke, Stephen N. +2 more
core +1 more source

