Results 71 to 80 of about 1,584 (196)

Molecular Networking‐Guided Discovery of Kyonggic Acids in Massilia spp.

open access: yesEuropean Journal of Organic Chemistry, Volume 27, Issue 17, May 3, 2024.
The metabolomes of six Massilia strains were analyzed using a molecular‐networking guided approach, revealing interconnections among metabolites. A closer inspection of the most promising strains led to the discovery of novel N‐acylated amino acids, termed kyonggic acids.
Till Steinmetz   +3 more
wiley   +1 more source

Genomic‐wide identification and expression analysis of AP2/ERF transcription factors in Zanthoxylum armatum reveals the candidate genes for the biosynthesis of terpenoids

open access: yesThe Plant Genome, Volume 17, Issue 1, March 2024.
Abstract Terpenoids are the main active components in the Zanthoxylum armatum leaves, which have extensive medicinal value. The Z. armatum leaf is the main by‐product in the Z. armatum industry. However, the transcription factors involved in the biosynthesis of terpenoids are rarely reported.
Xiaomeng Liu   +9 more
wiley   +1 more source

Stereoselective Synthesis of 2-(2-Aminoalkyl)- and 1,3-Disubstituted Tetrahydro-1H-pyrido[4,3-b]- Benzofuran and Indole Derivatives [PDF]

open access: yes, 2016
The addition of an allenyl indium intermediate to chiral N-tert-butanesulfinyl imines 7 proceeds with high levels of diastereocontrol. The resulting homopropargylic amine derivatives 10 were transformed into 2-(2-aminoalkyl)benzofuran and indole ...
Foubelo, Francisco   +2 more
core   +3 more sources

Synthesis of Alkaloids and Compounds Containing the 3,4‐Benzomorphan Scaffold

open access: yesEuropean Journal of Organic Chemistry, Volume 27, Issue 1, January 2, 2024.
This review summarizes the biosynthesis and the synthesis of several biologically active natural compounds (i. e., alkaloids) and other related compounds containing the hexahydro‐2,6‐methano‐1‐benzazocine structure (i. e., 3,4‐benzomorphan scaffold). Abstract Several natural products, bearing an embedded hexahydro‐2,6‐methano‐1‐benzazocine framework (3,
Laura G. Rodríguez   +2 more
wiley   +1 more source

Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities. [PDF]

open access: yes, 2014
With reports of pandrug-resistant bacteria causing untreatable infections, the need for new antibacterial therapies is more pressing than ever. Alkaloids are a large and structurally diverse group of compounds that have served as scaffolds for important ...
Cushnie, Benjamart   +2 more
core   +1 more source

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 1, January 2024.
Abstract Breast cancer is the most prevalent cancer worldwide and its incidence increases with age, posing a significant threat to women's health globally. Due to the clinical heterogeneity of breast cancer, the majority of patients develop drug resistance and metastasis following treatment.
Anqi Ge   +11 more
wiley   +1 more source

Iridium-catalyzed aza-spirocyclization of indole-tethered amides: an interrupted Pictet–Spengler reaction [PDF]

open access: yes, 2019
A mild, reductive spirocyclization of indole-linked amides and lactams for the efficient and selective synthesis of aza-spirocyclic indoline products is described.
Dixon, Darren, Gabriel, P, Gregory, AW
core   +2 more sources

Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of Cyphostemma adenocaule: A Combined In Vitro and In Silico Study

open access: yesJournal of Tropical Medicine, Volume 2024, Issue 1, 2024.
Cyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant.
Hadush Gebrehiwot   +8 more
wiley   +1 more source

A Review on Tabernaemontana spp.: Multipotential Medicinal Plant [PDF]

open access: yes, 2018
Tabernaemontana is one of the genera that is used in Chinese, Ayurvedic and Thai traditional medicine for the treatment several diseases. From a chemical point of view, the great majority of Tabernaemontana species have already been subjected to ...
Athipornchai, Anan
core   +1 more source

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