Results 191 to 200 of about 61,821 (357)

Twelve‐Month Real‐World Outcomes of Faricimab for Treatment‐Naive Neovascular AMD in Australia

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To provide insights into the effectiveness and safety of faricimab for treatment‐naïve eyes with neovascular age‐related macular degeneration (nAMD). Methods A retrospective cohort study using a prospectively‐designed registry. Treatment‐naïve eyes with nAMD in Australia starting treatment with faricimab between Jan 2023–Sep 2024 ...
Mark Gillies   +8 more
wiley   +1 more source

Missense variants in human forkhead transcription factors reveal determinants of forkhead DNA bispecificity [PDF]

open access: green
Jessica King   +5 more
openalex   +1 more source

Lactate‐Induced Liquid–Liquid Phase Separation of HIF‐1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer

open access: yesCell Proliferation, EarlyView.
Lactate‐Induced Liquid‐Liquid Phase Separation of HIF‐1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer.
Chenhao Fu   +14 more
wiley   +1 more source

Bispecific and multispecific immune engagers for redirecting innate and adaptive immunity against hematologic cancers. [PDF]

open access: yesDiscov Oncol
Ardah MT   +8 more
europepmc   +1 more source

T cells expressing CD19-specific Engager Molecules for the Immunotherapy of CD19-positive Malignancies [PDF]

open access: yes, 2017
Arber, Caroline   +11 more
core   +1 more source

Bispecific antibody toxicities

open access: yesCanadian Medical Association Journal
Britto, Joanne   +3 more
openaire   +2 more sources

Elranatamab in Relapsed/Refractory Multiple Myeloma: Mechanisms, Clinical Evidence, and Emerging Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Relapsed and refractory multiple myeloma (RRMM) remains associated with poor outcomes, particularly in patients exposed or refractory to proteasome inhibitors, immunomodulatory agents, and anti‐CD38 monoclonal antibodies. Targeting B‐cell maturation antigen (BCMA) has emerged as an effective therapeutic strategy, prompting the development of ...
Maria Eugenia Alvaro   +12 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese   +12 more
wiley   +1 more source

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