Results 251 to 260 of about 1,442,988 (353)

Anti‐CD3 × anti‐GD2 bispecific antibody redirects T‐cell cytolytic activity to neuroblastoma targets [PDF]

, 2012
Maxim Yankelevich, Sri Vidya Kondadasula, Archana Thakur, Steven Buck, Nai‐Kong V. Cheung, Lawrence G. Lum   +5 more
openalex   +1 more source

Targeting capacity, safety and efficacy of engineered extracellular vesicles delivered by transdermal microneedles to treat plasmacytoma in mice

Clinical and Translational Medicine, Volume 15, Issue 5, May 2025.
A schematic illustration of engineered EVs (CD38‐EVs‐Dox) delivered via MNs or intravenous administration for plasmacytoma treatment. CD38‐EVs encapsulated within MNs effectively enhanced tumour cell targeting compared to standard EVs in MNs and intravenously administered CD38‐EVs, with reduced lung and spleen distribution.
Yulin Cao, Xuan Hu, Di Wu, Yuxuan Jiang, Yali Yu, Shan Wang, Wenlan Chen, Yaoying Long, Liuyue Xu, Jiao Qu, Bianlei Yang, Blal Chakhabi, Hongxiang Wang, Yong Deng, Lei Chen, Zhichao Chen, Qiubai Li   +16 more
wiley   +1 more source

Defining infection risk of bispecific antibodies for myeloma. [PDF]

Blood Adv
Hammond SP.
europepmc   +1 more source

Dual-targeting immunotherapy of lymphoma: potent cytotoxicity of anti-CD20/CD74 bispecific antibodies in mantle cell and other lymphomas [PDF]

, 2012
Pankaj Gupta, David M. Goldenberg, Edmund A. Rossi, Thomas M. Cardillo, John C. Byrd, Natarajan Muthusamy, Richard R. Furman, Chien‐Hsing Chang   +7 more
openalex   +1 more source

Novel Trispecific Neutralizing Antibodies With Enhanced Potency and Breadth Against Pan‐Sarbecoviruses

MedComm, Volume 6, Issue 5, May 2025.
Multispecific antibodies harness the advantages of two or more mAbs. In this study, we designed novel trispecific antibodies, Tri‐1 and Tri‐2, derived from our previously identified mAbs, PW5‐5, PW5‐535, and PW5‐570. These trispecific antibodies exhibited enhanced binding affinity and broad neutralization capacity against SARS‐CoV, SARS‐CoV‐2 variants,
Rui Qiao, Yuanchen Liu, Qiyu Mao, Jiayan Li, Yinying Lu, Jialu Shi, Chen Li, Jizhen Yu, Jiami Gong, Xun Wang, Yuchen Shao, Lei Sun, Wenhong Zhang, Hongjie Yu, Hin Chu, Pengfei Wang, Xiaoyu Zhao   +16 more
wiley   +1 more source

Bispecific antibodies in the treatment of multiple myeloma. [PDF]

Blood Cancer J
Devasia AJ, Chari A, Lancman G.
europepmc   +1 more source

Ethnic Sensitivity Assessment of Mosunetuzumab Pharmacokinetics and Pharmacodynamics in Chinese Patients With Relapsed or Refractory Follicular Lymphoma

Clinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Mosunetuzumab, a CD20 × CD3 T‐cell‐engaging bispecific antibody, redirects T cells to eliminate malignant B cells. The purpose of YO43555 was to assess the pharmacokinetics (PK), safety, tolerability, and efficacy of mosunetuzumab as a single agent in Chinese patients with relapsed/refractory follicular lymphoma (R/R FL).
Junyi Li, Michael Z. Liao, Justin Wilkins, Elicia Penuel, Bei Wang, Shweta Vadhavkar, Kun Peng, Junning Cao, Zhiming Li, Ye Zhang, Wenjin Li, Donghang Li, Mingzhu Zhou, Michael C. Wei, Antonia Kwan, Rong Zhao, Chunze Li, Chi‐Chung Li, David C. Turner   +18 more
wiley   +1 more source

Correction for Ramos et al., "Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase". [PDF]

mBio
Ramos KE, Okba NMA, Tan J, Bandawane P, Meade P, Loganathan M, Francis B, Shulenin S, Holtsberg FW, Aman MJ, McMahon M, Krammer F, Lai JR.   +12 more
europepmc   +1 more source

Relapsed/Refractory Follicular Lymphoma: Current Advances and Emerging Perspectives

European Journal of Haematology, Volume 114, Issue 5, Page 775-784, May 2025.
ABSTRACT Follicular lymphoma (FL) is a prevalent indolent non‐Hodgkin lymphoma (NHL) characterized by a relapsing course and eventual refractoriness to therapy. Despite advancements in treatment, FL remains incurable, necessitating ongoing research into novel therapeutic strategies.
Giulio Caridà, Enrica Antonia Martino, Antonella Bruzzese, Daniele Caracciolo, Caterina Labanca, Francesco Mendicino, Eugenio Lucia, Virginia Olivito, Teresa Rossi, Antonino Neri, Ernesto Vigna, Pierfrancesco Tassone, Pierosandro Tagliaferri, Fortunato Morabito, Massimo Gentile   +14 more
wiley   +1 more source

Reversal of Endothelial Cell Anergy by T Cell-Engaging Bispecific Antibodies. [PDF]

Cancers (Basel)
Gonçalves M, Warwas KM, Meyer M, Schwartz-Albiez R, Bulbuc N, Zörnig I, Jäger D, Momburg F.   +7 more
europepmc   +1 more source