Results 201 to 210 of about 1,443,667 (357)

130. Targeting of Adenovirus Vectors to Mesothelin Via a Bispecific Antibody Reveals Enhanced Gene Transfer to Human Pancreatic Cancer Cells [PDF]

open access: hybrid, 2004
MA van Geer   +6 more
openalex   +1 more source

Atezolizumab, obinutuzumab and venetoclax for the treatment of patients with relapsed/refractory B non‐Hodgkin lymphoma: Final analysis of a phase II trial from the LYSA group

open access: yesBritish Journal of Haematology, EarlyView.
Summary Developing new therapeutic regimens for relapsed/refractory (R/R) B non‐Hodgkin lymphoma (NHL) patients remains a significant unmet clinical need. Our objective was to evaluate atezolizumab (ATE), obinutuzumab (OBI) and venetoclax (VEN) combination in patients with R/R NHL who had received at least one prior anti‐CD20‐containing ...
Charles Herbaux   +21 more
wiley   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf   +10 more
wiley   +1 more source

Composite Lymphoma: A Rare Case of Vomiting

open access: yes
United European Gastroenterology Journal, EarlyView.
Changqin Liu, Dongyan Han, Xiaomin Sun
wiley   +1 more source

Opportunities to Modulate Tumor Ecosystem Toward Successful Glioblastoma Immunotherapy

open access: yesCancer Science, EarlyView.
There remain outstanding gaps between the negative results from clinical trials and the actual potential of the immune system for glioblastoma. To bridge this crucial gap, we collaborated with Dr. Mariko Takahashi, an expert in immunobiology and drug development, and Dr. James J.
Mariko Takahashi   +5 more
wiley   +1 more source

Recombinant approaches to IgG-like bispecific antibodies [PDF]

open access: bronze, 2005
Jonathan S. Marvin, Zhenping Zhu
openalex   +1 more source

Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity

open access: yesCancer Immunology and Immunotherapy, 2020
Yan Wang   +17 more
semanticscholar   +1 more source

Bispecific Antibodies and Gene Therapy

open access: yes, 2011
Gene therapy is the transfer of therapeutic genes, via gene transfer vectors, into patients for therapeutic purposes. Different gene therapy strategies are being pursued, including long-term gene correction of monogenetic diseases, eradication of tumor cells in cancer patients, or genetic vaccination for infectious diseases.
openaire   +2 more sources

Home - About - Disclaimer - Privacy