Bisphosphonate Related Osteonecrosis of the Jaw: A Study of 18 Cases Associated with Fungal Infection [PDF]
International Journal of Dentistry, 2014 Osteonecrosis of the jaw (ONJ) is a serious complication associated with oral and intravenous bisphosphonate therapy. Its pathogenesis is not well understood and its management is difficult.
V. Aftimos +3 more
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Bisphosphonate-associated jaw osteonecrosis in the treatment of rheumatoid arthritis [PDF]
RGO: Revista Gaúcha de OdontologiaThis literature review aimed to raise the relationship between rheumatoid arthritis and mandibular osteonecrosis associated with bisphosphonates. The articles were collected in Pubmed, Bireme, Cochrane and Scielo between the years 2000 and 2023, the ...
Gabriela Dias Rosso dos Santos +2 more
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CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma [PDF]
Haematologica, 2011 Osteonecrosis of the jaw is an uncommon but potentially serious complication of bisphosphonate therapy in multiple myeloma. Previous studies showed that the presence of one or two minor alleles of the cytochrome P450, subfamily 2C polypeptide 8 gene ...
Esperanza Such +13 more
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Quality of Life Implications of Bisphosphonate-Associated Osteonecrosis of the Jaw [PDF]
The Oncologist, 2011 AbstractPurpose.Potentially debilitating, osteonecrosis of the jaw (ONJ) is an emerging complication of bisphosphonates. However, its effect on quality of life (QoL) is unknown. We determined the ONJ-related QoL decline in a cancer patient cohort.Patients and Methods.Thirty-four cancer patients with bisphosphonate-associated ONJ completed a telephone ...
Rebecca Anne, Miksad +10 more
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Guidelines for bisphosphonate-associated osteonecrosis of the jaw [PDF]
Evidence-Based Dentistry, 2008 This guideline aimed to provide recommendations for the diagnosis of bisphosphonate-associated osteonecrosis of the jaw in both the oncology and osteoporosis patient populations, for dental and medical practitioners including dentists, oral surgeons, oral pathologists, general practitioners and internal medicine specialists.
Derek Richards
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Pharmacogenetics of Bisphosphonate-associated Osteonecrosis of the Jaw [PDF]
Oral and Maxillofacial Surgery Clinics of North America, 2015 Osteonecrosis of the jaws (ONJ) is a potentially severe disorder that develops in a subgroup of individuals who have used bisphosphonate (BP) medications. Several clinical risk factors have been associated with the risk of ONJ development, but evidence is limited and in most instances ONJ remains an unpredictable adverse drug reaction.
Fung, PL +4 more
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Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFβ1-signaling and increased Galectin-3 expression: A histological study on biopsies [PDF]
Journal of Translational Medicine, 2011 BackgroundBisphosphonate associated osteonecrosis of the jaw (BRONJ) implies an impairment in oral hard- and soft tissue repair. An understanding of the signal transduction alterations involved can inform therapeutic strategies.
Falk Wehrhan +7 more
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Endodontic therapy and Medication-related osteonecrosis of the jaw onset: a scoping review and expert opinion-based qualitative meta-synthesis [PDF]
BMC Oral HealthIntroduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious side effect of bone-modifying agents (BMAs), including bisphosphonates, denosumab, and antiangiogenic drugs.
R. Mauceri +5 more
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Bisphosphonate‐Associated Osteonecrosis of the Jaw [PDF]
Definitions, 2020 Sundeep Khosla +23 more
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Impact of dental care in the prevention of bisphosphonate-associated osteonecrosis of the jaw: a single-center clinical experience [PDF]
Annals of Oncology, 2011 Anna Maria Vandone +7 more
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