Results 71 to 80 of about 4,610 (193)

Quantitative ultrasound at the hand phalanges in patients with bisphosphonate-related osteonecrosis of the jaws

Brazilian Oral Research, 2015
Patients with bisphosphonate-related osteonecrosis of the jaws (BRONJ) who received intravenous or oral bisphosphonates (BP) were selected for determination of their bone microarchitecture as a risk predictor of BRONJ development.
Ana Carolina Fragoso MOTTA, Leandro Dorigan de MACEDO, Gisele Guimarães SANTOS, Carlos Tostes GUERREIRO, Tatiane FERRARI, Thais Feitosa Leitão de OLIVEIRA, Paulo Sérgio da Silva SANTOS, Christiano de OLIVEIRA-SANTOS, Hilton Marcos Alves RICZ, Samuel Porfírio XAVIER, Odilon IANNETTA   +10 more
doaj   +1 more source

Comparing the effects of low-level laser therapy and gaseous ozone as a preventive measure on medication-related osteonecrosis of the jaws following tooth extraction: a rat model

European Journal of Medical Research
Objectives Use of numerous medications such as tyrosine kinase inhibitors (sunitinib), monoclonal antibodies (bevacizumab), fusion proteins (aflibercept), mTOR inhibitors (everolimus), radiopharmaceuticals (radium 223), selective estrogen receptor ...
Öznur Özalp, Oğuzcan Göksu, Havva Serap Toru, Mehmet Ali Altay, Alper Sindel   +4 more
doaj   +1 more source

Re-appraisal of dental clearance protocol before anti-resorptive agents for osteoporosis using the modified Delphi technique

BMC Oral Health
Background Patients undergoing anti-resorptive agent (ARA) therapy are at risk of medication-related osteonecrosis of the jaw (MRONJ). Although existing guidelines encourage dental clearance prior to the initiation of ARA therapy, details on risk ...
Sarah Kho Xian Chua, Ruth Wei Choe, Catherine Hsu Ling Hong, Chee Weng Yong, Chien Joo Sim, Chong Meng Tay, Gabriel Keng Yan Lee, Jacinta Xiaotong Lu, Jing Li Lum, Joanne Ngo Uy, Mei Na Tan, Ren Jie Jacob Chew, Wataru Ode, Wendy Chia-Wei Wang   +13 more
doaj   +1 more source

Author response to OSIN-D-23–00510, “Comment on: A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral bisphosphonate therapy: can primary wound closure and a drug holiday really prevent MRONJ?” [PDF]

, 2023
Takumi Hasegawa
openalex   +1 more source

Osteonecrose da mandíbula em paciente portador de mieloma múltiplo: patologia secundária ao uso do pamidronato Jaw osteonecrosis in a patient suffering from multiple myeloma: pathology secondary to pamidronate therapy

Revista Brasileira de Hematologia e Hemoterapia, 2005
Descreveremos a ocorrência de osteonecrose da mandíbula associada ao uso de pamidronato (Aredia ) em uma paciente portadora de mieloma múltiplo. Apesar de não ser possível provar definitivamente a associação entre a terapia com bisfosfonatos e a ...
Andréia C. Melo, Marcos Bastos, Maria R. Bastos, Adrieli S. Loureiro, Sérgio S. Araújo   +4 more
doaj   +1 more source

Systemic Ozone Therapy Improves Oral Hard and Soft Tissue Healing in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Study in Senescent Female Rats

Biomedicines
Background/Objectives: Medication-related osteonecrosis of the jaw (MRONJ) is a challenging condition often associated with bisphosphonate use, leading to impaired bone healing and difficult clinical management.
Leonardo Alan Delanora, Tiburtino José de Lima Neto, Tiago Esgalha da Rocha, Glauco Rodrigues Carmo Silveira, Liran Levin, Jamil Awad Shibli, Edilson Ervolino, Carlos Fernando Mourão, Leonardo P. Faverani   +8 more
doaj   +1 more source

The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification [PDF]

Journal of Applied Oral Science
Objective For treatment of medication-related osteonecrosis of the jaw, one proposed approach is the use of a topical agent to block entry of these medications in oral soft tissues.
Jacob KIRBY, Makayla STANDFEST, Jessica BINKLEY, Charles BARNES, Evan BROWN, Tyler CAIRNCROSS, Alex CARTWRIGHT, Danielle DADISMAN, Colten MOWAT, Daniel WILMOT, Theodore HOUSEMAN, Conner MURPHY, Caleb ENGELSMAN, Josh HALLER, Daniel JONES   +14 more
doaj   +1 more source

Bisphosphonate-associated osteonecrosis of the jaw: A key role of inflammation?

Bone, 2009
Osteonecrosis of the jaw (ONJ) can be associated with nitrogen-containing bisphosphonates (NBPs) therapy. Various mechanisms of NBP-associated ONJ have been proposed and there is currently no consensus of the underlying pathogenesis. The detailed medical and dental histories of 30 ONJ patients treated with NBPs for malignant diseases (24) or ...
Lesclous, Philippe, Abi Najm, Semaan, Carrel, Jean-Pierre, Baroukh, B, Lombardi, Tommaso, Willy, JP, Rizzoli, René, Saffar, JL, Samson, Jacky   +8 more
openaire   +3 more sources

Nonexposed Variant of Bisphosphonate-associated Osteonecrosis of the Jaw: A Case Series [PDF]

, 2010
Stefano Fedele, Stephen Porter, Francesco D’Aiuto, Suad Aljohani, Paolo Vescovi, Maddalena Manfredi, Paolo G. Arduino, Roberto Broccoletti, Anna Musciotto, Olga Di Fede, Tony S. Lazarovici, Giuseppina Campisi, Naom Yarom   +12 more
openalex   +1 more source

Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate

Autopsy and Case Reports, 2021
Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease ...
Marília A. Figueiredo, Frederico Buhatem Medeiros, Karem López Ortega   +2 more
doaj