Results 81 to 90 of about 9,802 (262)

Effect of metformin on inflammation and bone damage in a rat model of medication‐related osteonecrosis of the jaw

European Journal of Oral Sciences, EarlyView.
Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Liviane Maria Alves Rabelo, Mariana Vasconcelos Guimarães, Aurilene Gomes Cajado, José Vitor Mota Lemos, Felipe Domingos de Sousa, Nylane Maria Nunes Alencar, Vilma de Lima, Paulo Goberlânio de Barros Silva, Ana Paula Negreiros Nunes Alves, Deysi Viviana Tenazoa Wong, Roberto César Pereira Lima‐Júnior   +10 more
wiley   +1 more source

Recommendations for bone‐directed therapy in patients with neuroendocrine tumour skeletal metastases at the New Zealand National Neuroendocrine Tumour Multidisciplinary Meeting

Internal Medicine Journal, EarlyView.
Abstract The role of anti‐resorptive agents in patients with bone metastases from neuroendocrine neoplasms is unclear. Our aim was to review bone‐specific treatment recommendations by the New Zealand National Neuroendocrine Tumour Multidisciplinary Meeting (MDM).
Gayle Radley, Marianne S Elston, Ben Lawrence, Veronica Boyle   +3 more
wiley   +1 more source

DENOSUMAB-RELATED OSTEONECROSIS OF THE JAWS: A CASE REPORT [PDF]

Journal of IMAB, 2017
Bisphosphonates are potent and effective drugs frequently used to prevent the skeletal complications associated with postmenopausal osteoporosis in women, to manage patients with multiple myeloma, hypercalcemia, and metastasis of cancer to the bone. The
Milena Petkova, Pavel Stanimirov
doaj   +1 more source

Patients' Awareness of the Complications of Bisphosphonate Therapy

Dentistry 3000, 2022
INTRODUCTION: Bisphosphonate-associated osteonecrosis of the jaws (BAONJ) is a serious complication that has been reported predominantly in cancer patients treated with Bisphosphonate (BP).
Meri Hristamyan, Ralista Raycheva, Veselka Hristamyan   +2 more
doaj   +1 more source

Current Controversies in Classification, Management, and Prevention of Bisphosphonate-Related Osteonecrosis of the Jaw [PDF]

, 2014
EDITORIA
Ascani, G., Campisi, G., Luis Manuel Junquera Gutierrez, A.   +2 more
core  

Bisphosphonate-related osteonecrosis of the jaw (BRONJ): run dental management designs and issues in diagnosis. [PDF]

, 2007
Recently, jawbone osteonecrosis has been largely reported as a potential adverse effect of bisphosphonate (BP) administration. Because of the peculiar pharmacokinetic and pharmacodynamic features of the BF (mainly for i.v. administration), their efficacy
BADALAMENTI, Giuseppe, CAMPISI, Giuseppina, DI FEDE, Olga, FULFARO, Fabio, GEBBIA, Nicolo', LO CASTO, Antonio, LO MUZIO L, MUSCIOTTO, Anna, RUSSO, Antonio   +8 more
core   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Comments on "diagnosis and management of osteonecrosis of the jaw: A systematic review and international consensus" [PDF]

, 2015
Letter to ...
Assaf, Bedogni, Bedogni, Carlson, Colella, Fedele, Fedele, Fliefel, Graziani, Hoff, Holmdahl, Humphrey, Hutchinson, Jacobsen, Junquera, Khan, Kyrgidis, Liberati, Mawardi, Mucke, Nicolatou-Galitis, Noordzij, Otto, Patel, Pautke, Peters, Ruggiero, Ruggiero, Rupel, Schiodt, Schubert, Scully, Sharif, Sonnier, Stockmann, Then, Vescovi, Walter, Yarom, Yuan   +39 more
core   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Comparison of the Effectiveness of Conservative and Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: a Systematic Review

eJournal of Oral Maxillofacial Research, 2023
Objectives: The objective of this systematic review is to evaluate the current knowledge on the effectiveness of conservative and surgical treatment of medication-related osteonecrosis of the jaw.
Rial Seluki, Moshe Seluki, Inga Vaitkeviciene, Egle Jagelaviciene   +3 more
doaj   +1 more source